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ADRBK1 wt Allele
Known as:
BARK1
, GRK2
, Adrenergic, Beta, Receptor Kinase 1 wt Allele
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Human ADRBK1 wild-type allele is located within 11q13 and is approximately 20 kb in length. This allele, which encodes beta-adrenergic receptor…
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National Institutes of Health
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Related topics
Related topics
10 relations
11q13
Beta-Adrenergic Receptor Kinase 1
G Protein-Coupled Receptor Signaling
GPCR Signaling Pathway
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Broader (1)
ADRBK1 gene
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
2016
2016
Myocardial function after polarizing versus depolarizing cardiac arrest with blood cardioplegia in a porcine model of cardiopulmonary bypass†
T. Aass
,
L. Stangeland
,
+9 authors
K. Grong
European Journal of Cardio-Thoracic Surgery
2016
Corpus ID: 4918822
OBJECTIVES Potassium-based depolarizing St Thomas' Hospital cardioplegic solution No 2 administered as intermittent, oxygenated…
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2015
2015
GRK2 Targeted Knock-down Results in Spontaneous Hypertension, and Altered Vascular GPCR Signaling*
E. Tutunea-Fatan
,
Fabiana A. Caetano
,
R. Gros
,
S. Ferguson
Journal of Biological Chemistry
2015
Corpus ID: 38479794
Background: GRK2 contributes to the desensitization of GPCRs is involved in cardiovascular disease. Results: Genetic knockdown of…
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2012
2012
GRK2 at the control shaft of cellular metabolism.
M. Ciccarelli
,
E. Cipolletta
,
Guido Iaccarino
Current pharmaceutical design
2012
Corpus ID: 24698574
G protein receptor kinase 2 (GRK2) has been for years mainly considered the negative regulator of the cardiac β adrenergic…
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Review
2011
Review
2011
Microglial GRK2: A novel regulator of transition from acute to chronic pain
A. Kavelaars
,
N. Eijkelkamp
,
H. Willemen
,
Huijing Wang
,
A. G. Carbajal
,
C. Heijnen
Brain, behavior, and immunity
2011
Corpus ID: 33536948
2010
2010
Combining resonance energy transfer methods reveals a complex between the alpha2A-adrenergic receptor, Galphai1beta1gamma2, and GRK2.
B. Breton
,
M. Lagacé
,
M. Bouvier
The FASEB Journal
2010
Corpus ID: 3176205
Traditionally, G-protein-coupled receptor (GPCR) interactions with their G proteins and regulatory proteins, GPCR kinases (GRKs…
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2009
2009
Regulation of G-Protein Signaling by RKTG via Sequestration of the Gβγ Subunit to the Golgi Apparatus
Yuhui Jiang
,
Xiaoduo Xie
,
+6 authors
Yan Chen
Molecular and Cellular Biology
2009
Corpus ID: 22088957
ABSTRACT Upon ligand binding, G-protein-coupled receptors (GPCRs) impart the signal to heterotrimeric G proteins composed of…
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2008
2008
Characterization of G-Protein Coupled Receptor Kinase Interaction with the Neurokinin-1 Receptor Using Bioluminescence Resonance Energy Transfer
Rasmus Jorgensen
,
N. Holliday
,
+4 authors
C. Elling
Molecular Pharmacology
2008
Corpus ID: 26300801
To analyze the interaction between the neurokinin-1 (NK-1) receptor and G-protein coupled receptor kinases (GRKs), we performed…
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2002
2002
Induction of G protein-coupled receptor kinases 2 and 3 contributes to the cross-talk between μ and ORL1 receptors following prolonged agonist exposure
D. Thakker
,
K. Standifer
Neuropharmacology
2002
Corpus ID: 7962481
1999
1999
The Amino Terminus with a Conserved Glutamic Acid of G Protein‐Coupled Receptor Kinases Is Indispensable for Their Ability to Phosphorylate Photoactivated Rhodopsin
Qingming Yu
,
Zhi-jie Cheng
,
Xiaoqing Gan
,
Guo‐Bin Bao
,
Lin Li
,
G. Pei
Journal of Neurochemistry
1999
Corpus ID: 12400621
Abstract : To investigate functions of the consensus amino terminus of G protein‐coupled receptor kinases (GRKs), two amino…
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1999
1999
Effect of G Protein‐Coupled Receptor Kinase 2 on the Sensitivity of M4 Muscarinic Acetylcholine Receptors to Agonist‐Induced Internalization and Desensitization in NG108‐15 Cells
E. Holroyd
,
P. Szekeres
,
R. D. Whittaker
,
E. Kelly
,
J. Edwardson
Journal of Neurochemistry
1999
Corpus ID: 23607876
Abstract : NG108‐15 cells express predominantly the M4 subtype of the muscarinic receptor for acetylcholine. Stimulation of these…
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