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Negative Regulation of Apoptosis

Known as: Inhibition of Apoptosis, negative regulation of apoptotic process, downregulation of apoptosis 
Any process that stops, prevents, or reduces the frequency, rate or extent of cell death by apoptotic process. [GOC:jl, GOC:mtg_apoptosis]
National Institutes of Health

Related topics

Related topics

50 relations
ANGPTL4 geneANGPTL4 wt AlleleAstrocytic Phosphoprotein PEA-15BAG Family Molecular Chaperone Regulator 3, human

Broader (1)

biological control

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Review
2008
Review
2008
Survivin: Key Regulator of Mitosis and Apoptosis and Novel Target for Cancer Therapeutics
Survivin, a member of the family of inhibitor of apoptosis proteins, functions as a key regulator of mitosis and programmed cell… 
Highly Cited
2006
Highly Cited
2006
Analysis of gene expression and chemoresistance of CD133+ cancer stem cells in glioblastoma
BackgroundRecently, a small population of cancer stem cells in adult and pediatric brain tumors has been identified. Some… 
Review
2002
Review
2002
Mitochondrial reactive oxygen species in cell death signaling.
Highly Cited
1998
Highly Cited
1998
Control of apoptosis and mitotic spindle checkpoint by survivin
Progression of the cell cycle and control of apoptosis (programmed cell death) are thought to be intimately linked processes… 
Highly Cited
1998
Highly Cited
1998
Stat3 Activation Is Required for Cellular Transformation by v-src
ABSTRACT Stat3 activation has been associated with cytokine-induced proliferation, anti-apoptosis, and transformation… 
Highly Cited
1998
Highly Cited
1998
Attenuation of Delayed Neuronal Death after Mild Focal Ischemia in Mice by Inhibition of the Caspase Family
Inhibitors of apoptosis and of excitotoxic cell death reduce brain damage after transient and permanent middle cerebral artery… 
Highly Cited
1997
Highly Cited
1997
A novel anti-apoptosis gene, survivin, expressed in cancer and lymphoma
Inhibitors of programmed cell death (apoptosis) aberrantly prolonging cell viability may contribute to cancer1 by facilitating… 
Highly Cited
1996
Highly Cited
1996
Two signals are necessary for cell proliferation induced by a cytokine receptor gp130: involvement of STAT3 in anti-apoptosis.
Highly Cited
1994
Highly Cited
1994
BH1 and BH2 domains of Bcl-2 are required for inhibition of apoptosis and heterodimerization with Bax
BCL-2 was isolated from the t(14;18) chromosomal breakpoint in follicular B-cell lymphoma1–3. Bcl-2 has the unique oncogenic role… 
Highly Cited
1994
Highly Cited
1994
Control of programmed cell death by the baculovirus genes p35 and iap
The SF-21 insect cell line undergoes rapid and widespread apoptosis when treated with actinomycin D or when infected with a… 
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