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Beta-Adrenergic Receptor Kinase 1

Known as: Beta-ARK-1, EC 2.7.1.126, beta Adrenergic Receptor Kinase 1 
A ubiquitously expressed G-protein-coupled receptor kinase subtype that has specificity for the agonist-occupied form of BETA-ADRENERGIC RECEPTORS… 
National Institutes of Health

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27 relations
ADRBK1 geneADRBK1 wt AlleleBeta-Adrenergic Receptor Kinase 2Cytoplasm

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muscarinic receptor kinase

Papers overview

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2018
2018
G protein g (Gg) subtype dependent targeting of GRK2 to M3 receptor by Gbg
Interactions of cytosolic G protein coupled receptor kinase 2 (GRK2) with activated G protein coupled receptors (GPCRs) induce… 
2017
2017
Alpha-MSH induces vasodilatation and exerts cardioprotection via the heme-oxygenase pathway in rat hearts
Alpha-melanocyte-stimulating hormone ( α-MSH) is a protein with known capacity for protection against cardiovascular ischemia… 
2016
2016
Molecular basis for the potential role of GRK2 in pathological disorders.
G protein-coupled receptor kinase 2(GRK2) is a ubiquitous member of the family of GRKs that are serine/threonine kinases… 
2014
2014
G protein-coupled receptor kinase 2 moderates recruitment of THP-1 cells to the endothelium by limiting histamine-invoked Weibel-Palade body exocytosis.
BACKGROUND G protein-coupled receptors (GP-CRs) are a major family of signaling molecules, central to the regulation of… 
2013
2013
Determines the Outcome to Cardiac Ischemic Injury Convergence of G Protein-Coupled Receptor and S-Nitrosylation Signaling `
2012
2012
Regulation of the Dopamine D1-D2 Receptor Heterooligomer
Dopamine receptors are members of the G protein-coupled receptor superfamily and play important roles in neuronal transmission. A… 
2011
2011
Abstract P339: The Mechanistic Relationship Between GRK2 and eNOS During Cardiac Ischemia/Reperfusion Injury
Background: Previous studies have shown that both cardiac-specific GRK2 transgenic (TG) (αMHC-GRK2) mice and eNOS knockout (KO… 
2010
2010
ROLES OF P2Y2 PURINERGIC RECEPTOR AND LIPID RAFTS IN BONE CELL MECHANOTRANSDUCTION
As said in the first chapter, our long term goal is to discover the mechanisms behind bone cell mechanotransduction. We… 
2006
2006
Regulation of G-protein coupled receptor kinases GRK2 and GRK5 in heart transplantation candidates supported by ventricular assist devices
2004
2004
Structural basis for the regulation of GRK2 by G[beta][gamma]