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NOTCH2 gene

Known as: notch 2, Notch 2 Gene, NOTCH, DROSOPHILA, HOMOLOG OF, 2 
This gene plays a role in cell-cell signaling.
National Institutes of Health

Related topics

Related topics

9 relations
Cell Fate ControlLigand BindingNOTCH2 protein, humanNegative Regulation of Apoptosis

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NOTCH2 wt Allele

Papers overview

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2019
2019
Novel mutations in NOTCH2 gene in infants with neonatal cholestasis
One cause of neonatal cholestasis (NC) is paucity of intrahepatic bile ducts which can be associated with Alagille syndrome or… 
2017
2017
Dysregulation of miR-181c expression influences recurrence of endometrial endometrioid adenocarcinoma by modulating NOTCH2 expression: An NRG Oncology/Gynecologic Oncology Group study.
2017
2017
Comparative analysis of Notch1 and Notch2 binding sites in the genome of BxPC3 pancreatic cancer cells
Notch signaling plays a key role in the development of pancreatic cancer. Among the four identified Notch receptors, Notch1 and… 
2016
2016
Genes Associated with Increased Fasting Glucose in Patients with Schizophrenia Spectrum Disorders
Background: Metabolic risk factors represent a major cause of increased coronary heart disease morbidity and mortality among… 
2013
2013
The Different Role of Notch1 and Notch2 in Astrocytic Gliomas
It is well known that Notch signaling plays either oncogenic or tumor suppressive role in a variety of tumors, depending on the… 
2013
2013
NOTCH2 expression is decreased in epithelial ovarian cancer and is related to the tumor histological subtype.
BACKGROUND Notch family members function as both oncogenes and tumor suppressors. NOTCH2 is down-regulated in colon cancer, and… 
Highly Cited
2012
Highly Cited
2012
Notch2‐induced COX‐2 expression enhancing gastric cancer progression
Gastric carcinoma is one of the most common and mortal types of malignancy worldwide. To date, the mechanisms controlling its… 
2011
2011
Association of indices of liver and adipocyte insulin resistance with 19 confirmed susceptibility loci for type 2 diabetes in 6,733 non-diabetic Finnish men
Aims/hypothesisOf the confirmed type 2 diabetes susceptibility loci only a few are known to affect insulin sensitivity. We… 
2009
2009
Notch2 Expression Is Decreased in Colorectal Cancer and Related to Tumor Differentiation Status
BackgroundThe significance of Notch2 expression in colorectal cancer (CRC) has not been clearly investigated. We investigated the… 
Highly Cited
1997
Highly Cited
1997
Neoplastic transformation by truncated alleles of human NOTCH1/TAN1 and NOTCH2
The Notch genes of Drosophila melanogaster and vertebrates encode transmembrane receptors that help determine cell fate during… 
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