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Receptors, Interleukin-1

Known as: Receptors, IL1, IL1 Receptors, IL 1 Receptors 
Cell surface receptors that are specific for INTERLEUKIN-1. Included under this heading are signaling receptors, non-signaling receptors and… 
National Institutes of Health

Related topics

Related topics

12 relations
IL1R1 geneIn BloodInterleukin 1 Receptor Antagonist ProteinInterleukin-1

Narrower (3)

TIGIRR-1 receptorTIRAP protein, humanTIRAP protein, mouse

Papers overview

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Highly Cited
2006
Highly Cited
2006
Smad6 negatively regulates interleukin 1-receptor–Toll-like receptor signaling through direct interaction with the adaptor Pellino-1
Transforming growth factor-β1 (TGF-β1) is a potent cytokine with pleiotropic effects, including anti-inflammatory activity. Here… 
Highly Cited
2006
Highly Cited
2006
Association of β-arrestin and TRAF6 negatively regulates Toll-like receptor–interleukin 1 receptor signaling
Tumor necrosis factor receptor–associated factor 6 (TRAF6) is critical for mediating Toll-like receptor (TLR)–interleukin 1… 
Highly Cited
2002
Highly Cited
2002
Expression of interleukin‐1 receptors and their role in interleukin‐1 actions in murine microglial cells
Interleukin (IL)‐1 is an important mediator of acute brain injury and inflammation, and has been implicated in chronic… 
Review
2000
Review
2000
Biological role of interleukin 1 receptor antagonist isoforms
The interleukin 1 receptor antagonist (IL1Ra) family of molecules now includes one secreted isoform (sIL1Ra) and three… 
Highly Cited
1997
Highly Cited
1997
Interleukin-1 receptor and receptor antagonist gene expression after focal stroke in rats.
BACKGROUND AND PURPOSE The expression of interleukin-1 beta (IL-1 beta) is upregulated after focal brain ischemia, and previous… 
Review
1994
Review
1994
The biological properties of interleukin-1.
Interleukin-1 (IL-1) is primarily an inflammatory cytokine. Biologically, IL-1 is more closely related to tumor necrosis factor… 
Highly Cited
1992
Highly Cited
1992
Coordinated antiinflammatory effects of interleukin 4: interleukin 4 suppresses interleukin 1 production but up-regulates gene expression and synthesis of interleukin 1 receptor antagonist.
Interleukin 1 receptor antagonist (IL-1ra), a naturally occurring polypeptide with amino acid sequence homology to interleukin 1… 
Highly Cited
1990
Highly Cited
1990
Transforming growth factor beta is a potent inhibitor of interleukin 1 (IL-1) receptor expression: proposed mechanism of inhibition of IL-1 action
Transforming growth factor beta (TGF-beta) acts as a potent inhibitor of the growth and functions of lymphoid and hemopoietic… 
Highly Cited
1989
Highly Cited
1989
Two high-affinity interleukin 1 receptors represent separate gene products.
Interleukin 1 (IL-1) is a polypeptide hormone that mediates a broad range of biological activities and interacts with surface… 
Highly Cited
1988
Highly Cited
1988
Induction of high-affinity interleukin 1 receptor on human peripheral blood lymphocytes by glucocorticoid hormones
The in vitro effect of glucocorticoids (GCs) on IL-1-R expression of human PBMCs was investigated. Both physiological and… 
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