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Platelet-Derived Growth Factor

Known as: Growth Factor, Platelet-Derived, Platelet-Derived Growth Factor [Chemical/Ingredient], Platelet Derived Growth Factor 
A family of growth factors that act as potent mitogens and are involved in the stimulation of angiogenesis. There are four members of this family… 
National Institutes of Health

Related topics

Related topics

33 relations
BecaplerminCell ProliferationFIGF protein, humanGrowth Factor

Broader (3)

Blood ProteinsGrowth SubstancesPeptides

Narrower (4)

PDGFD protein, humanplatelet-derived growth factor Aplatelet-derived growth factor ABplatelet-derived growth factor C

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2004
Highly Cited
2004
Simultaneous Blockade of Platelet-Derived Growth Factor-Receptor and Epidermal Growth Factor-Receptor Signaling and Systemic Administration of Paclitaxel as Therapy for Human Prostate Cancer…
Once prostate cancer metastasizes to bone, conventional chemotherapy is largely ineffective. We hypothesized that inhibition of… 
Highly Cited
2001
Highly Cited
2001
PDGF-regulated rab4-dependent recycling of alphavbeta3 integrin from early endosomes is necessary for cell adhesion and spreading.
BACKGROUND It has been postulated that the regulation of integrin vesicular traffic facilitates cell migration by internalizing… 
Highly Cited
2000
Highly Cited
2000
Diagnostic potential of PhotoSELEX-evolved ssDNA aptamers.
Highly Cited
1994
Highly Cited
1994
Immunohistochemistry analysis of platelet-derived growth factor A and B chains and platelet-derived growth factor alpha and beta receptor expression in benign prostatic hyperplasias and Gleason…
The purpose of this study was to determine whether changes in the expression of platelet-derived growth factor (PDGF) and its… 
Highly Cited
1994
Highly Cited
1994
Stimulation of the platelet-derived growth factor beta receptor signaling pathway activates protein kinase C-delta
The murine myeloid progenitor cell line 32D was recently shown to undergo monocytic differentiation when protein kinase C-delta… 
Highly Cited
1993
Highly Cited
1993
Synergistic actions of platelet‐derived growth factor and the insulin‐like growth factors in vivo
Topical application of growth factors has been shown to benefit both normal and impaired wound healing. In normal tissue repair… 
Highly Cited
1989
Highly Cited
1989
Identification of a developmentally regulated protein-tyrosine kinase by using anti-phosphotyrosine antibodies to screen a cDNA expression library.
To identify the protein-tyrosine kinases that are expressed during chicken embryonic development, a 10-day chicken embryo cDNA… 
Highly Cited
1984
Highly Cited
1984
Simian sarcoma virus--transformed cells secrete a mitogen identical to platelet-derived growth factor.
Normal rat kidney (NRK) cells transformed by simian sarcoma virus (SSV) release into the culture medium a biologically active… 
Highly Cited
1981
Highly Cited
1981
Serotonin receptor-mediated stimulation of bovine smooth muscle cell prostacyclin synthesis and its modulation by platelet-derived growth factor.
Serotonin (5-hydroxytryptamine; 0.5 microM and above) stimulated the synthesis of prostacyclin (as measured by radioimmunoassay… 
Highly Cited
1978
Highly Cited
1978
Physiological quiescence in plasma‐derived serum: Influence of platelet‐derived growth factor on cell growth in culture
A platelet‐derived growth factor can be shown to be the principal stimulant of DNA synthesis in whole blood serum for those cells… 
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