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Human Properdin

Known as: Complement Factor P, Factor P, Properdin 
Properdin (469 aa, ~51 kDa) is encoded by the human CFP gene. This protein plays a role in the stabilization of complement convertases of the… Expand
National Institutes of Health

Papers overview

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2017
2017
Significance The role of properdin in stabilization of the alternative pathway C3 convertase is indisputable, whereas its role as… Expand
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Highly Cited
2013
Highly Cited
2013
Elevated numbers of activated platelets circulate in patients with chronic inflammatory diseases, including atherosclerosis and… Expand
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Highly Cited
2010
Highly Cited
2010
Properdin, a positive regulator of the complement system, has recently been reported to bind to certain pathogenic microorganisms… Expand
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Highly Cited
2010
Highly Cited
2010
Properdin, a positive regulator of the alternative pathway (AP) of complement is important in innate immune defenses against… Expand
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Highly Cited
2008
Highly Cited
2008
Properdin is a positive regulator of alternative pathway (AP) complement. The current understanding of properdin function is that… Expand
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Highly Cited
2000
Highly Cited
2000
Properdin is the positive regulator of the alternative pathway of complement activation. The 53-kDa protein is essentially… Expand
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Highly Cited
1989
Highly Cited
1989
Many of the anomalies observed in studies or properdin may be explained on the basis of its ability to form a series of multi… Expand
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Highly Cited
1984
Highly Cited
1984
The structure of the human properdin molecule was investigated by hydrodynamic, spectroscopic, and transmission electron… Expand
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Highly Cited
1979
Highly Cited
1979
Summary: Levels of eight complement components and two control proteins, were determined on cord serum from normal full term… Expand
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1956
1956
Methods for the preparation and standardization of reagents suitable for studies on the bactericidal action of the properdin… Expand
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