T. Schilling

Publications147
h-index50
Citations17,410
Highly Influential Citations1,599
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Stages of embryonic development of the zebrafish
We describe a series of stages for development of the embryo of the zebrafish, Danio (Brachydanio) rerio. We define seven broad periods of embryogenesis—the zygote, cleavage, blastula, gastrula,… Expand
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The zebrafish neckless mutation reveals a requirement for raldh2 in mesodermal signals that pattern the hindbrain.
We describe a new zebrafish mutation, neckless, and present evidence that it inactivates retinaldehyde dehydrogenase type 2, an enzyme involved in retinoic acid biosynthesis. neckless embryos are… Expand
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Structure of the zebrafish snail1 gene and its expression in wild-type, spadetail and no tail mutant embryos.
Mesoderm formation is critical for the establishment of the animal body plan and in Drosophila requires the snail gene. This report concerns the cloning and expression pattern of the structurally… Expand
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Origin and organization of the zebrafish fate map.
We have analyzed lineages of cells labeled by intracellular injection of tracer dye during early zebrafish development to learn when cells become allocated to particular fates during development, and… Expand
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Hedgehog signaling is required for cranial neural crest morphogenesis and chondrogenesis at the midline in the zebrafish skull
Neural crest cells that form the vertebrate head skeleton migrate and interact with surrounding tissues to shape the skull, and defects in these processes underlie many human craniofacial syndromes.… Expand
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sucker encodes a zebrafish Endothelin-1 required for ventral pharyngeal arch development.
Mutation of sucker (suc) disrupts development of the lower jaw and other ventral cartilages in pharyngeal segments of the zebrafish head. Our sequencing, cosegregation and rescue results indicate… Expand
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lockjaw encodes a zebrafish tfap2a required for early neural crest development
The neural crest is a uniquely vertebrate cell type that gives rise to much of the craniofacial skeleton, pigment cells and peripheral nervous system, yet its specification and diversification during… Expand
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Segment and cell type lineage restrictions during pharyngeal arch development in the zebrafish embryo.
In zebrafish, the segmental series of pharyngeal arches is formed predominantly by two migratory cell types, neural crest and paraxial mesoderm, which arise in the early embryo. Neural crest cells… Expand
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Requirement for endoderm and FGF3 in ventral head skeleton formation.
The vertebrate head skeleton is derived in part from neural crest cells, which physically interact with head ectoderm, mesoderm and endoderm to shape the pharyngeal arches. The cellular and molecular… Expand
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Jaw and branchial arch mutants in zebrafish I: branchial arches.
Jaws and branchial arches together are a basic, segmented feature of the vertebrate head. Seven arches develop in the zebrafish embryo (Danio rerio), derived largely from neural crest cells that form… Expand
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