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PENK gene

Known as: PENK, preproenkephalin, PROENKEPHALIN 
This gene is involved in neuropeptide signaling.
National Institutes of Health

Related topics

Related topics

8 relations
Leu-EnkephalinMethionine EnkephalinNociceptionProenkephalin-A, human

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
1995
Highly Cited
1995
The kappa-opioid receptor is primarily postsynaptic: combined immunohistochemical localization of the receptor and endogenous opioids.
Antisera were raised against a synthetic peptide corresponding to the carboxyl terminus of the kappa-opioid receptor (KOR1… 
Review
1994
Review
1994
Proteases and the emerging role of protease inhibitors in prohormone processing
Peptide hormones and neurotransmitters constitute a large class of neurohumoral agents that mediate cell‐cell communication in… 
Highly Cited
1991
Highly Cited
1991
Identification of opioid peptides regulating proliferation of neurons and glia in the developing nervous system
Highly Cited
1991
Highly Cited
1991
cAMP-dependent regulation of proenkephalin by JunD and JunB: positive and negative effects of AP-1 proteins.
We demonstrate that JunD, a component of the AP-1 transcription factor complex, activates transcription of the human… 
Highly Cited
1988
Highly Cited
1988
A common trans-acting factor is involved in transcriptional regulation of neurotransmitter genes by cyclic AMP
Activation of neurotransmitter receptors can regulate transcription in postsynaptic cells through the actions of second… 
Highly Cited
1988
Highly Cited
1988
Dopaminergic regulation of striatal proenkephalin mrna and prodynorphin mrna: Contrasting effects of d1 and d2 antagonists
Highly Cited
1988
Highly Cited
1988
Expression of preproenkephalin mRNA by cultured astrocytes and neurons.
Expression of preproenkephalin mRNA by developing glia and neurons was examined in cultures of embryonic and neonatal rat brain… 
Highly Cited
1987
Highly Cited
1987
Differential regulation of neuropeptide and proto-oncogene mRNA content in the hippocampus following recurrent seizures.
Highly Cited
1984
Highly Cited
1984
Isolation and characterization of the rat proenkephalin gene.
The rat proenkephalin gene has been isolated by molecular cloning and characterized by DNA-sequence analysis. The gene exhibits a… 
Highly Cited
1982
Highly Cited
1982
Isolation and structural organization of the human preproenkephalin B gene
The primary structure of porcine preproenkephalin B has been elucidated by cloning and sequencing cDNA1: it contains… 
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