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Platelet-Derived Growth Factor
Known as:
Growth Factor, Platelet-Derived
, Platelet-Derived Growth Factor [Chemical/Ingredient]
, Platelet Derived Growth Factor
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A family of growth factors that act as potent mitogens and are involved in the stimulation of angiogenesis. There are four members of this family…
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National Institutes of Health
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Related topics
Related topics
33 relations
Becaplermin
Cell Proliferation
FIGF protein, human
Growth Factor
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Broader (3)
Blood Proteins
Growth Substances
Peptides
Narrower (4)
PDGFD protein, human
platelet-derived growth factor A
platelet-derived growth factor AB
platelet-derived growth factor C
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2004
Highly Cited
2004
Simultaneous Blockade of Platelet-Derived Growth Factor-Receptor and Epidermal Growth Factor-Receptor Signaling and Systemic Administration of Paclitaxel as Therapy for Human Prostate Cancer…
S. J. Kim
,
H. Uehara
,
+6 authors
I. Fidler
Cancer Research
2004
Corpus ID: 9967094
Once prostate cancer metastasizes to bone, conventional chemotherapy is largely ineffective. We hypothesized that inhibition of…
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Highly Cited
2001
Highly Cited
2001
PDGF-regulated rab4-dependent recycling of alphavbeta3 integrin from early endosomes is necessary for cell adhesion and spreading.
M. Roberts
,
S. Barry
,
A. Woods
,
P. van der Sluijs
,
J. Norman
Current Biology
2001
Corpus ID: 12805404
BACKGROUND It has been postulated that the regulation of integrin vesicular traffic facilitates cell migration by internalizing…
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Highly Cited
2000
Highly Cited
2000
Diagnostic potential of PhotoSELEX-evolved ssDNA aptamers.
M. C. Golden
,
B. Collins
,
M. Willis
,
T. Koch
Journal of Biotechnology
2000
Corpus ID: 28247735
Highly Cited
1994
Highly Cited
1994
Immunohistochemistry analysis of platelet-derived growth factor A and B chains and platelet-derived growth factor alpha and beta receptor expression in benign prostatic hyperplasias and Gleason…
K. Fudge
,
Wang Cy
,
Stearns Me
Modern Pathology
1994
Corpus ID: 10628676
The purpose of this study was to determine whether changes in the expression of platelet-derived growth factor (PDGF) and its…
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Highly Cited
1994
Highly Cited
1994
Stimulation of the platelet-derived growth factor beta receptor signaling pathway activates protein kinase C-delta
W. Li
,
J. Yu
,
+4 authors
J. Pierce
Molecular and Cellular Biology
1994
Corpus ID: 32099796
The murine myeloid progenitor cell line 32D was recently shown to undergo monocytic differentiation when protein kinase C-delta…
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Highly Cited
1993
Highly Cited
1993
Synergistic actions of platelet‐derived growth factor and the insulin‐like growth factors in vivo
D. Greenhalgh
,
R. Hummel
,
Steven Albertson
,
M. Breeden
Wound Repair and Regeneration
1993
Corpus ID: 23489206
Topical application of growth factors has been shown to benefit both normal and impaired wound healing. In normal tissue repair…
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Highly Cited
1989
Highly Cited
1989
Identification of a developmentally regulated protein-tyrosine kinase by using anti-phosphotyrosine antibodies to screen a cDNA expression library.
Elena B. Pasquale
,
S. Singer
Proceedings of the National Academy of Sciences…
1989
Corpus ID: 9302063
To identify the protein-tyrosine kinases that are expressed during chicken embryonic development, a 10-day chicken embryo cDNA…
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Highly Cited
1984
Highly Cited
1984
Simian sarcoma virus--transformed cells secrete a mitogen identical to platelet-derived growth factor.
A. Owen
,
P. Pantazis
,
H. Antoniades
Science
1984
Corpus ID: 2322356
Normal rat kidney (NRK) cells transformed by simian sarcoma virus (SSV) release into the culture medium a biologically active…
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Highly Cited
1981
Highly Cited
1981
Serotonin receptor-mediated stimulation of bovine smooth muscle cell prostacyclin synthesis and its modulation by platelet-derived growth factor.
S. Coughlin
,
M. Moskowitz
,
H. Antoniades
,
L. Levine
Proceedings of the National Academy of Sciences…
1981
Corpus ID: 19280620
Serotonin (5-hydroxytryptamine; 0.5 microM and above) stimulated the synthesis of prostacyclin (as measured by radioimmunoassay…
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Highly Cited
1978
Highly Cited
1978
Physiological quiescence in plasma‐derived serum: Influence of platelet‐derived growth factor on cell growth in culture
R. Ross
,
C. Nist
,
B. Kariya
,
M. Rivest
,
E. Raines
,
Jim Callis
Journal of Cellular Physiology
1978
Corpus ID: 13470272
A platelet‐derived growth factor can be shown to be the principal stimulant of DNA synthesis in whole blood serum for those cells…
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