Tumor Necrosis Factor Receptor

Known as: Tumor Necrosis Factor Receptors, Receptors, TNF, receptors tnf 
Members of the tumor necrosis factor receptor (TNFR) family play a key role in regulating the immune response to infection. They are cell-surface… (More)
National Institutes of Health

Related topics

Related topics

27 relations
Apoptosis Regulatory ProteinsCytokine Receptor GeneCytokine Signaling ProcessIn Blood
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Narrower (6)

BLyS receptorRELTReceptors, Tumor Necrosis Factor, Type IITNFRSF12A protein
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Papers overview

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Review
2017
Review
2017
A review on the evolution of PD-1/PD-L1 immunotherapy for bladder cancer: The future is now.
The treatment of bladder cancer has evolved over time to encompass not only the traditional modalities of chemotherapy and… (More)
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Review
2001
Review
2001
Toll-like receptors: critical proteins linking innate and acquired immunity
Recognition of pathogens is mediated by a set of germline-encoded receptors that are referred to as pattern-recognition receptors… (More)
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Review
1999
Review
1999
Modulation of osteoclast differentiation and function by the new members of the tumor necrosis factor receptor and ligand families.
Osteoblasts/stromal cells are essentially involved in osteoclast differentiation and function through cell-to-cell contact (Fig… (More)
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Highly Cited
1999
Highly Cited
1999
Tumor necrosis factor receptor family member RANK mediates osteoclast differentiation and activation induced by osteoprotegerin ligand.
A receptor that mediates osteoprotegerin ligand (OPGL)-induced osteoclast differentiation and activation has been identified via… (More)
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Highly Cited
1999
Highly Cited
1999
A trial of etanercept, a recombinant tumor necrosis factor receptor:Fc fusion protein, in patients with rheumatoid arthritis receiving methotrexate.
BACKGROUND Patients treated with methotrexate for rheumatoid arthritis often improve but continue to have active disease. This… (More)
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Highly Cited
1997
Highly Cited
1997
Treatment of rheumatoid arthritis with a recombinant human tumor necrosis factor receptor (p75)-Fc fusion protein.
BACKGROUND Tumor necrosis factor (TNF) is a proinflammatory cytokine involved in the pathogenesis of rheumatoid arthritis, and… (More)
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Highly Cited
1997
Highly Cited
1997
TRANCE is a novel ligand of the tumor necrosis factor receptor family that activates c-Jun N-terminal kinase in T cells.
A novel member of the tumor necrosis factor (TNF) cytokine family, designated TRANCE, was cloned during a search for apoptosis… (More)
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Highly Cited
1995
Highly Cited
1995
The transmembrane form of tumor necrosis factor is the prime activating ligand of the 80 kDa tumor necrosis factor receptor
The 60 kDa tumor necrosis factor receptor (TNFR60) is regarded as the major signal transducer of TNF-induced cellular responses… (More)
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Highly Cited
1995
Highly Cited
1995
The Epstein-Barr virus transforming protein LMP1 engages signaling proteins for the tumor necrosis factor receptor family
The cytoplasmic C-terminus of Epstein-Barr virus (EBV) latent infection membrane protein 1 (LMP1) is essential for B lymphocyte… (More)
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Highly Cited
1994
Highly Cited
1994
Reduced tyrosine kinase activity of the insulin receptor in obesity-diabetes. Central role of tumor necrosis factor-alpha.
Insulin resistance is an important metabolic abnormality often associated with infections, cancer, obesity, and especially non… (More)
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