Interleukin 1 Receptor Antagonist Protein

Known as: Interleukin 1 Inhibitor, Urine, IL1 Inhibitor, Urine-Derived, Urine-Derived IL1 Inhibitor 
A ligand that binds to but fails to activate the INTERLEUKIN 1 RECEPTOR. It plays an inhibitory role in the regulation of INFLAMMATION and FEVER… (More)
National Institutes of Health

Papers overview

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Review
2010
Review
2010
The interleukin-1 (IL-1) family of cytokines comprises 11 proteins (IL-1F1 to IL-1F11) encoded by 11 distinct genes in humans and… (More)
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Highly Cited
2005
Highly Cited
2005
Cytokines of the interleukin-1 (IL-1) family, such as IL-1 alpha/beta and IL-18, have important functions in host defense, immune… (More)
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Highly Cited
2000
Highly Cited
2000
Interleukin (IL)-1 is a proinflammatory cytokine that plays important roles in inflammation, host defense, and the neuro-immuno… (More)
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Highly Cited
2000
Highly Cited
2000
Hypoxic pulmonary vasoconstriction is associated with but may not be sufficient for the development of high-altitude pulmonary… (More)
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Review
1998
Review
1998
The interleukin-1 receptor antagonist (IL-1Ra) is a member of the IL-1 family that binds to IL-1 receptors but does not induce… (More)
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Review
1998
Review
1998
IL-1 (IL-1 alpha or IL-1 beta) is the prototypic "multifunctional" cytokine. Unlike the lymphocyte and colony stimulating growth… (More)
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Highly Cited
1998
Highly Cited
1998
OBJECTIVE To evaluate the efficacy and safety of interleukin-1 receptor antagonist (IL-1Ra) in patients with rheumatoid arthritis… (More)
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Highly Cited
1995
Highly Cited
1995
Elevated plasma levels of interleukin-6 (IL-6), a key regulator of the acute phase response that includes increased fibrinogen… (More)
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Review
1993
Review
1993
IL-1ra is the first described naturally occurring receptor antagonist of any cytokine or hormone-like molecule. IL-1ra is a… (More)
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Highly Cited
1990
Highly Cited
1990
Human monocytes induced with adherent IgG secrete an interleukin-1 receptor antagonist which could be important for the in vivo… (More)
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