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IL1RN protein, human

Known as: IL-1RN, ICIL-1RA protein, human, Intracellular IL-1 Receptor Antagonist Type II 
Interleukin-1 receptor antagonist protein (177 aa, ~20 kDa) is encoded by the human IL1RN gene. This protein is involved in the inhibition of the… 
National Institutes of Health

Related topics

Related topics

11 relations
Cytokine GeneCytokine Receptor BindingCytokine SignalingCytoplasm

Broader (1)

Interleukin 1 Receptor Antagonist Protein

Papers overview

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Highly Cited
2005
Highly Cited
2005
Discovering reliable protein interactions from high-throughput experimental data using network topology
1999
1999
Intracellular IL-1 receptor antagonist is elevated in human dermal fibroblasts that overexpress intracellular precursor IL-1 alpha.
Cultured dermal fibroblasts from systemic sclerosis patients express higher levels of intracellular IL-1 alpha than fibroblasts… 
1999
1999
Ovarian interleukin-1 receptor antagonist in rats: gene expression, cellular localization, cyclic variation, and hormonal regulation of a potential determinant of interleukin-1 action.
It is hypothesized that the intraovarian interleukin (IL)-1 system plays a prominent role in the regulation of follicular… 
1998
1998
Increased intracellular sequestration of the insulin-regulated aminopeptidase upon differentiation of 3T3-L1 cells.
In fat and muscle cells, the glucose transporter GLUT4 is sequestered in an intracellular compartment under basal conditions and… 
Highly Cited
1997
Highly Cited
1997
Trafficking kinetics of the insulin-regulated membrane aminopeptidase in 3T3-L1 adipocytes.
In fat and muscle cells insulin causes the marked translocation of the glucose transporter GLUT4 from its intracellular location… 
Highly Cited
1996
Highly Cited
1996
Circulating serum levels of IL-1ra in patients with relapsing remitting multiple sclerosis are normal during remission phases but significantly increased either during exacerbations or in response to…
Interleukin (IL)-1 receptor antagonist (IL-1ra) is a naturally occurring inhibitor of IL-1 which binds to IL-1 receptors without… 
1995
1995
Synthesis and secretion of interleukin-1 alpha and interleukin-1 receptor antagonist during differentiation of cultured keratinocytes.
Keratinocytes produce interleukin-1 alpha (IL-1 alpha) and the epithelial variant of its inhibitor, interleukin-1 receptor… 
1993
1993
Potential agonist action of the interleukin-1 receptor antagonist protein: implications for treatment of women.
The interleukin-1 receptor antagonist protein (IRAP) caused a concentration-related increase in prostaglandin production by human… 
1992
1992
Expression and regulation of human alveolar macrophage-derived interleukin-1 receptor antagonist.
The alveolar macrophage (AM) is the sentinel immune cell of the distal airspace of the lung. These mononuclear phagocytic cells… 
Review
1991
Review
1991
The biological role of naturally-occurring cytokine inhibitors.
Four different mechanisms of cytokine inhibition might be involved in regulation of cytokine effects in vivo. Different cytokines… 
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