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Beta-Adrenergic Receptor Kinase 2

Known as: Beta-ARK-2, EC 2.7.1.126, Beta Adrenergic Receptor Kinase 2 
A ubiquitously expressed G-protein-coupled receptor kinase subtype that has specificity for the agonist-occupied form of BETA-ADRENERGIC RECEPTORS… Expand
National Institutes of Health

Papers overview

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Highly Cited
2011
Highly Cited
2011
Background: Antimicrobial peptide LL-37 activates leukocytes, mast cells, and endothelial cells. Results: LL-37 causes chemotaxis… Expand
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Highly Cited
2010
Highly Cited
2010
Pasireotide (SOM230) is currently under clinical evaluation as a successor compound to octreotide for the treatment of acromegaly… Expand
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Highly Cited
2009
Highly Cited
2009
CCL19 and CCL21 are endogenous agonists for the seven-transmembrane receptor CCR7. They are equally active in promoting G protein… Expand
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Highly Cited
2008
Highly Cited
2008
We have used RNA interference previously to demonstrate that G protein-coupled receptor kinase 2 (GRK2) regulates endogenously… Expand
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Highly Cited
2006
Highly Cited
2006
In this study we investigated the mechanisms responsible for MAP kinase ERK1/2 activation following agonist activation of… Expand
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Highly Cited
1999
Highly Cited
1999
G protein-coupled receptor kinases (GRKs) are well characterized regulators of G protein-coupled receptors, whereas regulators of… Expand
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Highly Cited
1999
Highly Cited
1999
Desensitization of cannabinoid receptor signaling by a G-protein coupled receptor kinase (GRK) was examined using theXenopus… Expand
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Highly Cited
1996
Highly Cited
1996
The role of G protein-coupled receptor kinases (GRKs) in the regulation of dopamine D1A receptor responsiveness is poorly… Expand
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Review
1995
Review
1995
G protein-coupled receptor kinases (GRKs) are a family of serine/threonine protein kinases that specifically recognize agonist… Expand
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Highly Cited
1991
Highly Cited
1991
The beta-adrenergic receptor kinase (beta ARK) specifically phosphorylates the agonist-occupied form of the beta-adrenergic and… Expand
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