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Interleukin 1 Receptor Antagonist Protein

Known as: Interleukin 1 Inhibitor, Urine, IL1 Inhibitor, Urine-Derived, Urine-Derived IL1 Inhibitor 
A ligand that binds to but fails to activate the INTERLEUKIN 1 RECEPTOR. It plays an inhibitory role in the regulation of INFLAMMATION and FEVER… 
National Institutes of Health

Related topics

Related topics

23 relations

Broader (1)

Antirheumatic Agents

Narrower (7)

AntrilIL-1ra-Fc-IL-18bp fusion proteinIL1RN protein, humanINTERLEUKIN 1 RECEPTOR ANTAGONIST DEFICIENCY
IL1RN geneIL1RN wt AlleleIn BloodInterleukin 1 Receptor Antagonist Measurement

Papers overview

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Highly Cited
2003
Highly Cited
2003
The EAE-associated behavioral syndrome II. Modulation by anti-inflammatory treatments
Highly Cited
2001
Highly Cited
2001
Production of IL‐1 receptor antagonist by hepatocytes is regulated as an acute‐phase protein in vivo
IL‐1 receptor antagonist (IL‐1Ra) is produced by isolated human hepatocytes with characteristics of an acute‐phase protein. There… 
Highly Cited
2000
Highly Cited
2000
Smoking and GCF levels of IL-1beta and IL-1ra in periodontal disease.
AIMS GCF levels of the cytokine IL-1beta and its receptor antagonist IL-1ra were analyzed with respect to smoking in patients… 
Highly Cited
1999
Highly Cited
1999
Immunohistochemical localization of interleukin-1β, interleukin-1 receptor antagonist and interleukin-1β converting enzyme/caspase-1 in the rat brain after peripheral administration of kainic acid
Highly Cited
1998
Highly Cited
1998
Interleukin-1 receptor antagonist suppresses experimental autoimmune encephalomyelitis (EAE) in rats by influencing the activation and proliferation of encephalitogenic cells
Highly Cited
1994
Highly Cited
1994
Grain dust-induced airflow obstruction and inflammation of the lower respiratory tract.
To investigate the relationship between the physiologic and biologic effects of grain dust inhalation, we exposed 15 nonsmoking… 
Highly Cited
1993
Highly Cited
1993
Treatment With an Interleukin-1 Receptor Antagonist Protein Prolongs Mouse Islet Allograft Survival
An interleukin-1 receptor antagonist protein was evaluated with regard to its efficacy in allogeneic and xenogeneic islet… 
Highly Cited
1993
Highly Cited
1993
Expression of interleukin‐1 receptor antagonist (IL‐1ra) by human circulating polymorphonuclear cells
After appropriate stimulation, mononuclear phagocytes express a specific inhibitor of interleukin (IL)‐1, now re‐named IL‐1… 
Highly Cited
1992
Highly Cited
1992
Endotoxin-induced cytokine gene expression in vivo. IV. Expression of interleukin-1 alpha/beta and interleukin-1 receptor antagonist mRNA during endotoxemia and during endotoxin-initiated local acute…
After the intravenous (IV) injection of endotoxin, (lipopolysaccharide [LPS]), in the rat, interleukin-1 alpha/beta (IL-1 alpha… 
Highly Cited
1991
Highly Cited
1991
Peripheral nerve regeneration is impeded by interleukin‐1 receptor antagonist released from a polymeric guidance channel
Interleukin‐1 receptor antagonist (IL‐lra), a true antagonist of the interleukin‐1 (IL‐1) receptors, is released by activated… 
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