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Beta-Adrenergic Receptor Kinase 1

Known as: Beta-ARK-1, EC 2.7.1.126, beta Adrenergic Receptor Kinase 1 
A ubiquitously expressed G-protein-coupled receptor kinase subtype that has specificity for the agonist-occupied form of BETA-ADRENERGIC RECEPTORS… 
National Institutes of Health

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Related topics

27 relations
ADRBK1 geneADRBK1 wt AlleleBeta-Adrenergic Receptor Kinase 2Cytoplasm

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muscarinic receptor kinase

Papers overview

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Review
2009
Review
2009
GRK mythology: G-protein receptor kinases in cardiovascular disease
G-protein receptor kinases (GRKs) are indispensable for terminating signaling of G-protein coupled receptors (GPCR) through… 
2008
2008
Characterization of G-Protein Coupled Receptor Kinase Interaction with the Neurokinin-1 Receptor Using Bioluminescence Resonance Energy Transfer
To analyze the interaction between the neurokinin-1 (NK-1) receptor and G-protein coupled receptor kinases (GRKs), we performed… 
Highly Cited
2004
Highly Cited
2004
Antidiabetic effect of novel modulating peptides of G-protein-coupled kinase in experimental models of diabetes
Aims/hypothesisG-protein-coupled receptor kinases (GRKs) play a key role in agonist-induced desensitisation of G-protein-coupled… 
2003
2003
The association of arrestin-3 with the follitropin receptor depends on receptor activation and phosphorylation
2002
2002
Induction of G protein-coupled receptor kinases 2 and 3 contributes to the cross-talk between μ and ORL1 receptors following prolonged agonist exposure
2001
2001
Concomitant Increase of G Protein-Coupled Receptor Kinase Activity and Uncoupling of β-Adrenergic Receptors in Rat Myometrium at Parturition.
The myometrial β-adrenergic receptor (β-AR)-adenylyl cyclase pathway is markedly desensitized at the end of pregnancy in the rat… 
2000
2000
Retrovirally Mediated Transfer of a G Protein-coupled Receptor Kinase (GRK) Dominant-negative Mutant Enhances Endogenous Calcitonin Receptor Signaling in Chinese Hamster Ovary Cells
G protein-coupled receptor kinases (GRKs) initiate pathways leading to agonist-dependent phosphorylation and desensitization of G… 
Highly Cited
1998
Highly Cited
1998
The Solution Structure and Dynamics of the Pleckstrin Homology Domain of G Protein-coupled Receptor Kinase 2 (β-Adrenergic Receptor Kinase 1)
The solution structure of an extended pleckstrin homology (PH) domain from the β-adrenergic receptor kinase is obtained by high… 
Highly Cited
1998
Highly Cited
1998
Localization of the sites for Ca2+-binding proteins on G protein-coupled receptor kinases.
Inhibition of G protein-coupled receptor kinases (GRKs) by Ca2+-binding proteins has recently emerged as a general mechanism of… 
1994
1994
An approach to the study of G-protein-coupled receptor kinases: an in vitro-purified membrane assay reveals differential receptor specificity and regulation by G beta gamma subunits.
Phosphorylation of GTP-binding-regulatory (G)-protein-coupled receptors by specific G-protein-coupled receptor kinases (GRKs) is… 
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