Human Properdin

Known as: Complement Factor P, Factor P, Properdin 
Properdin (469 aa, ~51 kDa) is encoded by the human CFP gene. This protein plays a role in the stabilization of complement convertases of the… (More)
National Institutes of Health

Topic mentions per year

Topic mentions per year

1953-2018
051019532017

Papers overview

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2011
2011
Activation of complement represents one means of natural resistance to infection from a wide variety of potential pathogens… (More)
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2010
2010
Properdin, a positive regulator of the complement system, has recently been reported to bind to certain pathogenic microorganisms… (More)
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Highly Cited
2008
Highly Cited
2008
Properdin is a positive regulator of alternative pathway (AP) complement. The current understanding of properdin function is that… (More)
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2000
2000
Nascent C3b can form ester bonds with various target molecules on the cell surface and in the fluid phase. Previously, we showed… (More)
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2000
2000
Properdin is the positive regulator of the alternative pathway of complement activation. The 53-kDa protein is essentially… (More)
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1994
1994
Properdin is the only known positive regulator of the alternative pathway of complement activation. Northern blot analysis of… (More)
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1989
1989
Many of the anomalies observed in studies or properdin may be explained on the basis of its ability to form a series of multi… (More)
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1984
1984
The structure of the human properdin molecule was investigated by hydrodynamic, spectroscopic, and transmission electron… (More)
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1979
1979
Summary: Levels of eight complement components and two control proteins, were determined on cord serum from normal full term… (More)
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1974
1974
The activity of properdin factor D was measured by the generation of the hemolytically active cellular intermediate, EAC43B(D… (More)
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