Proprotein Convertase 2

Known as: PC2 Protein, Endoprotease, PC2, Prohormone Convertase, PC2 
A serine endopeptidase that has specificity for cleavage at ARGININE. It cleaves a variety of prohormones including PRO-OPIOMELANOCORTIN… (More)
National Institutes of Health

Papers overview

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Review
2013
Review
2013
The secretory proprotein convertase (PC) family comprises nine members: PC1/3, PC2, furin, PC4, PC5/6, PACE4, PC7, SKI-1/S1P, and… (More)
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Review
2011
Review
2011
The proprotein convertases (PCs) are secretory mammalian serine proteinases related to bacterial subtilisin-like enzymes. The… (More)
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Highly Cited
2011
Highly Cited
2011
Glycemic control is improved more after gastric bypass surgery (GBP) than after equivalent diet-induced weight loss in patients… (More)
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Review
2008
Review
2008
The mammalian secretory proprotein convertases are part of a family of nine serine proteinases of the subtilisin-type. Seven of… (More)
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Review
2003
Review
2003
The proprotein convertases (PCs) are a seven-member family of endoproteases that activate proproteins by cleavage at basic motifs… (More)
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Highly Cited
2003
Highly Cited
2003
Polycomb group (PcG) proteins form large multimeric complexes (PcG bodies) which are involved in the stable repression of gene… (More)
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Review
2002
Review
2002
Precursor proteins that transit through the secretory pathway often require processing at specific sites in order to release… (More)
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Highly Cited
2001
Highly Cited
2001
Mutations in polycystins-1 and -2 (PC1 and PC2) cause autosomal dominant polycystic kidney disease (ADPKD), which is… (More)
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Review
1998
Review
1998
The major endoproteolytic processing enzymes of the secretory pathway are the subtilisin-like proprotein convertases (SPCs… (More)
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Highly Cited
1992
Highly Cited
1992
Experiments using recombinant vaccinia viruses expressing rat proinsulin I coinfected into COS-7 cells with recombinant vaccinia… (More)
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