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IL1RN wt Allele
Known as:
Interleukin 1 Receptor Antagonist wt Allele
, IL-1RN
, MGC10430
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Human IL1RN wild-type allele is located in the vicinity of 2q14.2 and is approximately 27 kb in length. This allele, which encodes interleukin-1…
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National Institutes of Health
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Related topics
Related topics
9 relations
Cytokine Receptor Binding
Cytokine Signaling
IL1R Signaling Pathway
Intercellular Communication Process
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Broader (1)
IL1RN gene
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2016
Highly Cited
2016
Blood–brain barrier breakdown promotes macrophage infiltration and cognitive impairment in leptin receptor-deficient mice
A. Stranahan
,
Shuai Hao
,
Aditi Dey
,
Xiaolin Yu
,
B. Baban
Journal of Cerebral Blood Flow and Metabolism
2016
Corpus ID: 25696475
Accumulating evidence indicates that obesity accelerates the onset of cognitive decline. While mechanisms are still being…
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Highly Cited
2015
Highly Cited
2015
IL-1β, IL-6 and IL1Ra levels in temporal lobe epilepsy
I. Uludag
,
T. Duksal
,
B. I. Tiftikçioğlu
,
Y. Zorlu
,
Feriha Ozkaya
,
G. Kırkalı
Seizure
2015
Corpus ID: 15991547
Review
2014
Review
2014
IL-1 blockade in autoinflammatory syndromes.
A. A. Jesus
,
R. Goldbach-Mansky
Annual Review of Medicine
2014
Corpus ID: 207653838
Monogenic autoinflammatory syndromes present with excessive systemic inflammation including fever, rashes, arthritis, and organ…
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Highly Cited
2013
Highly Cited
2013
Deficiency of Interleukin‐1 Receptor Antagonist Responsive to Anakinra
Charlotte Schnellbacher
,
Giovanna Ciocca
,
+4 authors
R. Rivas-Chacón
Pediatric dermatology
2013
Corpus ID: 27291226
Abstract: We describe a 3‐month‐old infant who presented to our institution with interleukin (IL)‐1 receptor antagonist…
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Highly Cited
2012
Highly Cited
2012
DIRA, DITRA, and new insights into pathways of skin inflammation: what's in a name?
E. Cowen
,
R. Goldbach-Mansky
Archives of Dermatology
2012
Corpus ID: 2625703
Dermatology has a long-standing affinity for acronyms. From AGEP (acute generalized exanthematous pustulosis) to XP (xeroderma…
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Highly Cited
2010
Highly Cited
2010
Inflammation induced by LPS enhances epileptogenesis in immature rat and may be partially reversed by IL1RA
S. Auvin
,
Don Shin
,
A. Mazarati
,
R. Sankar
Epilepsia
2010
Corpus ID: 23448868
Inflammatory signaling in the central nervous system (CNS) has been shown to exacerbate both seizure activity and seizure‐induced…
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Highly Cited
2010
Highly Cited
2010
IRAP and REMAP assessments of genetic similarity in rice
C. Branco
,
E. A. Vieira
,
+6 authors
C. A. Oliveira
Journal of Applied Genetics
2010
Corpus ID: 23308719
Rice is a model genome for cereal research, providing important information about genome structure and evolution…
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Highly Cited
2010
Highly Cited
2010
Role of Host Immune Response and Viral Load in the Differential Outcome of Pandemic H1N1 (2009) Influenza Virus Infection in Indian Patients
V. Arankalle
,
K. Lole
,
+5 authors
D. Kadam
PLoS ONE
2010
Corpus ID: 13471086
Background An unusually high number of severe pneumonia cases with considerable mortality is being observed with the pandemic…
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Highly Cited
2009
Highly Cited
2009
An autoinflammatory disease with deficiency of the interleukin-1-receptor antagonist.
I. Aksentijevich
,
S. Masters
,
+39 authors
R. Goldbach-Mansky
New England Journal of Medicine
2009
Corpus ID: 205090506
BACKGROUND Autoinflammatory diseases manifest inflammation without evidence of infection, high-titer autoantibodies, or…
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Highly Cited
1991
Highly Cited
1991
Interleukin-1 is cytoprotective, antisecretory, stimulates PGE2 synthesis by the stomach, and retards gastric emptying.
A. Robert
,
A. S. Olafsson
,
C. Lancaster
,
W. R. Zhang
Life Science
1991
Corpus ID: 34221581
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