FAQ

Receptors, Islet Amyloid Polypeptide

Known as: IAPP Receptor, Receptor, IAPP, Amylin Receptor 
OBSOLETE. A G-protein coupled signalling receptor complex consisting of the calcitonin receptor and a receptor activity-modifying protein (RAMP… (More)
National Institutes of Health

Topic mentions per year

Topic mentions per year

1990-2016
01219902016

Related topics

Related topics

6 relations
In Bloodadministration & dosageantagonists & inhibitorsaspects of radiation effects
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Related mentions per year

Related mentions per year

1936-2018
19401960198020002020
Receptors, Islet Amyloid Polypeptide
physiological aspects
In Blood
antagonists & inhibitors
administration & dosage
aspects of radiation effects

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2017
2017
Amylin receptor ligands reduce the pathological cascade of Alzheimer's disease.
Amylin is an important gut-brain axis hormone. Since amylin and amyloid-β peptide (Aβ) share similar β sheet secondary structure… (More)
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2016
2016
Pramlintide Antagonizes Beta Amyloid (Aβ)- and Human Amylin-Induced Depression of Hippocampal Long-Term Potentiation
Accumulation of amyloid-β peptide (Aβ) is a pathological hallmark of Alzheimer’s disease (AD). We have previously demonstrated… (More)
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2016
2016
Mapping the calcitonin receptor in human brain stem.
The calcitonin receptor (CTR) is relevant to three hormonal systems: amylin, calcitonin, and calcitonin gene-related peptide… (More)
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2015
2015
Amylin Modulates the Mesolimbic Dopamine System to Control Energy Balance
Amylin acts in the CNS to reduce feeding and body weight. Recently, the ventral tegmental area (VTA), a mesolimbic nucleus… (More)
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2014
2014
Amylin Receptor Signaling in the Nucleus Accumbens Negatively Modulates μ-opioid-Driven Feeding
Amylin is a peptide co-secreted with insulin that penetrates into the brain, and produces satiation-like effects via actions in… (More)
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2013
2013
Amylin Receptor Signaling in the Ventral Tegmental Area is Physiologically Relevant for the Control of Food Intake
The ability of amylin, a pancreatic β-cell-derived neuropeptide, to promote negative energy balance has been ascribed to neural… (More)
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2013
2013
Amylin Receptor: A Common Pathophysiological Target in Alzheimer’s Disease and Diabetes Mellitus
Amylin (islet amyloid polypeptide) and amyloid-beta (Aβ) protein, which are deposited within pancreatic islets of diabetics and… (More)
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2004
2004
Brief Communication Antagonist of the Amylin Receptor Blocks -Amyloid Toxicity in Rat Cholinergic Basal Forebrain Neurons
Salvage of cholinergic neurons in the brain through a blockade of the neurotoxic effects of amyloid protein (A ) is one of the… (More)
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2000
2000
The constitutive secretory pathway is a major route for islet amyloid polypeptide secretion in neonatal but not adult rat islet cells.
Islet amyloid polypeptide (IAPP or amylin) is a normal secretory product of the pancreatic beta-cell that is cosecreted with… (More)
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Highly Cited
1999
Highly Cited
1999
An Amylin Receptor Is Revealed Following Co-Transfection of a Calcitonin Receptor with Receptor Activity Modifying Proteins-1 or -3.
Human receptor activity modifying proteins (RAMP) regulate the ligand specificity of the calcitonin-receptor-like-receptor… (More)
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