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Propantheline
Known as:
2-Propanaminium, N-methyl-N-(1-methylethyl)-N-(2-((9H-xanthen-9-ylcarbonyl)oxy)ethyl)-
, Propantheline [Chemical/Ingredient]
A muscarinic antagonist used as an antispasmodic, in rhinitis, in urinary incontinence, and in the treatment of ulcers. At high doses it has…
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National Institutes of Health
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Related topics
Related topics
25 relations
Angle Closure Glaucoma
Hypersensitivity
In Blood
Intestinal Obstruction
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Broader (2)
Anti-Ulcer Agent
Muscarinic Antagonists
Narrower (3)
Dolo-Tensilan
Probanthine
pukeling
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
Review
2013
Review
2013
Prevention of oral mucositis in children receiving cancer therapy: a systematic review and evidence-based analysis.
A. Qutob
,
S. Gue
,
T. Révész
,
R. Logan
,
D. Keefe
Oral Oncology
2013
Corpus ID: 35518403
2002
2002
An improved method of evaluation of drug-evoked changes in gastric emptying in mice.
M. Osinski
,
T. Seifert
,
Bryan F. Cox
,
G. Gintant
Journal of pharmacological and toxicological…
2002
Corpus ID: 25834095
Highly Cited
1994
Highly Cited
1994
Pharmacological modulation of gastric emptying rate of solids as measured by the carbon labelled octanoic acid breath test: influence of erythromycin and propantheline.
B. Maes
,
M. Hiele
,
B. Geypens
,
P. Rutgeerts
,
Y. Ghoos
,
G. Vantrappen
Gut
1994
Corpus ID: 6699988
The *C (13C or 14C) labelled octanoic acid breath test was recently developed to measure the gastric emptying rate of solids…
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Highly Cited
1991
Highly Cited
1991
Randomized, double-blind, multicenter trial on treatment of frequency, urgency and incontinence related to detrusor hyperactivity: oxybutynin versus propantheline versus placebo.
J. W. Thüroff
,
Björn Bunke
,
+9 authors
M. Stöckle
Journal of Urology
1991
Corpus ID: 23568640
Highly Cited
1988
Highly Cited
1988
External sphincter dyssynergia: an abnormal continence reflex.
D. Rudy
,
Said A. Awad
,
J. Downie
Journal of Urology
1988
Corpus ID: 29068671
Highly Cited
1987
Highly Cited
1987
Micturition and the mind: psychological factors in the aetiology and treatment of urinary symptoms in women.
A. Macaulay
,
R. S. Stern
,
D. M. Holmes
,
S. L. Stanton
British medical journal
1987
Corpus ID: 23044615
The mental state of 211 women attending a urodynamic clinic was assessed using questionnaires. Patients with genuine stress…
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Review
1982
Review
1982
Drug Interactions with Cimetidine
A. Somogyi
,
R. Gugler
Clinical Pharmacokinetics
1982
Corpus ID: 36937891
SummaryBecause of widespread (and often uncritical) use of Cimetidine, there is considerable potential for interactions to occur…
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Highly Cited
1977
Highly Cited
1977
Effect of low-dose propantheline on food-stimulated gastric acid secretion: comparison with an "optimal effective dose" and interaction with cimetidine.
M. Feldman
,
C. T. Richardson
,
W. Peterson
,
J. Walsh
,
J. Fordtran
New England Journal of Medicine
1977
Corpus ID: 11410926
We evaluated the widely held notion that anticholinergic drugs must be used in near toxic doses to inhibit gastric acid secretion…
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Highly Cited
1973
Highly Cited
1973
Pharmacological Modification of Gastric Emptying: Effects of Propantheline and Metoclopromide on Paracetamol Absorption
C. London
,
R. Greenhalgh
,
+8 authors
L. Prescott
British medical journal
1973
Corpus ID: 14446399
The rate of paracetamol absorption depends on the rate of gastric emptying. Propantheline delayed gastric emptying and markedly…
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1972
1972
On the metabolism of propantheline in man
B. Beermann
,
K. Hellström
,
A. Rosén
Clinical pharmacology and therapy
1972
Corpus ID: 42520188
Propantheline, 60 mg., labeled with 14C in its xanthene carboxylic moiety, was given orally or intrajejunally to 5 healthy…
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