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Proprotein Convertase 2

Known as: PC2 Protein, Endoprotease, PC2, Prohormone Convertase, PC2 
A serine endopeptidase that has specificity for cleavage at ARGININE. It cleaves a variety of prohormones including PRO-OPIOMELANOCORTIN… 
National Institutes of Health

Related topics

Related topics

11 relations
In BloodPCSK2 geneProcess of secretionantagonists & inhibitors

Broader (2)

Prohormone ConvertasesProprotein Convertases

Papers overview

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2010
2010
Nonlinear optical properties of phenoxy-phthalocyanines at 800 nm with femtosecond pulse excitation.
We investigated nonlinear optical properties of Phenoxy-phthalocyanine (Pc1) and Phenoxy-phthalocyanine-Zinc(II) (Pc2) at a… 
2010
2010
Diversity of methanogenic archaeal communities in Japanese paddy field ecosystem, estimated by denaturing gradient gel electrophoresis
Diversity of methanogenic archaeal communities in Japanese paddy field ecosystem was evaluated by the denaturing gradient gel… 
2007
2007
Developmental rates, structural asymmetry, and metabolic fingerprints of steelhead trout (Oncorhynchus mykiss) eggs incubated at two temperatures
Temperature stress on developing steelhead (Oncorhynchus mykiss) was evaluated using asymmetry of skeletal characters, fish… 
2002
2002
Functional Characterization of ProSAAS
Prohormone convertases (PC) 1 and 2, enzymes found primarily in neuroendocrine tissues, are thought to mediate the proteolytic… 
2002
2002
Variations in Quercus ilex chloroplast pigment content during summer stress: involvement in photoprotection according to principal component analysis.
We examined chloroplast pigment variation in holm oak (Quercus ilex L.) leaves for two periods under two climatic conditions, at… 
2000
2000
Quantitative Expression Analysis of Genes Regulated by Both Obesity and Leptin Reveals a Regulatory Loop between Leptin and Pituitary-derived ACTH*
Absence of the hormone leptin leads to dramatic increases in appetite, food intake, and adiposity. The primary site of action, at… 
1998
1998
Organization of the human carboxypeptidase E gene and molecular scanning for mutations in Japanese subjects with NIDDM or obesity
Summary Insulin is synthesized in the pancreatic beta cell as a larger precursor molecule proinsulin which is converted to… 
1995
1995
Association of the Prohormone Convertase 2 Gene (PCSK2) on Chromosome 20 with NIDDM in Japanese Subjects
Proinsulin is converted to insulin by the concerted action of two sequence-specific subtilisin-like proteases termed prohormone… 
1995
1995
Molecular Modeling of the Substrate Specificity of Prohormone Convertases SPC2 and SPC3 (*)
In this paper we describe the results of molecular modeling of the structures of the active sites of two subtilisin-like… 
1992
1992
Prohormone Thiol Protease and Enkephalin Precursor Processing: Cleavage at Dibasic and Monobasic Sites
Production of active enkephalin peptides requires proteolytic processing of proenkephalin at dibasic Lys‐Arg, Arg‐Arg, and Lys… 
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