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Receptors, Opioid, kappa

Known as: Receptors, kappa, kappa receptors, Receptors, kappa Opioid 
A class of opioid receptors recognized by its pharmacological profile. Kappa opioid receptors bind dynorphins with a higher affinity than endorphins… Expand
National Institutes of Health

Related topics

Related topics

12 relations
DynorphinsIn Bloodagonistsantagonists & inhibitors
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Broader (1)

Opioid Receptor

Narrower (4)

Ro1 protein, syntheticRo2 protein, recombinantkappa(1) opioid receptorkappa(2) opioid receptor

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Review
2018
Review
2018
Sex differences in neural mechanisms mediating reward and addiction
There is increasing evidence in humans and laboratory animals for biologically based sex differences in every phase of drug… Expand
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Review
2018
Review
2018
Opioid receptors: drivers to addiction?
Drug addiction is a worldwide societal problem and public health burden, and results from recreational drug use that develops… Expand
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Highly Cited
1994
Highly Cited
1994
Mu, delta, and kappa opioid receptor mRNA expression in the rat CNS: An in situ hybridization study
The μ, δ, and κ opioid receptors are the three main types of opioid receptors round in the central nervous system (CNS) and… Expand
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Highly Cited
1993
Highly Cited
1993
Cloning and functional comparison of kappa and delta opioid receptors from mouse brain.
While trying to identify new members of the somatostatin receptor family of G protein-coupled receptors, we isolated cDNAs from a… Expand
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Highly Cited
1992
Highly Cited
1992
Opioid and nonopioid components independently contribute to the mechanism of action of tramadol, an 'atypical' opioid analgesic.
Tramadol hydrochloride produced dose-related antinociception in mouse abdominal constriction [ED50 = 1.9 (1.2-2.6) mg/kg i.p… Expand
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Highly Cited
1989
Highly Cited
1989
Peripheral opioid receptors mediating antinociception in inflammation. Evidence for involvement of mu, delta and kappa receptors.
This study examined a possible peripheral site of action of opioids in the modulation of the response to noxious pressure on… Expand
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Highly Cited
1988
Highly Cited
1988
Autoradiographic differentiation of mu, delta and kappa opioid receptors in the rat forebrain and midbrain : A. Mansour H. Khachaturian, M.E. Lewis, H. Akil and S.J. Watson, Neuroscience, 7 (1987…
While there is an abundance of pharmacological and biochemical evidence to suggest the existence of multiple opioid receptors… Expand
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Highly Cited
1986
Highly Cited
1986
Psychotomimesis mediated by kappa opiate receptors
The kappa opioid agonists are analgesics that seem to be free of undesired morphine-like effects. Their dysphoric actions… Expand
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Highly Cited
1982
Highly Cited
1982
Dynorphin is a specific endogenous ligand of the kappa opioid receptor.
In the guinea pig ileum myenteric plexus--longitudinal muscle preparation, dynorphin-(1--13) and the prototypical kappa agonist… Expand
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Highly Cited
1976
Highly Cited
1976
The effects of morphine- and nalorphine- like drugs in the nondependent and morphine-dependent chronic spinal dog.
Three different syndromes produced by congeners of morphine have been identified in the nondependent chronic spinal dog. These… Expand
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