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Green chemistry for chemical synthesis
  • C. Li, B. Trost
  • Chemistry, Medicine
  • Proceedings of the National Academy of Sciences
  • 9 September 2008
Green chemistry for chemical synthesis addresses our future challenges in working with chemical processes and products by inventing novel reactions that can maximize the desired products and minimizeExpand
Atom Economy—A Challenge for Organic Synthesis: Homogeneous Catalysis Leads the Way
Enhancing the efficiency of the synthesis of complex organic products constitutes one of the most exciting challenges to the synthetic chemist. Increasing the catalogue of reactions that are simpleExpand
Applications of transition metal catalysis in drug discovery and development : an industrial perspective
Preface vii Contributors ix About the Authors xi 1 Transition Metal Catalysis in the Pharmaceutical Industry 1 Carl A. Busacca, Daniel R. Fandrick, Jinhua J. Song, and Chris H. Senanayake (BoehringerExpand
Asymmetric transition-metal-catalyzed allylic alkylations: applications in total synthesis.
Alkylations with Phenols, Nitrogen Nucleophiles in AAA Total Synthesis, and Considerations for Enantioselective Allylic Alkylation are presented. Expand
Asymmetric Transition Metal-Catalyzed Allylic Alkylations.
The focus of this review is on the area of enantioselective transition metal-catalyzed allylic alkylations which may involve C-C as well as C-X (X ) H or heteroatom) bond formation. Expand
Modern alkyne chemistry : catalytic and atom-economic transformations
Introduction PART I: CATALYTIC ISOMERIZATION OF ALKYNES 1) Redox Isomerization of Propargyl Alcohols to Enones 2) Carbophilic Cycloisomerization Reactions of Enynes and Domino Processes 3)Expand
Synthesis of a ring-expanded bryostatin analogue.
A ring-expanded bryostatin analogue was synthesized by utilizing a Ru-catalyzed tandem tetrahydropyran formation, a Pd-catalyzed tandem dihydropyran formation, and a ring-closing metathesis (RCM) asExpand
On inventing reactions for atom economy.
  • B. Trost
  • Chemistry, Medicine
  • Accounts of chemical research
  • 8 March 2002
Using mechanistic reasoning, over 20 new processes of varying complexity have been designed and implemented that involved C-C bond-forming reactions and the prospect for such developments is probed in the context of ruthenium-catalyzed reactions. Expand