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Prohormone Convertases
Known as:
Convertase, Prohormone
, Convertases, Prohormone
, Prohormone Convertase
Â
Â
Topic mentions per year
Topic mentions per year
1991-2017
0
10
20
1991
2017
Related topics
Related topics
5 relations
Narrower (3)
Proprotein Convertase 1
Proprotein Convertase 2
paired basic amino acid cleaving enzyme
Broader (2)
Proprotein Convertases
Serine Proteases
Related mentions per year
Related mentions per year
1969-2018
1960
1980
2000
2020
Prohormone Convertases
Serine Proteases
paired basic amino acid cleaving enzyme
Proprotein Convertases
Proprotein Convertase 2
Proprotein Convertase 1
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2007
Highly Cited
2007
Hyperphagia and early-onset obesity due to a novel homozygous missense mutation in prohormone convertase 1/3.
I Sadaf Farooqi
,
Karolien Volders
,
+6 authors
John W. M. Creemers
The Journal of clinical endocrinology and…
2007
CONTEXT Congenital deficiency of the neuroendocrine-specific enzyme prohormone convertase (PC) 1/3 leads to a syndrome…Â
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2006
2006
Impaired NH2-terminal processing of human proislet amyloid polypeptide by the prohormone convertase PC2 leads to amyloid formation and cell death.
Lucy Marzban
,
Christopher J. Rhodes
,
Donald F. Steiner
,
Leena Haataja
,
Philippe A. Halban
,
C. Bruce Verchere
Diabetes
2006
Islet amyloid, formed by aggregation of islet amyloid polypeptide (IAPP; amylin), is a pathological characteristic of the…Â
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2001
2001
Impaired prohormone convertases in Cpe(fat)/Cpe(fat) mice.
Yemiliya Berman
,
Nino Mzhavia
,
Ann Polonskaia
,
Lavany Devi
The Journal of biological chemistry
2001
A spontaneous point mutation in the coding region of the carboxypeptidase E (CPE) gene results in a loss of CPE activity that…Â
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2001
2001
The prohormone convertase enzyme 2 (PC2) is essential for processing pro-islet amyloid polypeptide at the NH2-terminal cleavage site.
Jiayin Wang
,
J. Xu
,
John R. Finnerty
,
Mayuko Furuta
,
David Steiner
,
C Bruce Verchere
Diabetes
2001
Impaired processing of pro-islet amyloid polypeptide (proIAPP), the precursor of the beta-cell peptide islet amyloid polypeptide…Â
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2000
2000
Identification and characterization of proSAAS, a granin-like neuroendocrine peptide precursor that inhibits prohormone processing.
Lloyd D Fricker
,
Audra A McKinzie
,
+10 authors
Jo Anne Douglass
The Journal of neuroscience : the official…
2000
Five novel peptides were identified in the brains of mice lacking active carboxypeptidase E, a neuropeptide-processing enzyme…Â
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Highly Cited
1995
Highly Cited
1995
Differential processing of proglucagon by the subtilisin-like prohormone convertases PC2 and PC3 to generate either glucagon or glucagon-like peptide.
Yves Rouillé
,
Stephen J Martin
,
David Steiner
The Journal of biological chemistry
1995
Proglucagon is processed differently in the islet alpha cells and the intestinal endocrine L cells to release either glucagon or…Â
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1994
1994
Endoproteolytic processing of proopiomelanocortin and prohormone convertases 1 and 2 in neuroendocrine cells overexpressing prohormone convertases 1 or 2.
A. Zhou
,
Richard E Mains
The Journal of biological chemistry
1994
AtT-20 mouse corticotrope tumor cell lines overexpressing the prohormone convertases PC1 or PC2 were established and used to…Â
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1994
1994
7B2 is a neuroendocrine chaperone that transiently interacts with prohormone convertase PC2 in the secretory pathway.
J Anneke M Braks
,
G. J. Martens
Cell
1994
The neuroendocrine polypeptide 7B2 is a highly conserved secretory protein selectively present in prohormone-producing cells…Â
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1993
1993
Purification and characterization of the prohormone convertase PC1(PC3).
Y. Zhou
,
Inger Lindberg
The Journal of biological chemistry
1993
The prohormone convertases PC1 (also known as PC3) and PC2 have been implicated in the biosynthesis of several polypeptide…Â
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1991
1991
Cloning and primary sequence of a mouse candidate prohormone convertase PC1 homologous to PC2, Furin, and Kex2: distinct chromosomal localization and messenger RNA distribution in brain and pituitary…
Nabil G Seidah
,
Martin M. Marcinkiewicz
,
+6 authors
M. Chrétien
Molecular endocrinology
1991
Using a 796-basepair cDNA fragment obtained from a mouse pituitary library we have screened two mouse insulinoma libraries and…Â
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