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Negative Regulation of Apoptosis

Known as: Inhibition of Apoptosis, negative regulation of apoptotic process, downregulation of apoptosis 
Any process that stops, prevents, or reduces the frequency, rate or extent of cell death by apoptotic process. [GOC:jl, GOC:mtg_apoptosis]
National Institutes of Health

Related topics

Related topics

50 relations
ANGPTL4 geneANGPTL4 wt AlleleAstrocytic Phosphoprotein PEA-15BAG Family Molecular Chaperone Regulator 3, human
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Broader (1)

biological control

Papers overview

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Review
2019
Review
2019
Glycosylation in health and disease
The glycome describes the complete repertoire of glycoconjugates composed of carbohydrate chains, or glycans, that are covalently… Expand
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Review
2019
Review
2019
STAT3 as a potential therapeutic target in triple negative breast cancer: a systematic review
Triple negative breast cancer (TNBC), which is typically lack of expression of estrogen receptor (ER), progesterone receptor (PR… Expand
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Highly Cited
2006
Highly Cited
2006
Analysis of gene expression and chemoresistance of CD133+ cancer stem cells in glioblastoma
BackgroundRecently, a small population of cancer stem cells in adult and pediatric brain tumors has been identified. Some… Expand
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Review
2000
Review
2000
Mitochondrion as a novel target of anticancer chemotherapy.
Mitochondrial membrane permeabilization is a critical event in the process leading to physiologic or chemotherapy-induced… Expand
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Highly Cited
1998
Highly Cited
1998
Control of apoptosis and mitotic spindle checkpoint by survivin
Progression of the cell cycle and control of apoptosis (programmed cell death) are thought to be intimately linked processes… Expand
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Highly Cited
1998
Highly Cited
1998
Stat3 Activation Is Required for Cellular Transformation by v-src
ABSTRACT Stat3 activation has been associated with cytokine-induced proliferation, anti-apoptosis, and transformation… Expand
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Highly Cited
1998
Highly Cited
1998
Attenuation of Delayed Neuronal Death after Mild Focal Ischemia in Mice by Inhibition of the Caspase Family
Inhibitors of apoptosis and of excitotoxic cell death reduce brain damage after transient and permanent middle cerebral artery… Expand
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Highly Cited
1997
Highly Cited
1997
A novel anti-apoptosis gene, survivin, expressed in cancer and lymphoma
Inhibitors of programmed cell death (apoptosis) aberrantly prolonging cell viability may contribute to cancer1 by facilitating… Expand
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Highly Cited
1996
Highly Cited
1996
Two signals are necessary for cell proliferation induced by a cytokine receptor gp130: involvement of STAT3 in anti-apoptosis.
gp130 is a common signal transducer for the interleukin-6-related cytokines. To delineate the gp130-mediated growth signal, we… Expand
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Highly Cited
1994
Highly Cited
1994
BH1 and BH2 domains of Bcl-2 are required for inhibition of apoptosis and heterodimerization with Bax
BCL-2 was isolated from the t(14;18) chromosomal breakpoint in follicular B-cell lymphoma1–3. Bcl-2 has the unique oncogenic role… Expand
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