Alkylation

Known as: Alkylation Process, Alkylations, alkyl transfer 
Alkylating Activity in biological systems is typically a process of covalent bonding in which a chemical substance replaces hydrogen atom(s) in… (More)
National Institutes of Health

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Review
2012
Review
2012
Alkylating agents constitute a major class of frontline chemotherapeutic drugs that inflict cytotoxic DNA damage as their main… (More)
  • figure 1
  • figure 2
  • figure 3
  • figure 4
  • figure 5
Is this relevant?
Highly Cited
2008
Highly Cited
2008
Electrophilic compounds are a newly recognized class of redox-active neuroprotective compounds with electron deficient… (More)
Is this relevant?
Review
2006
Review
2006
Following the induction of DNA damage, a prominent route of cell inactivation is apoptosis. During the last ten years, specific… (More)
Is this relevant?
Highly Cited
2003
Highly Cited
2003
Repair of DNA damage is essential for maintaining genome integrity, and repair deficiencies in mammals are associated with cancer… (More)
  • figure 1
  • figure 2
  • figure 3
  • figure 4
Is this relevant?
Highly Cited
2003
Highly Cited
2003
Chemical mutagenesis has been the workhorse of traditional genetics, but it has not been possible to determine underlying rates… (More)
  • figure 2
  • table 1
  • table 2
  • table 3
  • table 4
Is this relevant?
Review
1999
Review
1999
In vitro selection allows rare functional RNA or DNA molecules to be isolated from pools of over 10(15) different sequences. This… (More)
  • figure 1
  • table 1
  • table 1
  • figure 3
  • figure 4
Is this relevant?
Highly Cited
1998
Highly Cited
1998
Although mass spectrometric peptide mapping has become an established technique for the rapid identification of proteins isolated… (More)
  • figure 1
  • figure 2
  • figure 3
  • figure 4
  • table 1
Is this relevant?
Highly Cited
1996
Highly Cited
1996
The possible relationship of selenium to immunological function which has been suggested for decades was investigated in studies… (More)
  • figure 1
  • figure 2
  • table 1
  • table 2
Is this relevant?
Highly Cited
1990
Highly Cited
1990
Many plants, as well as other organisms, accumulate betaine (N,N,N-trimethylglycine) as a nontoxic or protective osmolyte under… (More)
  • figure 1
  • figure 3
  • figure 2
  • figure 4
Is this relevant?
Highly Cited
1969
Highly Cited
1969
BIOLOGICAL alkylating agents—“mustards”, ethylenimines, epoxides and alkyl alkanesulphonates—have been believed to induce… (More)
Is this relevant?