paired basic amino acid cleaving enzyme

Known as: Furin Preproprotein, SPC1 Proteinase, Paired Basic Amino Acid Residue-Cleaving Enzyme 
A proprotein convertase with specificity for the proproteins of PROALBUMIN; COMPLEMENT 3C; and VON WILLEBRAND FACTOR. It has specificity for cleavage… (More)
National Institutes of Health

Papers overview

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Highly Cited
2008
Highly Cited
2008
The liver peptide hepcidin regulates iron absorption and recycling. Hemojuvelin (HJV) has a key role in hepcidin regulation, and… (More)
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Highly Cited
2007
Highly Cited
2007
Matrix metalloproteinases (MMPs) disrupt the blood-brain barrier (BBB) during reperfusion. Occludin and claudins are recently… (More)
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Highly Cited
2007
Highly Cited
2007
Epithelial sodium channels (ENaC) are expressed in the apical membrane of high resistance Na(+) transporting epithelia and have a… (More)
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Highly Cited
2001
Highly Cited
2001
The tripartite toxin secreted by Bacillus anthracis, the causative agent of anthrax, helps the bacterium evade the immune system… (More)
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Review
1999
Review
1999
As part of a study to identify novel genes associated with macrophage activation, we have cloned a new member of the transforming… (More)
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Highly Cited
1998
Highly Cited
1998
The Notch receptor, which is involved in numerous cell fate decisions in invertebrates and vertebrates, is synthesized as a 300… (More)
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Highly Cited
1998
Highly Cited
1998
In the present study, we have investigated processing and maturation of the envelope glycoprotein (GP) of Ebola virus. When GP… (More)
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Highly Cited
1997
Highly Cited
1997
Flaviviruses are assembled intracellularly in an immature form containing heterodimers of two envelope proteins, E and prM… (More)
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Highly Cited
1996
Highly Cited
1996
Membrane type 1-matrix metalloproteinase (MT1-MMP) initiates the activation of the zymogen progelatinase A/ 72-kDa type IV… (More)
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Highly Cited
1992
Highly Cited
1992
Proteolytic cleavage of the protective antigen (PA) protein of anthrax toxin at residues 164-167 is necessary for toxic activity… (More)
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