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Activation signal of nuclear factor-kappa B in response to endoplasmic reticulum stress is transduced via IRE1 and tumor necrosis factor receptor-associated factor 2.
Results suggest that ER stress-induced NF-kappaB activation is also mediated by the IRE1-TRAF2 pathway, as well as JNK activation.
Human HRD1 protects against ER stress‐induced apoptosis through ER‐associated degradation1
Suppressive effects of 4‐phenylbutyrate on the aggregation of Pael receptors and endoplasmic reticulum stress
Results suggest that 4‐PBA suppresses ER stress by directly reducing the amount of misfolded protein, including Pael‐R accumulated in the ER.
A different pathway in the endoplasmic reticulum stress‐induced expression of human HRD1 and SEL1 genes
Manganese superoxide dismutase is induced by endoplasmic reticulum stress through IRE1-mediated nuclear factor (NF)-kappaB and AP-1 activation.
- M. Kaneko, Tomoko Takahashi, Yoshifumi Niinuma, Y. Nomura
- BiologyBiological & pharmaceutical bulletin
- 1 August 2004
Investigation of the expression of MnSOD in HeLa cells exposed to various agents interfering with endoplasmic reticulum (ER) functions suggests that the MnS OD expression is controlled by ER stress through IRE1-mediated NF-kappaB and AP-1 activation.
1 A different pathway in the endoplasmic reticulum stress-induced expression of human HRD 1 and SEL 1 genes
[Construction and evaluation of a cancer chemotherapy regimen database using an electronic medical chart network].
- Hidetoshi Yamada, Erika Makino, Y. Hayase
- MedicineYakugaku zasshi : Journal of the Pharmaceutical…
- 1 July 2005
Obtaining information regarding cancer chemotherapy regimens became easier with the Web-version DB, which received an excellent evaluation by all medical staff and the exceptional ability to share information among medical staff.
A Multicenter, Large-Scale Real-World Survey on Medication Adherence to Direct Oral Anticoagulants in Patients with Non-Valvular Atrial Fibrillation