Proprotein Convertases

Known as: Convertase, Proprotein, Proprotein Convertase, Proprotein Convertases [Chemical/Ingredient] 
Proteolytic enzymes that are involved in the conversion of protein precursors such as peptide prohormones into PEPTIDE HORMONES. Some are… (More)
National Institutes of Health

Papers overview

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Review
2008
Review
2008
The mammalian secretory proprotein convertases are part of a family of nine serine proteinases of the subtilisin-type. Seven of… (More)
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Review
2005
Review
2005
The discovery of mammalian subtilases, proprotein convertases (PCs) or subtilisin-like proprotein convertases (SPCs), in 1990 was… (More)
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Highly Cited
2004
Highly Cited
2004
Many secretory proteins and peptides are synthesized as inactive precursors that in addition to signal peptide cleavage undergo… (More)
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Highly Cited
2004
Highly Cited
2004
OBJECTIVE Neural apoptosis-regulated convertase (NARC)-1 is the newest member of the proprotein convertase family implicated in… (More)
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Highly Cited
2003
Highly Cited
2003
Seven secretory mammalian kexin-like subtilases have been identified that cleave a variety of precursor proteins at monobasic and… (More)
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Review
2003
Review
2003
The proprotein convertases (PCs) are a seven-member family of endoproteases that activate proproteins by cleavage at basic motifs… (More)
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Highly Cited
2003
Highly Cited
2003
The secretory factor VEGF-C has been directly implicated in various physiological processes during embryogenesis and human… (More)
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Highly Cited
2000
Highly Cited
2000
Membrane type-1 matrix metalloproteinase (MT1-MMP) is the prototypical member of a subgroup of membrane-anchored proteinases that… (More)
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Highly Cited
1999
Highly Cited
1999
Bone morphogenetic proteins (BMPs) are derived from inactive precursor proteins by endoproteolytic cleavage. Here we show that… (More)
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Review
1998
Review
1998
The major endoproteolytic processing enzymes of the secretory pathway are the subtilisin-like proprotein convertases (SPCs… (More)
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