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A new and sensitive method for measuring thermal nociception in cutaneous hyperalgesia
A novel behavioral model of neuropathic pain disorders produced in rats by partial sciatic nerve injury
Peripheral suppression of first pain and central summation of second pain evoked by noxious heat pulses
Characterization of basal and re-inflammation-associated long-term alteration in pain responsivity following short-lasting neonatal local inflamatory insult
Interactions between the immune and nervous systems in pain
A greater understanding of the role of the immune system in pain processing and modulation reveals potential targets for analgesic drug development and new therapeutic opportunities for managing chronic pain.
Glial–Cytokine–Neuronal Interactions Underlying the Mechanisms of Persistent Pain
Evidence is provided that demonstrates a mechanism by which glia interact with neurons, leading to activity-dependent plasticity and hyperalgesia, and the coupling of NMDA receptor phosphorylation through IL-1 receptor signaling.
Pain measurement: an overview
Supraspinal Glial–Neuronal Interactions Contribute to Descending Pain Facilitation
These studies have addressed a novel contribution of supraspinal astrocytes and associated cytokines as well as central glial–neuronal interactions to the enhancement of descending facilitation of neuropathic pain.
Activity-dependent neuronal plasticity following tissue injury and inflammation