Cell Fate Control

Known as: Cell Fate Regulation 
Cell Fate Control involves intercellular, cellular, and intracellular processes that regulate the generally irreversible commitment of a multipotent… (More)
National Institutes of Health

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Gene ExpressionIntercellular Communication ProcessJAG2 protein, humanLEFTB protein, human
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Papers overview

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Review
2016
Review
2016
Pioneer transcription factors, chromatin dynamics, and cell fate control.
Among the diverse transcription factors that are necessary to elicit changes in cell fate, both in embryonic development and in… (More)
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Review
2015
Review
2015
Computational modelling of embryonic stem-cell fate control.
The maintenance of pluripotency in embryonic stem cells (ESCs), its loss during lineage specification or its re-induction to… (More)
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Review
2015
Review
2015
Transcriptional control of stem cell fate by E2Fs and pocket proteins
E2F transcription factors and their regulatory partners, the pocket proteins (PPs), have emerged as essential regulators of stem… (More)
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2014
2014
The importance of three-dimensional scaffold structure on stemness maintenance of mouse embryonic stem cells.
Revealing the mechanisms of cell fate regulation is important for scientific research and stem cell-based therapy. The… (More)
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2011
2011
Synthetic human cell fate regulation by protein-driven RNA switches
Understanding how to control cell fate is crucial in biology, medical science and engineering. In this study, we introduce a… (More)
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Highly Cited
2010
Highly Cited
2010
The histone demethylase UTX enables RB-dependent cell fate control.
Trimethylation of histone H3 on Lys 27 (H3K27me3) is key for cell fate regulation. The H3K27me3 demethylase UTX functions in… (More)
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Highly Cited
2008
Highly Cited
2008
Establishment of endoderm progenitors by SOX transcription factor expression in human embryonic stem cells.
In this study, we explore endoderm cell fate regulation through the expression of lineage-determining transcription factors. We… (More)
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Highly Cited
2006
Highly Cited
2006
Dissecting self-renewal in stem cells with RNA interference
We present an integrated approach to identify genetic mechanisms that control self-renewal in mouse embryonic stem cells. We use… (More)
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Highly Cited
2006
Highly Cited
2006
Electrical stimulation modulates fate determination of differentiating embryonic stem cells.
A clear understanding of cell fate regulation during differentiation is key in successfully using stem cells for therapeutic… (More)
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Review
1999
Review
1999
Notch signaling: cell fate control and signal integration in development.
Notch signaling defines an evolutionarily ancient cell interaction mechanism, which plays a fundamental role in metazoan… (More)
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