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RELA protein, human
Known as:
Nuclear Factor Kappa-B Subunit 3
, Transcription Factor NFKB3
, NFkappaB p65 Subunit
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Transcription factor p65 (551 aa, ~60 kDa) is encoded by the human RELA gene. This protein is involved in the modulation of both signaling and gene…
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National Institutes of Health
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Related topics
Related topics
37 relations
AKT Signaling Pathway
ATM Signaling Pathway
Adipocytokine Signaling Pathway
Apoptosis
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Broader (1)
Transcription Factor RelA
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2011
Highly Cited
2011
The RelA/SpoT Homolog (RSH) Superfamily: Distribution and Functional Evolution of ppGpp Synthetases and Hydrolases across the Tree of Life
G. Atkinson
,
T. Tenson
,
V. Hauryliuk
PloS one
2011
Corpus ID: 14173628
RelA/SpoT Homologue (RSH) proteins, named for their sequence similarity to the RelA and SpoT enzymes of Escherichia coli…
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Highly Cited
2008
Highly Cited
2008
RelA Ser276 Phosphorylation Is Required for Activation of a Subset of NF-κB-Dependent Genes by Recruiting Cyclin-Dependent Kinase 9/Cyclin T1 Complexes
D. E. Nowak
,
B. Tian
,
+4 authors
A. Brasier
Molecular and Cellular Biology
2008
Corpus ID: 44288376
ABSTRACT NF-κB plays a central role in cytokine-inducible inflammatory gene expression. Previously we empirically determined the…
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Highly Cited
2007
Highly Cited
2007
COMMD1 promotes the ubiquitination of NF‐κB subunits through a cullin‐containing ubiquitin ligase
G. Maine
,
X. Mao
,
Christine M. Komarck
,
E. Burstein
The EMBO journal
2007
Corpus ID: 20853824
NF‐κB is a pleiotropic transcription factor involved in multiple processes, including inflammation and oncogenesis. We have…
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Review
2006
Review
2006
Roles for NF-kappaB in nerve cell survival, plasticity, and disease.
M. Mattson
,
M. Meffert
Cell death and differentiation
2006
Corpus ID: 40989754
Here we review evidence of roles for NF-kappaB in the regulation of developmental and synaptic plasticity, and cell survival in…
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Highly Cited
2004
Highly Cited
2004
Commensal anaerobic gut bacteria attenuate inflammation by regulating nuclear-cytoplasmic shuttling of PPAR-γ and RelA
D. Kelly
,
J. Campbell
,
+5 authors
S. Conway
Nature Immunology
2004
Corpus ID: 20250135
The human gut microflora is important in regulating host inflammatory responses and in maintaining immune homeostasis. The…
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Highly Cited
2004
Highly Cited
2004
Active repression of antiapoptotic gene expression by RelA(p65) NF-kappa B.
K. Campbell
,
S. Rocha
,
N. Perkins
Molecular cell
2004
Corpus ID: 33721284
With the emerging role of NF-kappa B in cancer it is important that its responses to stimuli relevant to tumor progression and…
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Highly Cited
2002
Highly Cited
2002
Acetylation of RelA at discrete sites regulates distinct nuclear functions of NF‐κB
Lin-Feng Chen
,
Y. Mu
,
W. Greene
The EMBO journal
2002
Corpus ID: 36859186
The nuclear function of the heterodimeric NF‐κB transcription factor is regulated in part through reversible acetylation of its…
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Highly Cited
2002
Highly Cited
2002
Dissection of the mechanism for the stringent factor RelA.
T. Wendrich
,
G. Blaha
,
Daniel N. Wilson
,
M. Marahiel
,
K. Nierhaus
Molecular cell
2002
Corpus ID: 25475970
Highly Cited
1996
Highly Cited
1996
Mutual Transcriptional Interference between RelA and Androgen Receptor*
J. Palvimo
,
Piia Reinikainen
,
T. Ikonen
,
P. Kallio
,
A. Moilanen
,
O. Jänne
The Journal of Biological Chemistry
1996
Corpus ID: 34671795
Cross-modulation between androgen receptor (AR) and NF-κB/Rel proteins was studied using various androgen- and NF-κB-regulated…
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Highly Cited
1994
Highly Cited
1994
An interaction between the DNA-binding domains of RelA(p65) and Sp1 mediates human immunodeficiency virus gene activation.
N. Perkins
,
A. B. Agranoff
,
E. Pascal
,
G. Nabel
Molecular and cellular biology
1994
Corpus ID: 1812683
Induction of human immunodeficiency virus type 1 (HIV-1) gene expression in stimulated T cells has been attributed to the…
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