Skip to search formSkip to main content
You are currently offline. Some features of the site may not work correctly.

JAG2 protein, human

Known as: Protein Jagged-2, Jagged 2, Jagged2 
Protein jagged-2 (1238 aa, ~133 kDa) is encoded by the human JAG2 gene. This protein plays a role in cellular differentiation.
National Institutes of Health

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2009
Highly Cited
2009
Notch signaling is involved in tumorigenesis, but its role in B-chronic lymphocytic leukemia (B-CLL) pathogenesis is not… Expand
  • table 1
  • figure 1
  • figure 2
  • figure 3
  • figure 4
Is this relevant?
Highly Cited
2005
Highly Cited
2005
BACKGROUND & AIMS The mammalian pancreas has a strong regenerative potential, but the origin of organ restoration is not clear… Expand
Is this relevant?
Highly Cited
2005
Highly Cited
2005
Although Notch receptor expression on malignant B cells is widespread, the effect of Notch signaling in these cells is poorly… Expand
  • table 1
  • figure 1
  • figure 3
  • figure 4
  • figure 5
Is this relevant?
Highly Cited
2005
Highly Cited
2005
γ-Secretase facilitates the regulated intramembrane proteolysis of select type I membrane proteins that play diverse… Expand
  • figure 2
  • figure 1
  • figure 3
  • figure 4
  • figure 5
Is this relevant?
Highly Cited
2001
Highly Cited
2001
Mice with targeted mutations in genes required for Notch signal transduction die during embryogenesis, displaying overt signs of… Expand
  • figure 1
  • figure 2
Is this relevant?
Highly Cited
2001
Highly Cited
2001
The Jagged/Notch signaling pathways control cell fate determination and differentiation, and their dysfunction is associated with… Expand
Is this relevant?
Highly Cited
1999
Highly Cited
1999
Hematopoiesis is a balance between proliferation and differentiation that may be modulated by environmental signals. Notch… Expand
  • figure 1
  • figure 2
  • table 1
  • figure 3
  • figure 4
Is this relevant?
Highly Cited
1998
Highly Cited
1998
ABSTRACT The Notch receptor is involved in many cell fate determination events in vertebrates and invertebrates. It has been… Expand
  • figure 1
  • figure 2
  • figure 3
  • figure 5
  • figure 4
Is this relevant?
Highly Cited
1998
Highly Cited
1998
The Notch signaling pathway is a conserved intercellular signaling mechanism that is essential for proper embryonic development… Expand
Is this relevant?
Highly Cited
1997
Highly Cited
1997
Signaling through Notch receptors has been implicated in the control of cellular differentiation in animals ranging from… Expand
  • figure 1
  • figure 2
  • figure 3
  • figure 6
  • figure 5
Is this relevant?