Skip to search formSkip to main content
You are currently offline. Some features of the site may not work correctly.

Proenkephalin-A, human

Known as: Preproenkephalin, Proenkephalin-A, Proenkephalin A 
Proenkephalin-A (267 aa, ~31 kDa) is encoded by the human PENK gene. This protein is involved in opioid receptor signaling.
National Institutes of Health

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2010
Highly Cited
2010
Maternal obesity during pregnancy increases the risk of obesity in the offspring. Obesity, arising from an imbalance of energy… Expand
  • table 1
  • figure 2
  • figure 1
  • figure 3
  • figure 4
Is this relevant?
Review
2010
Review
2010
Non-human primate (NHP) models of Parkinson's disease (PD) have been essential in understanding the pathophysiology and neural… Expand
  • table 1
  • table 2
Is this relevant?
Highly Cited
2005
Highly Cited
2005
Huntington's disease (HD) is a fatal neurodegenerative disorder caused by the presence of an abnormally expanded polyglutamine… Expand
Is this relevant?
Highly Cited
2002
Highly Cited
2002
Several peptide fragments are produced by proteolytic cleavage of the opioid peptide precursor proenkephalin A, and among these… Expand
  • figure 1
  • figure 1
  • figure 2
  • figure 3
  • figure 4
Is this relevant?
Highly Cited
2002
Highly Cited
2002
Pancreatic intraductal neoplasia (PanIN) is thought to be the precursor to infiltrating pancreatic ductal adenocarcinoma. We have… Expand
Is this relevant?
Highly Cited
2002
Highly Cited
2002
Peptide F [preproenkephalin (107–140)] has been shown to have stress-induced opiate-like activities with both analgesic and… Expand
Is this relevant?
Highly Cited
1998
Highly Cited
1998
Rats sustaining unilateral near-complete 6-hydroxydopamine lesions of the mesostriatal dopamine pathway received daily injections… Expand
Is this relevant?
Highly Cited
1997
Highly Cited
1997
In situ hybridization was combined with FluoroGold retrograde labelling to determine the distribution of messenger RNAs for the… Expand
Is this relevant?
Review
1996
Review
1996
In the central nervous system (CNS), dopamine is involved in the control of locomotion, cognition, affect and neuroendocrine… Expand
Is this relevant?
Highly Cited
1982
Highly Cited
1982
The nucleotide sequence of cloned cDNA for preproenkephalin from bovine adrenal medulla indicates that the precursor protein… Expand
Is this relevant?