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Beta-Adrenergic Receptor Kinase 1

Known as: Beta-ARK-1, EC 2.7.1.126, beta Adrenergic Receptor Kinase 1 
A ubiquitously expressed G-protein-coupled receptor kinase subtype that has specificity for the agonist-occupied form of BETA-ADRENERGIC RECEPTORS… Expand
National Institutes of Health

Papers overview

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Highly Cited
2011
Highly Cited
2011
Different patterns of GPCR phosphorylation produce distinct conformations of β-arrestin and specific downstream responses… Expand
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Highly Cited
2009
Highly Cited
2009
AIMS Insulin (Ins) resistance (IRES) associates to increased cardiovascular risk as observed in metabolic syndrome. Chronic… Expand
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Highly Cited
2005
Highly Cited
2005
Signaling through beta-arrestins is a recently appreciated mechanism used by seven-transmembrane receptors. Because G protein… Expand
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Highly Cited
2003
Highly Cited
2003
Feedback inhibition is a fundamental principle in signal transduction allowing rapid adaptation to different stimuli. In… Expand
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Highly Cited
1999
Highly Cited
1999
G protein-coupled receptor kinases (GRKs) are well characterized regulators of G protein-coupled receptors, whereas regulators of… Expand
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Highly Cited
1999
Highly Cited
1999
The G protein-coupled chemokine receptor CXCR4 serves as the primary coreceptor for entry of T-cell tropic human immunodeficiency… Expand
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Highly Cited
1999
Highly Cited
1999
The binding of CC chemokines to CC chemokine receptor 5 (CCR5) triggers cellular responses that, generally, are only transient in… Expand
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Highly Cited
1996
Highly Cited
1996
Rapid desensitization of G protein-coupled receptors is mediated, at least in part, by their phosphorylation by the G protein… Expand
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Highly Cited
1995
Highly Cited
1995
Receptors that couple to the heterotrimeric G proteins, Gi or Gq, can stimulate phosphoinositide (PI) hydrolysis and mitogen… Expand
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Highly Cited
1995
Highly Cited
1995
Recoverin (Rv) is a myristoylated Ca-binding protein present primarily in bovine photoreceptors. It represents a newly identified… Expand
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