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Proenkephalin-A, human

Known as: Preproenkephalin, Proenkephalin-A, Proenkephalin A 
Proenkephalin-A (267 aa, ~31 kDa) is encoded by the human PENK gene. This protein is involved in opioid receptor signaling.
National Institutes of Health

Related topics

Related topics

8 relations
NeuronsNociceptionPENK geneReceptor Signaling

Broader (2)

preproenkephalin Aproenkephalin A

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2001
2001
Prenatal nicotine affects catecholamine gene expression in newborn rat carotid body and petrosal ganglion.
Nicotine exposure modifies the expression of catecholamine and opioid neurotransmitter systems involved in attenuation of hypoxic… 
Highly Cited
1997
Highly Cited
1997
Enkephalinergic and dynorphinergic neurons in the spinal cord and dorsal root ganglia of the polyarthritic rat — in vivo release and cDNA hybridization studies
Highly Cited
1995
Highly Cited
1995
Chronicl-DOPA treatment differentially regulates gene expression of glutamate decarboxylase, preproenkephalin and preprotachykinin in the striatum of 6-hydroxydopamine-lesioned rat
1992
1992
Posttranslational processing of proenkephalin in AtT-20 cells: evidence for cleavage at a Lys-Lys site.
Proteolytic processing of proenkephalin was examined in several subclones of AtT-20 cells stably transfected with rat… 
Highly Cited
1991
Highly Cited
1991
Purification and characterization of a novel thiol protease involved in processing the enkephalin precursor.
1989
1989
Induction of phenylethanolamine N-methyltransferase mRNA expression by glucocorticoids in cultured bovine adrenal chromaffin cells.
Highly Cited
1988
Highly Cited
1988
A common trans-acting factor is involved in transcriptional regulation of neurotransmitter genes by cyclic AMP
Activation of neurotransmitter receptors can regulate transcription in postsynaptic cells through the actions of second… 
Highly Cited
1986
Highly Cited
1986
Glucocorticoids and cyclic AMP synergistically regulate the abundance of preproenkephalin messenger RNA in neuroblastoma-glioma hybrid cells.
Highly Cited
1984
Highly Cited
1984
Effect of intranigral injections of dynorphin, dynorphin fragments and alpha-neoendorphin on rotational behaviour in the rat.
1982
1982
Proenkephalin: a general pathway for enkephalin biosynthesis in animal tissues.
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