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Dealkylation

Known as: Dealkylations 
The removing of alkyl groups from a compound. (From McGraw-Hill Dictionary of Scientific and Technical Terms, 5th ed)
National Institutes of Health

Papers overview

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Highly Cited
2010
Highly Cited
2010
Tabun is a warfare agent that inhibits human acetylcholinesterase (hAChE) by rapid phosphylation of the catalytic serine. A time… Expand
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Highly Cited
2000
Highly Cited
2000
The present study investigates the degradation of atrazine (2-chloro-4-(ethylamino)-6-isopropylamino-s-triazine) by ozone and OH… Expand
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Highly Cited
1996
Highly Cited
1996
Alfentanil, sufentanil, and fentanyl are synthetic opioids that are metabolized by oxidative N-dealkylation in the liver. We have… Expand
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Highly Cited
1994
Highly Cited
1994
The O-dealkylations of ethoxyresorufin and pentoxyresorufin are widely used activity probes for measuring the cytochrome P450… Expand
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Highly Cited
1985
Highly Cited
1985
The O-dealkylation of pentoxyresorufin (7-pentoxyphenoxazone) by rat liver microsomes was examined. The reaction appeared highly… Expand
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Highly Cited
1985
Highly Cited
1985
The individual members of a homologous series of phenoxazone ethers related to ethoxyresorufin were O-dealkylated, and the parent… Expand
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Highly Cited
1974
Highly Cited
1974
Ethoxyresorufin (7-ethoxyphenoxazone) has been synthesized to serve as a model substrate for the simple, direct, fluorimetric… Expand
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Highly Cited
1972
Highly Cited
1972
  • V. Ullrich, P. Weber
  • Hoppe-Seyler's Zeitschrift fur physiologische…
  • 1972
  • Corpus ID: 32183828
 
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Highly Cited
1965
Highly Cited
1965
Abstract The decrease in the mole fraction of 32 P-pinacolyl methylphosphonic acid ( 32 P-PMPA) derived from acetylcholinesterase… Expand
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Highly Cited
1955
Highly Cited
1955
Many drugs which are alkylamines undergo dealkylation in the body. For example aminopyrine (2), ephedrine (3), codeine (4… Expand
  • table V
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