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Receptors, Opioid, kappa

Known as: Receptors, kappa, kappa receptors, Receptors, kappa Opioid 
A class of opioid receptors recognized by its pharmacological profile. Kappa opioid receptors bind dynorphins with a higher affinity than endorphins… 
National Institutes of Health

Related topics

Related topics

12 relations
DynorphinsIn Bloodagonistsantagonists & inhibitors

Broader (1)

Opioid Receptor

Narrower (4)

Ro1 protein, syntheticRo2 protein, recombinantkappa(1) opioid receptorkappa(2) opioid receptor

Papers overview

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Highly Cited
2009
Highly Cited
2009
Activation of the kappa opioid receptor in the dorsal raphe nucleus mediates the aversive effects of stress and reinstates drug seeking
Although stress has profound effects on motivated behavior, the underlying mechanisms responsible are incompletely understood. In… 
Highly Cited
2001
Highly Cited
2001
Altered Responsiveness to Cocaine and Increased Immobility in the Forced Swim Test Associated with Elevated cAMP Response Element-Binding Protein Expression in Nucleus Accumbens
Drugs of abuse regulate the transcription factor cAMP response element-binding protein (CREB) in striatal regions, including the… 
Highly Cited
1994
Highly Cited
1994
cDNA Cloning of an orphan opiate receptor gene family member and its splice variant
Highly Cited
1994
Highly Cited
1994
Autoregulation of I kappa B alpha activity.
Transcription factor NF-kappa B regulates the expression of a plethora of genes. The activity of NF-kappa B proteins is regulated… 
Highly Cited
1993
Highly Cited
1993
Cloning and pharmacological characterization of a rat kappa opioid receptor.
A full-length cDNA was isolated from a rat striatal library by using low-stringency screening with two PCR fragments, one… 
Highly Cited
1988
Highly Cited
1988
Nor-binaltorphimine, a highly selective kappa-opioid antagonist in analgesic and receptor binding assays.
Previously, we reported on an opioid antagonist, nor-binaltorphimine (nor-BNI), that had high selectivity for kappa opioid… 
Highly Cited
1988
Highly Cited
1988
Enhancement of dynorphin gene expression in spinal cord following experimental inflammation: stimulus specificity, behavioral parameters and opioid receptor binding
Highly Cited
1987
Highly Cited
1987
Neuroanatomical patterns of the mu, delta, and kappa opioid receptors of rat brain as determined by quantitative in vitro autoradiography.
Highly specific radioligands and quantitative autoradiography reveal strikingly different neuroanatomical patterns for the mu… 
Highly Cited
1984
Highly Cited
1984
In vivo studies on spinal opiate receptor systems mediating antinociception. II. Pharmacological profiles suggesting a differential association of mu, delta and kappa receptors with visceral chemical…
The intrathecal administration of mu (morphine) and delta (D-Ala2-D-Leu5-enkephalin) but not kappa agonists (ethylketocyclazocine… 
Highly Cited
1982
Highly Cited
1982
Dynorphin is a specific endogenous ligand of the kappa opioid receptor.
In the guinea pig ileum myenteric plexus--longitudinal muscle preparation, dynorphin-(1--13) and the prototypical kappa agonist… 
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