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IL1RN gene

Known as: IL-1RN, INTERLEUKIN 1 RECEPTOR ANTAGONIST, MGC10430 
This gene is involved in the inhibition of signaling.
National Institutes of Health

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Cytokine Receptor BindingCytokine SignalingIL1R1 geneIL1R1 wt Allele

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IL1RN wt Allele

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2009
2009
Haplotypes of the interleukin-1 receptor antagonist gene, interleukin-1 receptor antagonist mRNA levels and the risk of myocardial infarction.
2008
2008
Role of host interleukin 1β gene (IL-1B) and interleukin 1 receptor antagonist gene (IL-1RN) polymorphisms in clinical outcomes in Helicobacter pylori-positive Turkish patients with dyspepsia
BackgroundHelicobacter pylori infection leads to different clinical outcomes depending on both host and bacterial factors. In a… 
2007
2007
MIC1 and IL1RN Genetic Variation and Advanced Prostate Cancer Risk
Recently, polymorphisms in macrophage inhibitory cytokine-1 ( MIC1 ) and interleukin 1 receptor antagonist ( IL1RN ) were… 
2006
2006
Interleukin-1β gene (IL-1B) and interleukin 1 receptor antagonist gene (IL-1RN) polymorphisms and gastric cancer risk in an Omani Arab population
BackgroundGastric cancer (GC) is the most common malignancy in Oman. Interleukin-1β gene (IL-1B) and interleukin-1 receptor… 
2003
2003
Mice transgenic for intracellular interleukin‐1 receptor antagonist type 1 are protected from collagen‐induced arthritis
Interleukin‐1 receptor antagonist (IL‐1Ra) is a natural IL‐1 inhibitor, which competitively inhibits binding of IL‐1 to its… 
Highly Cited
2000
Highly Cited
2000
Genetic factors determine extent of bone loss in inflammatory bowel disease.
BACKGROUND & AIMS Although bone loss and osteoporosis are well-known long-term sequelae of inflammatory bowel disease (IBD), the… 
Highly Cited
1999
Highly Cited
1999
Relevance of interleukin 1 receptor antagonist intron 2 polymorphism in Italian MS patients
Article abstract The A1/A1 genotype of the anti-inflammatory cytokine interleukin 1 receptor antagonist (IL-1Ra) polymorphism was… 
Highly Cited
1993
Highly Cited
1993
Treatment With an Interleukin-1 Receptor Antagonist Protein Prolongs Mouse Islet Allograft Survival
An interleukin-1 receptor antagonist protein was evaluated with regard to its efficacy in allogeneic and xenogeneic islet… 
1993
1993
Increased fibrinogen synthesis in mice during the acute phase response: co-operative interaction of interleukin 1, interleukin 6, and interleukin 1 receptor antagonist.
1993
1993
Recombinant interleukin-1 receptor antagonist protein prevents sensitization and intestinal anaphylaxis in guinea pigs.
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