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Properdin
Known as:
Complement factor P
, Factor P, Complement
, factor P
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A 53-kDa protein that is a positive regulator of the alternate pathway of complement activation (COMPLEMENT ACTIVATION PATHWAY, ALTERNATIVE). It…
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National Institutes of Health
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Related topics
Related topics
15 relations
CFP gene
Complement Pathway, Alternative
Process of secretion
agonists
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Broader (2)
Gamma globulin
Immunologic Factors
Narrower (3)
Human Properdin
PROPERDIN DEFICIENCY, X-LINKED
properdistatin
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
1996
1996
Key role of the alternate complement pathway in hyperacute rejection of rat hearts transplanted into fetal sheep.
H. Rajasinghe
,
V. Reddy
,
W. Hancock
,
M. Sayegh
,
F. Hanley
Transplantation
1996
Corpus ID: 24679652
Hyperacute rejection (HAR) mediated by xenoreactive natural antibodies (XNA), which are thought to develop in early infancy, is a…
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1984
1984
Inhibition of the function of activated properdin by squid chondroitin sulfate E glycosaminoglycan and murine bone marrow-derived mast cell chondroitin sulfate E proteoglycan.
J. G. Wilson
,
D. Fearon
,
R. Stevens
,
N. Seno
,
K. Austen
Journal of Immunology
1984
Corpus ID: 23904812
We compared the relative capacities of two over-sulfated glycosaminoglycans, heparin and chondroitin sulfate E, to alter the…
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1983
1983
Surface-dependent modulation by H of C5 cleavage by the cell-bound alternative pathway C5 convertase of human complement.
E. Fischer
,
M. Kazatchkine
Journal of Immunology
1983
Corpus ID: 38800120
Regulation by H of formation of the C3 and C5 alternative pathway convertases of complement on cells is dependent on such…
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1981
1981
The conversion of human complement component C5 into fragment C5b by the alternative-pathway C5 convertase.
R. Discipio
Biochemical Journal
1981
Corpus ID: 44996156
The cleavage of human complement component C5 to fragment C5b by the alternative pathway C5 convertase was studied. The…
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1978
1978
Hereditary C2 deficiency and systemic lupus erythematosus associated with severe glomerulonephritis.
J. Roberts
,
M. Schwartz
,
E. Lewis
Clinical and Experimental Immunology
1978
Corpus ID: 37105293
Although an unusually high incidence of immunological diseases has been described in patients with hereditary C2 deficiency, the…
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1976
1976
Effect of proteolytic digestion on the structure and function of human properdin.
J. Minta
,
E. S. Kunar
Journal of Immunology
1976
Corpus ID: 21010479
Human properdin (P) was found to be sensitive to the action of trypsin, chymotrypsin, pepsin, and Streptomycetes caesipitosus…
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1976
1976
Complement activation in semi-solid medium: Insolubilization of properdin and the third component of complement (C3) in agar gels.
J. Ziegler
,
L. Watson
,
I. Goodkofsky
,
C. Alper
,
I. Lepow
Journal of Immunology
1976
Corpus ID: 41182307
Although the role of properdin in the alternative pathway of complement activation remains unclear, evidence has recently been…
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1958
1958
DIFFERENTIAL EFFECT OF HOG GASTRIC MUCIN ON PROPERDIN AND HOST RESISTANCE TO INFECTION
C. Dewitt
Journal of Bacteriology
1958
Corpus ID: 13303716
It is generally recognized that hog gastric mucin is capable of markedlv increasing the apparent virulence of many bacteria…
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1958
1958
Studies on the properdin system in rats bearing the transplantable human carcinoma HR132.
P. Herbut
,
W. H. Kraemer
,
L. Pillemer
,
E. W. Todd
Cancer Research
1958
Corpus ID: 23304635
The hypothesis that the properdin system may play a role in the natural resistance of animals to transplantable tumors was…
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1958
1958
The effects of components of guinea pig serum on lymphosarcoma 6C3HED in C3H mice.
P. Herbut
,
W. H. Kraemer
,
L. Pillemer
Blood
1958
Corpus ID: 1252918
The effects of various preparations of guinea pig serum on the Gardner lymphosarcoma 6C3HED in C3H mice were studied. Complete…
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