NOTCH2 protein, human

Known as: Notch homolog 2 (Drosophila) protein, human, notch-2 protein, human, Notch 2 
Neurogenic locus notch homolog protein 2 (2471 aa, ~265 kDa) is encoded by the human NOTCH2 gene. This protein plays a role in intercellular… (More)
National Institutes of Health

Topic mentions per year

Topic mentions per year

1946-2017
05019462016

Papers overview

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Highly Cited
2013
Highly Cited
2013
Defense against attaching-and-effacing bacteria requires the sequential generation of interleukin 23 (IL-23) and IL-22 to induce… (More)
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Highly Cited
2011
Highly Cited
2011
Dendritic cells (DCs) in tissues and lymphoid organs comprise distinct functional subsets that differentiate in situ from… (More)
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Highly Cited
2007
Highly Cited
2007
The Notch pathway regulates cell fate determination in numerous developmental processes. Here we report that Notch2 acts non… (More)
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Highly Cited
2003
Highly Cited
2003
The Notch genes play a key role in cellular differentiation. The significance of Notch1 during thymocyte development is well… (More)
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Highly Cited
2001
Highly Cited
2001
In the developing cerebellar cortex, granule neuron precursors (GNPs) proliferate and commence differentiation in a superficial… (More)
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Highly Cited
2001
Highly Cited
2001
The role of Notch signaling in growth/differentiation control of mammalian epithelial cells is still poorly defined. We show that… (More)
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Highly Cited
2001
Highly Cited
2001
The Notch gene family encodes large transmembrane receptors that are components of an evolutionarily conserved intercellular… (More)
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Highly Cited
2000
Highly Cited
2000
Proteins encoded by the fringe family of genes are required to modulate Notch signalling in a wide range of developmental… (More)
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Highly Cited
1999
Highly Cited
1999
Notch family genes encode transmembrane proteins involved in cell-fate determination. Using gene targeting procedures, we… (More)
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Highly Cited
1992
Highly Cited
1992
Notch is a cell surface receptor that mediates a wide variety of cellular interactions that specify cell fate during Drosophila… (More)
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