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Prohormone Convertases

Known as: Convertase, Prohormone, Convertases, Prohormone, Prohormone Convertase 
National Institutes of Health

Related topics

Related topics

5 relations

Narrower (3)

Proprotein Convertase 1Proprotein Convertase 2paired basic amino acid cleaving enzyme

Broader (2)

Proprotein ConvertasesSerine Proteases

Papers overview

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Highly Cited
2010
Highly Cited
2010
Modulation of glucagon-like peptide-1 release by berberine: in vivo and in vitro studies.
2008
2008
7B2 prevents unfolding and aggregation of prohormone convertase 2.
Prohormone convertase 2 (PC2) requires interaction with the neuroendocrine protein 7B2 for the production of an activatable… 
Highly Cited
2006
Highly Cited
2006
Impaired NH2-Terminal Processing of Human Proislet Amyloid Polypeptide by the Prohormone Convertase PC2 Leads to Amyloid Formation and Cell Death
Islet amyloid, formed by aggregation of islet amyloid polypeptide (IAPP; amylin), is a pathological characteristic of the… 
Highly Cited
2005
Highly Cited
2005
Proprotein convertase models based on the crystal structures of furin and kexin: explanation of their specificity.
Highly Cited
2000
Highly Cited
2000
Defective Prodynorphin Processing in Mice Lacking Prohormone Convertase PC2
Abstract: Prodynorphin, a multifunctional precursor of several important opioid peptides, is expressed widely in the CNS. It is… 
Highly Cited
2000
Highly Cited
2000
The C-terminal Region of proSAAS Is a Potent Inhibitor of Prohormone Convertase 1*
ProSAAS is a recently discovered 26-kDa neuroendocrine protein that was previously found to inhibit prohormone convertase (PC) 1… 
Highly Cited
1997
Highly Cited
1997
Role of the Prohormone Convertase PC3 in the Processing of Proglucagon to Glucagon-like Peptide 1*
Proglucagon is processed differentially in pancreatic α-cells and intestinal endocrine L cells to release either glucagon or… 
Highly Cited
1996
Highly Cited
1996
Purification and enzymatic characterization of recombinant prohormone convertase 2: stabilization of activity by 21 kDa 7B2.
Although previous efforts to produce significant quantities of purified prohormone convertase 2 from either recombinant or… 
Highly Cited
1994
Highly Cited
1994
Proglucagon is processed to glucagon by prohormone convertase PC2 in alpha TC1-6 cells.
Proglucagon is processed differentially in the pancreatic alpha cells and the intestinal L cells to yield either glucagon or… 
Highly Cited
1992
Highly Cited
1992
Biosynthesis of the prohormone convertase mPC1 in AtT-20 cells.
A new family of mammalian subtilisin-like enzymes, probably involved in the processing of proproteins in regulated and… 
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