Proenkephalin-A, human

Known as: Preproenkephalin, Proenkephalin-A, Proenkephalin A 
Proenkephalin-A (267 aa, ~31 kDa) is encoded by the human PENK gene. This protein is involved in opioid receptor signaling.
National Institutes of Health

Topic mentions per year

Topic mentions per year

1982-2018
0102019822018

Papers overview

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Highly Cited
2010
Highly Cited
2010
Maternal obesity during pregnancy increases the risk of obesity in the offspring. Obesity, arising from an imbalance of energy… (More)
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Highly Cited
2005
Highly Cited
2005
Huntington's disease (HD) is a fatal neurodegenerative disorder caused by the presence of an abnormally expanded polyglutamine… (More)
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Highly Cited
2002
Highly Cited
2002
Several peptide fragments are produced by proteolytic cleavage of the opioid peptide precursor proenkephalin A, and among these… (More)
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Highly Cited
2002
Highly Cited
2002
Pancreatic intraductal neoplasia (PanIN) is thought to be the precursor to infiltrating pancreatic ductal adenocarcinoma. We have… (More)
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Highly Cited
1998
Highly Cited
1998
Rats sustaining unilateral near-complete 6-hydroxydopamine lesions of the mesostriatal dopamine pathway received daily injections… (More)
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Highly Cited
1998
Highly Cited
1998
In situ hybridization was combined with FluoroGold retrograde labelling to determine the distribution of messenger RNAs for the… (More)
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Highly Cited
1990
Highly Cited
1990
In situ hybridization experiments were performed with brain sections from normal, control and haloperidol-treated rats to… (More)
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Highly Cited
1988
Highly Cited
1988
Synthesis of the endogenous opioid precursor, proenkephalin, is regulated by neurotransmitters and membrane depolarization. These… (More)
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Highly Cited
1984
Highly Cited
1984
A cDNA-clone library was constructed from poly-adenylated RNA of Fischer rat striatum and screened for inserts coding for the… (More)
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Highly Cited
1982
Highly Cited
1982
The nucleotide sequence of cloned cDNA for preproenkephalin from bovine adrenal medulla indicates that the precursor protein… (More)
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