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Receptors, Death Domain

Known as: Receptors, DR Family, DR Family Receptors, Receptors, Death Domain [Chemical/Ingredient] 
A family of cell surface receptors that signal via a conserved domain that extends into the cell CYTOPLASM. The conserved domain is referred to as a… Expand
National Institutes of Health

Papers overview

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Review
2018
Review
2018
The pathogenesis of non-alcoholic fatty liver disease, particularly the mechanisms whereby a minority of patients develop a more… Expand
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Review
2017
Review
2017
Roles for cell death in development, homeostasis, and the control of infections and cancer have long been recognized. Although… Expand
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Review
2016
Review
2016
Reactive oxygen species (ROS) are short-lived and highly reactive molecules. The generation of ROS in cells exists in equilibrium… Expand
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Review
2016
Review
2016
Apoptosis is a form of programmed cell death that results in the orderly and efficient removal of damaged cells, such as those… Expand
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Review
2015
Review
2015
Resistance to chemotherapeutic drugs is the major hindrance in the successful cancer therapy. The tumor necrosis factor-related… Expand
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Review
2002
Review
2002
Cancer cells often develop resistance to chemotherapy or irradiation through mutations in the p53 tumour-suppressor gene, which… Expand
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Review
2001
Review
2001
Nuclear DNA damage and ligation of plasma-membrane death receptors have long been recognized as initial triggers of apoptosis… Expand
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Review
1999
Review
1999
The death receptors Fas and tumor necrosis factor receptor 1 (TNFR1) trigger apoptosis upon engagement by their cognate death… Expand
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Review
1998
Review
1998
Apoptosis is a cell suicide mechanism that enables metazoans to control cell number in tissues and to eliminate individual cells… Expand
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Highly Cited
1998
Highly Cited
1998
We report here the purification of a cytosolic protein that induces cytochrome c release from mitochondria in response to caspase… Expand
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