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Tumor Necrosis Factor Receptor

Known as: Tumor Necrosis Factor Receptors, Receptors, TNF, receptors tnf 
Members of the tumor necrosis factor receptor (TNFR) family play a key role in regulating the immune response to infection. They are cell-surface… 
National Institutes of Health

Related topics

Related topics

30 relations
Apoptosis Regulatory ProteinsCytokine Receptor GeneCytokine Signaling ProcessIn Blood

Narrower (9)

BLyS receptorCrmE protein, Vaccinia virusRELTReceptors, Tumor Necrosis Factor, Type II

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Review
2001
Review
2001
Toll-like receptors: critical proteins linking innate and acquired immunity
Recognition of pathogens is mediated by a set of germline-encoded receptors that are referred to as pattern-recognition receptors… 
Review
2001
Review
2001
The TNF and TNF Receptor Superfamilies Integrating Mammalian Biology
Review
1999
Review
1999
Modulation of osteoclast differentiation and function by the new members of the tumor necrosis factor receptor and ligand families.
Osteoblasts/stromal cells are essentially involved in osteoclast differentiation and function through cell-to-cell contact (Fig… 
Highly Cited
1999
Highly Cited
1999
Tumor necrosis factor receptor family member RANK mediates osteoclast differentiation and activation induced by osteoprotegerin ligand.
  • H. HsuD. Lacey W. Boyle
  • Proceedings of the National Academy of Sciences…
  • 1999
  • Corpus ID: 2824245
A receptor that mediates osteoprotegerin ligand (OPGL)-induced osteoclast differentiation and activation has been identified via… 
Highly Cited
1999
Highly Cited
1999
A trial of etanercept, a recombinant tumor necrosis factor receptor:Fc fusion protein, in patients with rheumatoid arthritis receiving methotrexate.
BACKGROUND Patients treated with methotrexate for rheumatoid arthritis often improve but continue to have active disease. This… 
Highly Cited
1997
Highly Cited
1997
Treatment of rheumatoid arthritis with a recombinant human tumor necrosis factor receptor (p75)-Fc fusion protein.
BACKGROUND Tumor necrosis factor (TNF) is a proinflammatory cytokine involved in the pathogenesis of rheumatoid arthritis, and… 
Highly Cited
1997
Highly Cited
1997
Initiation of liver growth by tumor necrosis factor: deficient liver regeneration in mice lacking type I tumor necrosis factor receptor.
The mechanisms that initiate liver regeneration after resection of liver tissue are not known. To determine whether cytokines are… 
Highly Cited
1997
Highly Cited
1997
TRANCE Is a Novel Ligand of the Tumor Necrosis Factor Receptor Family That Activates c-Jun N-terminal Kinase in T Cells*
A novel member of the tumor necrosis factor (TNF) cytokine family, designated TRANCE, was cloned during a search for apoptosis… 
Highly Cited
1996
Highly Cited
1996
Treatment of septic shock with the tumor necrosis factor receptor:Fc fusion protein. The Soluble TNF Receptor Sepsis Study Group.
BACKGROUND A recombinant, soluble fusion protein that is a dimer of an extracellular portion of the human tumor necrosis factor… 
Highly Cited
1996
Highly Cited
1996
Tumor Necrosis Factor-α and Tumor Necrosis Factor Receptors in the Failing Human Heart
Background Tumor necrosis factor-α (TNF-α) is a proinflammatory cytokine that produces negative inotropic effects in the heart… 
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