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RGS Domain

Known as: RGS-Signaling Domain, Regulators of G Protein Signaling Domain 
Typically 120 amino acids long, the RGS (Regulator of G protein Signaling) Domain is found in over 20 human proteins, bind activated G-alpha subunits… 
National Institutes of Health

Related topics

Related topics

18 relations
A-Kinase Anchor Protein 10, MitochondrialAXIN2 protein, humanBeta-Adrenergic Receptor Kinase 1Beta-Adrenergic Receptor Kinase 2

Papers overview

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2016
2016
Potent inhibition of angiotensin AT1 receptor signaling by RGS8: importance of the C-terminal third exon part of its RGS domain
Abstract R4/B subfamily RGS (regulator of G protein signaling) proteins play roles in regulation of many GPCR-mediated responses… 
2013
2013
Crystallization and preliminary X-ray diffraction studies of Drosophila melanogaster Gαo-subunit of heterotrimeric G protein in complex with the RGS domain of CG5036.
Regulator of G-protein signalling (RGS) proteins negatively regulate heterotrimeric G-protein signalling through their conserved… 
Review
2012
Review
2012
RGS17 (regulator of G-protein signaling 17)
Review on RGS17 (regulator of G-protein signaling 17), with data on DNA, on the protein encoded, and where the gene is implicated… 
2007
2007
Solution structure of the RGS domain of human RGS14
2005
2005
Novel activity of RGS14 on Goalpha and Gialpha nucleotide binding and hydrolysis distinct from its RGS domain and GDI activity.
The bifunctional protein RGS14 is both a GTPase activating protein (GAP) for Gialpha and Goalphaand a guanine nucleotide… 
2003
2003
Relative contributions of RGS4 and RGS domain of GRK2 to inhibition of PLC-β activity by PKA: Direct evidence from site directed mutagenesis of RGS4 and GRK2
Highly Cited
2002
Highly Cited
2002
Interaction of 14-3-3 Protein with Regulator of G Protein Signaling 7 Is Dynamically Regulated by Tumor Necrosis Factor-α*
Regulators of G protein signaling (RGS) constitute a family of proteins with a conserved RGS domain of ∼120 amino acids that… 
2002
2002
Unique Isoform of Gα-interacting Protein (RGS-GAIP) Selectively Discriminates between Two Go-mediated Pathways That Inhibit Ca2+ Channels*
Regulators of G-proteinsignaling (RGS) proteins constitute a large family of GTPase-activating proteins for heterotrimeric G… 
2002
2002
RGS domain in the amino terminus of G protein-coupled receptor kinase 2 inhibits Gq-mediated signaling
2001
2001
Differential capacities of the RGS1, RGS16 and RGS-GAIP regulators of G protein signaling to enhance alpha2A-adrenoreceptor agonist-stimulated GTPase activity of G(o1)alpha.
Recombinant RGS1, RGS16 and RGS-GAIP, but not RGS2, were able to substantially further stimulate the maximal GTPase activity of G… 
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