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Human Properdin

Known as: Complement Factor P, Factor P, Properdin 
Properdin (469 aa, ~51 kDa) is encoded by the human CFP gene. This protein plays a role in the stabilization of complement convertases of the… 
National Institutes of Health

Related topics

Related topics

8 relations
CFP geneCFP wt AlleleComplement ActivationComplement Pathway, Alternative

Broader (1)

Properdin

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
1987
1987
Bactericidal activity for Neisseria meningitidis in properdin-deficient sera.
We investigated serum bactericidal reactions against Neisseria meningitidis (serogroups A, B, C, D, Y, W-135, 29E, X, and Z) in… 
1984
1984
Mapping of the properdin-binding site in the third component of complement.
The properdin-binding site in the human third complement component (C3) was mapped by using isolated C3b, C3c, alpha- and beta… 
1980
1980
The rabbit properdin system: I. Identification of a new factor and purification of rabbit properdin.
Pure preparations of rabbit properdin were obtained from rabbit serum by ion-exchange chromatography. These preparations… 
1978
1978
Homozygous C2 deficiency with fulminant lupus erythematosus: severe nephritis via the alternative complement pathway.
Absence of C2 was identified in an 18-year-old white male with progressive and rapidly fatal lupus nephritis. Genetic studies of… 
1977
1977
C3 and C5-cleaving properdin enzymes formed on zymosan incubated with human serum: the decay and the regeneration of the enzymes.
Incubation os zymosan (Z) with normal human serum led to the formation of ZXhu, which had the abilities to cleave C3 and C5… 
1976
1976
Purification of native properdin by reversed affinity chromatography and its activation by proteolytic enzymes.
A highly purified preparation of human properdin (P) has been obtained in a simple two-step procedure utilizing reversed… 
1975
1975
Cleavage of the third complement component (C3) and generation of the spasmogenic peptide, C3a, in human serum via the properdin pathway: demonstration of inhibitory as well as enhancing effects of…
Human and guinea pig serum loses hemolytic activity of the third complement component (C3) during incubation at 37 degrees C. The… 
1975
1975
Changes in the immunochemical properties of highly purified properdin in human serum.
The fate of highly purified properdin (P) upon introduction into normal human serum or properdin-depleted serum (RP) was… 
1973
1973
Determination of serum properdin levels by immunodiffusion.
The measurement of properdin in human serum can be easily carried out by the Mancini method using antiserum to purified properdin… 
1963
1963
Non-specific resistance of the organism against environmental insults; with special reference to the reticuloendothelial system and properdin system.
It is well known that prior inoculation of animals with some bacterial products and bacterial components quickly endows them with…