Receptors, Islet Amyloid Polypeptide
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Amylin is an important gut-brain axis hormone. Since amylin and amyloid-β peptide (Aβ) share similar β sheet secondary structure… (More)
- Molecular Neurobiology
Accumulation of amyloid-β peptide (Aβ) is a pathological hallmark of Alzheimer’s disease (AD). We have previously demonstrated… (More)
The calcitonin receptor (CTR) is relevant to three hormonal systems: amylin, calcitonin, and calcitonin gene-related peptide… (More)
Amylin acts in the CNS to reduce feeding and body weight. Recently, the ventral tegmental area (VTA), a mesolimbic nucleus… (More)
Amylin is a peptide co-secreted with insulin that penetrates into the brain, and produces satiation-like effects via actions in… (More)
The ability of amylin, a pancreatic β-cell-derived neuropeptide, to promote negative energy balance has been ascribed to neural… (More)
- Front. Aging Neurosci.
Amylin (islet amyloid polypeptide) and amyloid-beta (Aβ) protein, which are deposited within pancreatic islets of diabetics and… (More)
Salvage of cholinergic neurons in the brain through a blockade of the neurotoxic effects of amyloid protein (A ) is one of the… (More)
Islet amyloid polypeptide (IAPP or amylin) is a normal secretory product of the pancreatic beta-cell that is cosecreted with… (More)
Human receptor activity modifying proteins (RAMP) regulate the ligand specificity of the calcitonin-receptor-like-receptor… (More)