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Negative Regulation of Apoptosis

Known as: Inhibition of Apoptosis, negative regulation of apoptotic process, downregulation of apoptosis 
Any process that stops, prevents, or reduces the frequency, rate or extent of cell death by apoptotic process. [GOC:jl, GOC:mtg_apoptosis]
National Institutes of Health

Related topics

Related topics

50 relations
ANGPTL4 geneANGPTL4 wt AlleleAstrocytic Phosphoprotein PEA-15BAG Family Molecular Chaperone Regulator 3, human

Broader (1)

biological control

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2016
Highly Cited
2016
Hsa-miR-329 exerts tumor suppressor function through down-regulation of MET in non-small cell lung cancer
MicroRNAs (miRNAs) act as key regulators of multiple cancers. Hsa-miR-329 (miR-329) functions as a tumor suppressor in some… 
Highly Cited
2014
Highly Cited
2014
A Caspase-Dependent Pathway Is Involved in Wnt/β-Catenin Signaling Promoted Apoptosis in Bacillus Calmette-Guerin Infected RAW264.7 Macrophages
Apoptosis of alveolar macrophages following Mycobacterium tuberculosis infection have been demonstrated to play a central role in… 
Highly Cited
2010
Highly Cited
2010
RNAase-III enzyme Dicer maintains signaling pathways for differentiation and survival in mouse cortical neural stem cells
An important function of the RNAase-III enzyme Dicer is to process microRNA precursors into ~22-nucleotide non-coding small RNAs… 
Highly Cited
2005
Highly Cited
2005
Combination of cyclooxygenase-2 inhibitors and oxaliplatin increases the growth inhibition and death in human colon cancer cells.
Highly Cited
2003
Highly Cited
2003
Survivin expression in the stomach: implications for mucosal integrity and protection.
Highly Cited
2001
Highly Cited
2001
Expression of p53 and human herpesvirus‐8 (HHV‐8)–encoded latency‐associated nuclear antigen with inhibition of apoptosis in HHV‐8–associated malignancies
Kaposi sarcoma (KS) and primary effusion lymphoma (PEL) cells express human herpesvirus‐8 (HHV‐8)–encoded latency‐associated… 
Highly Cited
2001
Highly Cited
2001
Molluscum contagiosum virus inhibitors of apoptosis: The MC159 v-FLIP protein blocks Fas-induced activation of procaspases and degradation of the related MC160 protein.
Molluscum contagiosum virus contains two open reading frames, MC159 and MC160, that encode proteins with death effector domains… 
Highly Cited
2000
Highly Cited
2000
Inhibition of in vitro spontaneous apoptosis by IL-7 correlates with bcl-2 up-regulation, cortical/mature immunophenotype, and better early cytoreduction of childhood T-cell acute lymphoblastic…
In normal T-cell development, IL-7 plays a nonredundant role as an antiapoptic factor by regulating Bcl-2 expression in pro-T… 
Highly Cited
1997
Highly Cited
1997
The ability of BHRF1 to inhibit apoptosis is dependent on stimulus and cell type
The development of resistance to host defense mechanisms such as tumor necrosis factor (TNF)- and Fas-mediated apoptosis of… 
Highly Cited
1996
Highly Cited
1996
Functional dissection of the human Bc12 protein: sequence requirements for inhibition of apoptosis
Overexpression of the cytoplasmic oncoprotein Bc12 blocks programmed cell death (apoptosis) in many cellular systems. To map the… 
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