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Receptor, Notch2

Known as: Notch2 Protein, Notch2 Receptor, Receptor, Notch2 [Chemical/Ingredient] 
A notch receptor that plays an important role in CELL DIFFERENTIATION in a variety of cell types. It is the preferentially expressed notch receptor… 
National Institutes of Health

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In BloodNOTCH2 geneagonistsantagonists & inhibitors

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NOTCH2 protein, human

Papers overview

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Highly Cited
2014
Highly Cited
2014
Pro-osteogenic topographical cues promote early activation of osteoprogenitor differentiation via enhanced TGFβ, Wnt, and Notch signaling.
OBJECTIVES Titanium implant surfaces with modified topographies have improved osteogenic properties in vivo. However, the… 
Highly Cited
2013
Highly Cited
2013
The extracellular domain of Notch2 increases its cell-surface abundance and ligand responsiveness during kidney development.
Highly Cited
2012
Highly Cited
2012
The coding genome of splenic marginal zone lymphoma: activation of NOTCH2 and other pathways regulating marginal zone development
Notch2 mutations represent the most frequent lesion in splenic marginal zone lymphoma. 
Review
2012
Review
2012
Transcriptome Profiling of the Cancer, Adjacent Non-Tumor and Distant Normal Tissues from a Colorectal Cancer Patient by Deep Sequencing
Colorectal cancer (CRC) is one of the most commonly diagnosed cancers in the world. A genome-wide screening of transcriptome… 
Highly Cited
2011
Highly Cited
2011
Gremlin 2 regulates distinct roles of BMP and Endothelin 1 signaling in dorsoventral patterning of the facial skeleton
Patterning of the upper versus lower face involves generating distinct pre-skeletal identities along the dorsoventral (DV) axes… 
Highly Cited
2011
Highly Cited
2011
Notch2/Hes-1 Pathway Plays an Important Role in Renal Ischemia and Reperfusion Injury-Associated Inflammation and Apoptosis and the γ-Secretase Inhibitor DAPT has a Nephroprotective Effect
This study aims to investigate the role of Notch pathway in the renal ischemia/reperfusion injury (IRI)-associated inflammation… 
2008
2008
Novel Meta-Analysis-Derived Type 2 Diabetes Risk Loci Do Not Determine Prediabetic Phenotypes
Background Genome-wide association (GWA) studies identified a series of novel type 2 diabetes risk loci. Most of them were… 
Highly Cited
2003
Highly Cited
2003
Notch2 Haploinsufficiency Results in Diminished B1 B Cells and a Severe Reduction in Marginal Zone B Cells 1
Recent studies have implicated a role for Notch in the generation of marginal zone (MZ) B cells. To further investigate the role… 
2003
2003
Notch2 protein distribution in human teeth under normal and pathological conditions.
Highly Cited
1998
Highly Cited
1998
Roles of the ankyrin repeats and C-terminal region of the mouse notch1 intracellular region.
The Notch intracellular region (RAMIC) interacts with a DNA binding protein RBP-J to activate transcription of genes that inhibit… 
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