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IL1RN wt Allele

Known as: Interleukin 1 Receptor Antagonist wt Allele, IL-1RN, MGC10430 
Human IL1RN wild-type allele is located in the vicinity of 2q14.2 and is approximately 27 kb in length. This allele, which encodes interleukin-1… Expand
National Institutes of Health

Related topics

Related topics

9 relations
Cytokine Receptor BindingCytokine SignalingIL1R Signaling PathwayIntercellular Communication Process
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Broader (1)

IL1RN gene

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2016
Highly Cited
2016
Blood–brain barrier breakdown promotes macrophage infiltration and cognitive impairment in leptin receptor-deficient mice
Accumulating evidence indicates that obesity accelerates the onset of cognitive decline. While mechanisms are still being… Expand
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Highly Cited
2015
Highly Cited
2015
IL-1β, IL-6 and IL1Ra levels in temporal lobe epilepsy
PURPOSE There is now extensive evidence to support the involvement of inflammation in the course of epileptic seizures. Seizure… Expand
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Review
2014
Review
2014
IL-1 blockade in autoinflammatory syndromes.
Monogenic autoinflammatory syndromes present with excessive systemic inflammation including fever, rashes, arthritis, and organ… Expand
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Highly Cited
2013
Highly Cited
2013
Deficiency of Interleukin‐1 Receptor Antagonist Responsive to Anakinra
Abstract:  We describe a 3‐month‐old infant who presented to our institution with interleukin (IL)‐1 receptor antagonist… Expand
Highly Cited
2012
Highly Cited
2012
Principal Component Analysis of the Cytokine and Chemokine Response to Human Traumatic Brain Injury
There is a growing realisation that neuro-inflammation plays a fundamental role in the pathology of Traumatic Brain Injury (TBI… Expand
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Highly Cited
2010
Highly Cited
2010
Inflammation induced by LPS enhances epileptogenesis in immature rat and may be partially reversed by IL1RA
Inflammatory signaling in the central nervous system (CNS) has been shown to exacerbate both seizure activity and seizure‐induced… Expand
Highly Cited
2010
Highly Cited
2010
IRAP and REMAP assessments of genetic similarity in rice
Rice is a model genome for cereal research, providing important information about genome structure and evolution… Expand
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Highly Cited
2010
Highly Cited
2010
Role of Host Immune Response and Viral Load in the Differential Outcome of Pandemic H1N1 (2009) Influenza Virus Infection in Indian Patients
Background An unusually high number of severe pneumonia cases with considerable mortality is being observed with the pandemic… Expand
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Highly Cited
2009
Highly Cited
2009
An autoinflammatory disease with deficiency of the interleukin-1-receptor antagonist.
BACKGROUND Autoinflammatory diseases manifest inflammation without evidence of infection, high-titer autoantibodies, or… Expand
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Highly Cited
1991
Highly Cited
1991
Interleukin-1 is cytoprotective, antisecretory, stimulates PGE2 synthesis by the stomach, and retards gastric emptying.
Human recombinant interleukin 1 beta (IL-1) administered intraperitoneally to rats produced the following gastric effects: 1. It… Expand
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