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Tumor Necrosis Factor Receptor

Known as: Tumor Necrosis Factor Receptors, Receptors, TNF, receptors tnf 
Members of the tumor necrosis factor receptor (TNFR) family play a key role in regulating the immune response to infection. They are cell-surface… 
National Institutes of Health

Related topics

Related topics

30 relations
Apoptosis Regulatory ProteinsCytokine Receptor GeneCytokine Signaling ProcessIn Blood

Narrower (9)

BLyS receptorCrmE protein, Vaccinia virusRELTReceptors, Tumor Necrosis Factor, Type II

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Review
2011
Review
2011
Signaling by the tumor necrosis factor receptor superfamily in B‐cell biology and disease
Summary:  Members of the tumor necrosis factor receptor superfamily (TNFRSF) participate prominently in B‐cell maturation and… 
Highly Cited
2009
Highly Cited
2009
Divergent Tumor Necrosis Factor Receptor-Related Remodeling Responses in Heart Failure: Role of Nuclear Factor-&kgr;B and Inflammatory Activation
Background— Although preclinical data suggested that tumor necrosis factor-&agr; (TNF) neutralization in heart failure (HF) would… 
Highly Cited
2006
Highly Cited
2006
Site-specific Lys-63-linked Tumor Necrosis Factor Receptor-associated Factor 6 Auto-ubiquitination Is a Critical Determinant of IκB Kinase Activation*
Tumor necrosis factor (TNF) receptor-associated factor 6 (TRAF6) is a key mediator in proximal signaling of the interleukin-1… 
Highly Cited
2003
Highly Cited
2003
Activation signal of nuclear factor-kappa B in response to endoplasmic reticulum stress is transduced via IRE1 and tumor necrosis factor receptor-associated factor 2.
Conditions that perturb the function of the endoplasmic reticulum (ER) lead to an accumulation of proteins and subsequent… 
Highly Cited
1998
Highly Cited
1998
Characterization of the intracellular domain of receptor activator of NF-kappaB (RANK). Interaction with tumor necrosis factor receptor-associated factors and activation of NF-kappab and c-Jun N…
Various members of the tumor necrosis factor (TNF) receptor superfamily interact directly with signaling molecules of the TNF… 
Highly Cited
1997
Highly Cited
1997
p55 Tumor Necrosis Factor Receptor Fusion Protein in the Treatment of Patients With Severe Sepsis and Septic Shock: A Randomized Controlled Multicenter Trial
Objective. —To evaluate the safety and efficacy of p55 tumor necrosis factor receptor fusion protein, a recombinant chimeric… 
Highly Cited
1995
Highly Cited
1995
Fas- and Tumor Necrosis Factor-induced Apoptosis Is Inhibited by the Poxvirus crmA Gene Product (*)
crmA is a cowpox virus gene that encodes a protease inhibitor of the serpin family. The only reported target for the CrmA protein… 
Highly Cited
1995
Highly Cited
1995
Identification of a Protein with Homology to hsp90 That Binds the Type 1 Tumor Necrosis Factor Receptor (*)
The yeast-based two hybrid has been used to identify a novel protein that binds to the intracellular domain of the type 1… 
Review
1994
Review
1994
Tumor necrosis factor receptor-mediated signaling pathways
T UMOR necrosis factor c~ (TNF) ~ and tumor necrosis factor ~ (lymphotoxin) are two cytokines produced primarily by macrophages… 
Highly Cited
1987
Highly Cited
1987
Immunoregulatory activity of recombinant human tumor necrosis factor (TNF)-alpha: induction of TNF receptors on human T cells and TNF-alpha-mediated enhancement of T cell responses.
The expression of specific tumor necrosis factor (TNF) membrane receptors and biological effects of recombinant TNF (rTNF)-alpha… 
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