JAG2 protein, human

Known as: Protein Jagged-2, Jagged 2, Jagged2 
Protein jagged-2 (1238 aa, ~133 kDa) is encoded by the human JAG2 gene. This protein plays a role in cellular differentiation.
National Institutes of Health

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Highly Cited
2007
Highly Cited
2007
PURPOSE Retinoblastoma (RB) is the most common intraocular tumor of early childhood. The early onset of RB, coupled with our… (More)
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Highly Cited
2005
Highly Cited
2005
Gamma-secretase facilitates the regulated intramembrane proteolysis of select type I membrane proteins that play diverse… (More)
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Highly Cited
2005
Highly Cited
2005
Although Notch receptor expression on malignant B cells is widespread, the effect of Notch signaling in these cells is poorly… (More)
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Highly Cited
2004
Highly Cited
2004
Hepatic regeneration from toxic or surgical injury to the adult mammalian liver, endorses different cellular responses within the… (More)
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Highly Cited
2003
Highly Cited
2003
FGF10 plays an important role in the morphogenesis of several tissues by control of mesenchymal-to-epithelial signaling. In the… (More)
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Highly Cited
2002
Highly Cited
2002
The molecular mechanisms by which Notch receptors induce diverse biological responses are not fully understood. We recently… (More)
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Highly Cited
2000
Highly Cited
2000
The sensory epithelium within the mammalian cochlea (the organ of Corti) is a strictly ordered cellular array consisting of… (More)
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Highly Cited
2000
Highly Cited
2000
Delta1, Jagged1, and Jagged2, commonly designated Delta/Serrate/LAG-2 (DSL) proteins, are known to be ligands for Notch1. However… (More)
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Highly Cited
1998
Highly Cited
1998
The Notch receptor is involved in many cell fate determination events in vertebrates and invertebrates. It has been shown in… (More)
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Highly Cited
1998
Highly Cited
1998
The Notch signaling pathway is a conserved intercellular signaling mechanism that is essential for proper embryonic development… (More)
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