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Tumor Necrosis Factor Receptor
Known as:
Tumor Necrosis Factor Receptors
, Receptors, TNF
, receptors tnf
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Members of the tumor necrosis factor receptor (TNFR) family play a key role in regulating the immune response to infection. They are cell-surface…
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National Institutes of Health
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Related topics
Related topics
30 relations
Apoptosis Regulatory Proteins
Cytokine Receptor Gene
Cytokine Signaling Process
In Blood
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Narrower (9)
BLyS receptor
CrmE protein, Vaccinia virus
RELT
Receptors, Tumor Necrosis Factor, Type II
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Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
Review
2001
Review
2001
Toll-like receptors: critical proteins linking innate and acquired immunity
S. Akira
,
K. Takeda
,
T. Kaisho
Nature Immunology
2001
Corpus ID: 639653
Recognition of pathogens is mediated by a set of germline-encoded receptors that are referred to as pattern-recognition receptors…
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Review
2001
Review
2001
The TNF and TNF Receptor Superfamilies Integrating Mammalian Biology
R. Locksley
,
N. Killeen
,
M. Lenardo
Cell
2001
Corpus ID: 7657797
Review
1999
Review
1999
Modulation of osteoclast differentiation and function by the new members of the tumor necrosis factor receptor and ligand families.
T. Suda
,
N. Takahashi
,
N. Udagawa
,
E. Jimi
,
M. Gillespie
,
T. Martin
Endocrine reviews
1999
Corpus ID: 12520836
Osteoblasts/stromal cells are essentially involved in osteoclast differentiation and function through cell-to-cell contact (Fig…
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Highly Cited
1999
Highly Cited
1999
Tumor necrosis factor receptor family member RANK mediates osteoclast differentiation and activation induced by osteoprotegerin ligand.
H. Hsu
,
D. Lacey
,
+18 authors
W. Boyle
Proceedings of the National Academy of Sciences…
1999
Corpus ID: 2824245
A receptor that mediates osteoprotegerin ligand (OPGL)-induced osteoclast differentiation and activation has been identified via…
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Highly Cited
1999
Highly Cited
1999
A trial of etanercept, a recombinant tumor necrosis factor receptor:Fc fusion protein, in patients with rheumatoid arthritis receiving methotrexate.
M. Weinblatt
,
J. Kremer
,
+6 authors
D. Burge
New England Journal of Medicine
1999
Corpus ID: 2488370
BACKGROUND Patients treated with methotrexate for rheumatoid arthritis often improve but continue to have active disease. This…
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Highly Cited
1997
Highly Cited
1997
Treatment of rheumatoid arthritis with a recombinant human tumor necrosis factor receptor (p75)-Fc fusion protein.
L. Moreland
,
S. Baumgartner
,
+9 authors
C. Blosch
New England Journal of Medicine
1997
Corpus ID: 28123547
BACKGROUND Tumor necrosis factor (TNF) is a proinflammatory cytokine involved in the pathogenesis of rheumatoid arthritis, and…
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Highly Cited
1997
Highly Cited
1997
Initiation of liver growth by tumor necrosis factor: deficient liver regeneration in mice lacking type I tumor necrosis factor receptor.
Y. Yamada
,
I. Kirillova
,
J. Peschon
,
N. Fausto
Proceedings of the National Academy of Sciences…
1997
Corpus ID: 1302377
The mechanisms that initiate liver regeneration after resection of liver tissue are not known. To determine whether cytokines are…
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Highly Cited
1997
Highly Cited
1997
TRANCE Is a Novel Ligand of the Tumor Necrosis Factor Receptor Family That Activates c-Jun N-terminal Kinase in T Cells*
B. Wong
,
J. Rho
,
+9 authors
Yongwon Choi
Journal of Biological Chemistry
1997
Corpus ID: 44616461
A novel member of the tumor necrosis factor (TNF) cytokine family, designated TRANCE, was cloned during a search for apoptosis…
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Highly Cited
1996
Highly Cited
1996
Treatment of septic shock with the tumor necrosis factor receptor:Fc fusion protein. The Soluble TNF Receptor Sepsis Study Group.
C. Fisher
,
J. Agosti
,
+6 authors
E. Benjamin
New England Journal of Medicine
1996
Corpus ID: 36962536
BACKGROUND A recombinant, soluble fusion protein that is a dimer of an extracellular portion of the human tumor necrosis factor…
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Highly Cited
1996
Highly Cited
1996
Tumor Necrosis Factor-α and Tumor Necrosis Factor Receptors in the Failing Human Heart
G. Torre-Amione
,
S. Kapadia
,
+4 authors
D. Mann
1996
Corpus ID: 72067998
Background Tumor necrosis factor-α (TNF-α) is a proinflammatory cytokine that produces negative inotropic effects in the heart…
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