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Cell Fate Control

Known as: Cell Fate Regulation 
Cell Fate Control involves intercellular, cellular, and intracellular processes that regulate the generally irreversible commitment of a multipotent… Expand
National Institutes of Health

Related topics

Related topics

50 relations
Gene ExpressionIntercellular Communication ProcessJAG2 protein, humanLEFTB protein, human
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Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Review
2018
Review
2018
Signaling in the stem cell niche: regulating cell fate, function and plasticity
ABSTRACT Stem cells have the ability to self-renew and differentiate along multiple lineages, driving tissue homeostasis and… Expand
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Review
2016
Review
2016
Pioneer transcription factors, chromatin dynamics, and cell fate control.
  • K. Zaret, S. Mango
  • Current opinion in genetics & development
  • 2016
    • Corpus ID: 45121219
Among the diverse transcription factors that are necessary to elicit changes in cell fate, both in embryonic development and in… Expand
Review
2015
Review
2015
RB1 dual role in proliferation and apoptosis: Cell fate control and implications for cancer therapy
Inactivation of the retinoblastoma (RB1) tumor suppressor is one of the most frequent and early recognized molecular hallmarks of… Expand
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Highly Cited
2012
Highly Cited
2012
Rosmarinic acid and baicalin epigenetically derepress peroxisomal proliferator‐activated receptor γ in hepatic stellate cells for their antifibrotic effect
Hepatic stellate cells (HSCs) undergo myofibroblastic transdifferentiation (activation) to participate in liver fibrosis and… Expand
Highly Cited
2010
Highly Cited
2010
The histone demethylase UTX enables RB-dependent cell fate control.
Trimethylation of histone H3 on Lys 27 (H3K27me3) is key for cell fate regulation. The H3K27me3 demethylase UTX functions in… Expand
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Highly Cited
2009
Highly Cited
2009
SIRT1 Suppresses Activator Protein-1 Transcriptional Activity and Cyclooxygenase-2 Expression in Macrophages*
SIRT1 (Sirtuin type 1), a mammalian orthologue of yeast SIR2 (silent information regulator 2), has been shown to mediate a… Expand
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Highly Cited
2008
Highly Cited
2008
Establishment of endoderm progenitors by SOX transcription factor expression in human embryonic stem cells.
In this study, we explore endoderm cell fate regulation through the expression of lineage-determining transcription factors. We… Expand
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Highly Cited
2007
Highly Cited
2007
Electrical Stimulation Modulates Fate Determination of Differentiating Embryonic Stem Cells
A clear understanding of cell fate regulation during differentiation is key in successfully using stem cells for therapeutic… Expand
Highly Cited
2006
Highly Cited
2006
Dissecting self-renewal in stem cells with RNA interference
We present an integrated approach to identify genetic mechanisms that control self-renewal in mouse embryonic stem cells. We use… Expand
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Review
1999
Review
1999
Notch signaling: cell fate control and signal integration in development.
Notch signaling defines an evolutionarily ancient cell interaction mechanism, which plays a fundamental role in metazoan… Expand
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