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Jagged-1 Protein
Known as:
CD339 Antigen
, Alagille Syndrome Protein
, Jagged 1
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A serrate-jagged protein that functions as a ligand for NOTCH RECEPTORS. It may regulate CELL DIFFERENTIATION in HEMATOPOIESIS and PHYSIOLOGIC…
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National Institutes of Health
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Related topics
Related topics
12 relations
In Blood
JAG1 gene
JAG1 wt Allele
Process of secretion
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Narrower (2)
Jag1 protein, mouse
Protein Jagged-1, human
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
2012
2012
Overexpression of Angiopoietin-1 Increases CD133+/c-kit+ Cells and Reduces Myocardial Apoptosis in db/db Mouse Infarcted Hearts
H. Zeng
,
Lanfang Li
,
Jian‐Xiong Chen
PLoS ONE
2012
Corpus ID: 17861772
Hematopoietic progenitor CD133+/c-kit+ cells have been shown to be involved in myocardial healing following myocardial infarction…
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Highly Cited
2011
Highly Cited
2011
Mesenchymal stromal cells affect cardiomyocyte growth through juxtacrine Notch-1/Jagged-1 signaling and paracrine mechanisms: clues for cardiac regeneration.
C. Sassoli
,
A. Pini
,
+6 authors
L. Formigli
Journal of Molecular and Cellular Cardiology
2011
Corpus ID: 42509561
Highly Cited
2011
Highly Cited
2011
Restored expression of the tumor suppressor gene RUNX3 reduces cancer stem cells in hepatocellular carcinoma by suppressing Jagged1-Notch signaling.
Shin-ichi Nishina
,
H. Shiraha
,
+9 authors
Kazuhide Yamamoto
Oncology Report
2011
Corpus ID: 22554306
Runt-related transcription factor 3 (RUNX3) is a candidate tumor suppressor gene that is downregulated in various cancers. In the…
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2010
2010
Adult epidermal Notch activity induces dermal accumulation of T cells and neural crest derivatives through upregulation of jagged 1
C. Ambler
,
F. Watt
Development
2010
Corpus ID: 21436137
Notch signalling regulates epidermal differentiation and tumour formation via non-cell autonomous mechanisms that are…
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2009
2009
Induction of notch signaling by immobilization of jagged-1 on self-assembled monolayers.
R. Gonçalves
,
M. Cristina L. Martins
,
G. Almeida-Porada
,
Mário A. Barbosa
Biomaterials
2009
Corpus ID: 5517758
Highly Cited
2008
Highly Cited
2008
Human immature myeloid dendritic cells trigger a TH2-polarizing program via Jagged-1/Notch interaction.
F. Liotta
,
Francesca Frosali
,
+16 authors
F. Annunziato
Journal of Allergy and Clinical Immunology
2008
Corpus ID: 2300484
2007
2007
The intracellular region of the Notch ligand Jagged‐1 gains partial structure upon binding to synthetic membranes
Matija Popovic
,
A. De Biasio
,
A. Pintar
,
S. Pongor
The FEBS Journal
2007
Corpus ID: 45497888
Notch ligands are membrane‐spanning proteins made of a large extracellular region, a transmembrane segment, and a ∼ 100–200…
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Highly Cited
2006
Highly Cited
2006
Retracted: Down‐regulation of Jagged‐1 induces cell growth inhibition and S phase arrest in prostate cancer cells
Yuxiang Zhang
,
Zhiwei Wang
,
Fakhara Ahmed
,
Sanjeev Banerjee
,
Yiwei Li
,
F. Sarkar
International Journal of Cancer
2006
Corpus ID: 41714300
This article has been retracted at the request of: Editor‐in‐Chief and Co‐author
Highly Cited
2004
Highly Cited
2004
Soluble Jagged‐1 is able to inhibit the function of its multivalent form to induce hematopoietic stem cell self‐renewal in a surrogate in vitro assay
V. Vas
,
L. Szilágyi
,
K. Pálóczi
,
F. Uher
Journal of Leukocyte Biology
2004
Corpus ID: 25227818
Stem cells reside in customized microenvironments (niches) that contribute to their unique ability to divide asymmetrically to…
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2002
2002
The Soluble Notch Ligand, Jagged-1, Inhibits Proliferation of CD34+ Macrophage Progenitors
M. Masuya
,
N. Katayama
,
+10 authors
H. Shiku
International journal of hematology
2002
Corpus ID: 25028414
The Notch/Notch ligand system controls diverse cellular processes. The proteolytic cleavage generates transmembrane and soluble…
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