Properdin

Known as: Factor P, Complement, Complement Factor P, factor P 
A 53-kDa protein that is a positive regulator of the alternate pathway of complement activation (COMPLEMENT ACTIVATION PATHWAY, ALTERNATIVE). It… (More)
National Institutes of Health

Topic mentions per year

Topic mentions per year

1954-2017
0204019542016

Papers overview

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2008
2008
Properdin is a positive regulator of complement activation so far known to be instrumental in the survival of infections with… (More)
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Highly Cited
2008
Highly Cited
2008
Apoptotic cells must be rapidly eliminated to avoid harmful inflammatory and autoimmune reactions. Innate immunity is designed… (More)
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Highly Cited
2007
Highly Cited
2007
Complement promotes the rapid recognition and elimination of pathogens, infected cells, and immune complexes. The biochemical… (More)
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Highly Cited
1997
Highly Cited
1997
Properdin is an important regulatory constituent of the complement system. In contrast to most other components of complement… (More)
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1994
1994
Properdin is the only known positive regulator of the alternative pathway of complement activation. Northern blot analysis of… (More)
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Highly Cited
1977
Highly Cited
1977
Bacterial lipopolysaccharides (LPS) have been demonstrated to activate both the classical and the properdin pathways of… (More)
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Highly Cited
1976
Highly Cited
1976
C3b inactivator accelerator (A-C3bINA) was isolated from human plasma. An antiserum produced against the purified protein gave a… (More)
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Highly Cited
1975
Highly Cited
1975
A function of P in the alternative complement pathway is to prolong the first order decay of the hemolytic sites on EAC43B in a… (More)
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1956
1956
I t has recently been shown that a variety of high molecular weight polysaccharides or polysaccharide complexes combine with… (More)
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1956
1956
A detailed method for the zymosan assay of properdin is described, together with procedures for the preparation and… (More)
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