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A systematic computational method predicts new uses for existing drugs by integrating public gene expression signatures of drugs… Expand The polymorphic nature of the cytochrome P450 (CYP) genes affects individual drug response and adverse reactions to a great… Expand This paper describes development, optimization and validation of a method for the simultaneous determination of 29 multi-class… Expand Four types of experimental chronic ulcer models, named acetic acid ulcer models, have been developed to examine the healing… Expand The discovery of Helicobacter pylori has greatly changed our approach to peptic ulcer disease. Bacterial, host, and environmental… Expand BACKGROUND & AIMS
An antiulcer drug, geranylgeranylacetone (GGA), rapidly induces resistance of gastric mucosal cells to… Expand Approximately 14 million patients in the United States regularly take nonsteroidal anti-inflammatory drugs(NSAIDs) for various… Expand The activities of various types of antiulcer agents against Helicobacter pylori (formerly called Campylobacter pylori) strains… Expand Effects of KB-5492, a new anti-ulcer agent, on various experimental gastric mucosal lesions and mucosal defensive factors in rats… Expand Various procedures have been reported on the biossay of antiulcer drugs . Pylorus ligation of the rat (1-3), restraint of the rat… Expand