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paired basic amino acid cleaving enzyme

Known as: Furin Preproprotein, SPC1 Proteinase, Paired Basic Amino Acid Residue-Cleaving Enzyme 
A proprotein convertase with specificity for the proproteins of PROALBUMIN; COMPLEMENT 3C; and VON WILLEBRAND FACTOR. It has specificity for cleavage… 
National Institutes of Health

Related topics

Related topics

19 relations
Enzyme GeneFURIN geneHydrolysisIn Blood

Broader (2)

Prohormone ConvertasesSerine Endopeptidases

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2018
2018
A Method to Produce and Purify Full-Length Recombinant Alpha Dystroglycan : Analysis of Nand O-Linked Monosaccharide Composition in CHO Cells with or without LARGE Overexpression
? dystroglycan (?DG) is part of the dystrophin-associated glycoprotein (DAG) complex, a series of cytoskeletal, transmembrane… 
2017
2017
Hepcidin: Discovery to Destiny
Iron plays an important role in many essential biochemical processes of living creatures, so tight regulation of iron metabolism… 
2015
2015
C‐Terminal Cleavage of Human Foxp3 at a Proprotein Convertase Motif Abrogates its Suppressive Function
Foxp3 plays a critical role in the development and function of regulatory T cells (Tregs). Differences in translational and post… 
Review
2012
Review
2012
[Structure and properties of proprotein convertase inhibitors].
This review is devoted to structure and properties of proprotein convertases (PCs), the intracellular Ca(2+)-dependent serine… 
2012
2012
Opposite Roles of Furin and PC 5 A in N-Cadherin Processing 1
We recently demonstrated that lack of Furin-processing of the N-cadherin precursor (proNCAD) in highly invasive melanoma and… 
2011
2011
Effects of short-term glucocorticoid treatment on changes in cartilage matrix degradation and chondrocyte gene expression induced by mechanical injury
Introduction: Traumatic joint injury damages cartilage and causes adjacent joint tissues to release inflammatory cytokines… 
2010
2010
[New non-peptide inhibitors of furin].
Furin, a human subtilisin-related proprotein convertase, is the most important pharmaceutical target because it plays a vital… 
Review
2001
Review
2001
Erratum: A furin-like convertase mediates propeptide cleavage of BACE, the Alzheimer's β-secretase (The Journal of Biological Chemistry (2002) 275 (37712-37717))
T HE J OURNAL OF B IOLOGICAL C HEMISTRY © 2000 by The American Society for Biochemistry and Molecular Biology, Inc. Vol. 275, No… 
2001
2001
Rational Redesign of Inhibitors of Furin/kexin Processing Proteases.
Furin/kexin processing proteases catalyze the proteolysis of large protein precursors involved in many biological processes, such… 
2000
2000
Nonhistone protein purified from porcine kidney acts as a suicide substrate inhibitor on furin-like enzyme.
AIM To search and purify a naturally occurring protein inhibitor of the furin-like enzyme from the porcine kidney. METHODS…