Protein Jagged-1, human

Known as: Jagged protein, human, jagged 1 (Alagille syndrome) protein, human, jagged 1 protein, human 
Protein jagged-1 (1218 aa, ~134 kDa) is encoded by the human JAG1 gene. This protein may be involved in the development of the hematopoietic system.
National Institutes of Health

Topic mentions per year

Topic mentions per year

1996-2018
020406019962018

Papers overview

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Highly Cited
2011
Highly Cited
2011
Despite evidence supporting an oncogenic role in breast cancer, the Notch pathway's contribution to metastasis remains unknown… (More)
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Highly Cited
2006
Highly Cited
2006
Each of the sensory patches in the epithelium of the inner ear is a mosaic of hair cells and supporting cells. Notch signalling… (More)
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Highly Cited
2005
Highly Cited
2005
Stem cells reside in a specialized niche that regulates their abundance and fate. Components of the niche have generally been… (More)
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Highly Cited
2004
Highly Cited
2004
Epithelial-to-mesenchymal transitions (EMTs) underlie cell plasticity required in embryonic development and frequently observed… (More)
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Highly Cited
2004
Highly Cited
2004
The Delta-Notch signaling pathway plays a central role in the development of most vertebrate organs. The Hey family of bHLH… (More)
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Highly Cited
2002
Highly Cited
2002
Notch signaling controls cell fate decisions of hematopoietic progenitors by inhibiting certain steps of differentiation and… (More)
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Highly Cited
1999
Highly Cited
1999
The Notch signaling pathway is an evolutionarily conserved intercellular signaling mechanism essential for embryonic development… (More)
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Highly Cited
1998
Highly Cited
1998
In this study, we show that oligodendrocyte differentiation is powerfully inhibited by activation of the Notch pathway… (More)
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Highly Cited
1997
Highly Cited
1997
Alagille syndrome is an autosomal dominant disorder characterized by abnormal development of liver, heart, skeleton, eye, face… (More)
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Highly Cited
1997
Highly Cited
1997
Alagille syndrome (AGS) is an autosomal-dominant disorder characterized by intrahepatic cholestasis and abnormalities of heart… (More)
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