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  • Jacob S. Lee, Marina Cella, +8 authors Marco Colonna
  • Biology, Medicine
  • Nature Immunology
  • 2011 (First Publication: 1 February 2012)
  • Innate lymphoid cells (ILCs) of the ILC22 type protect the intestinal mucosa from infection by secreting interleukin 22 (IL-22). ILC22 cells include NKp46+ and lymphoid tissue–inducer (LTi)-likeContinue Reading
  • Jeff S. Mumm, Raphael Kopan
  • Biology, Medicine
  • Developmental biology
  • 2000 (First Publication: 1 December 2000)
  • Development makes reiterative use of a surprisingly small set of essential molecular signals: the Wingless (Wg/ Wnt), Hedgehog (Hh), Transforming Growth Factor-b (TGFb), Receptor TyrosineContinue Reading
  • Amy E Kiernan, Ralf Cordes, Raphael Kopan, Achim Gossler, Thomas Gridley
  • Biology, Medicine
  • Development
  • 2005 (First Publication: 1 October 2005)
  • The mammalian auditory sensory epithelium, the organ of Corti, contains sensory hair cells and nonsensory supporting cells arranged in a highly patterned mosaic. Notch-mediated lateral inhibition isContinue Reading