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Cutaneous Wound Healing
Overall, burns are smaller than 20 years ago, but even small burns can leave patients with debilitating scars. The management of the burn wound and resultant scarring requires the integration ofExpand
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PDGF and FGF stimulate wound healing in the genetically diabetic mouse.
To examine the effects of recombinant growth factors in vivo, impaired wound healing was studied in genetically diabetic C57BL/KsJ-db/db mice. Large full-thickness skin wounds made on the backs ofExpand
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Regulation of Vascular Endothelial Growth Factor Expression in Cultured Keratinocytes.
Recent in situ hybridization studies had demonstrated a strong increase in vascular endothelial growth factor (VEGF) mRNA expression in the hyperproliferative epithelium during wound healing. ToExpand
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American Burn Association Consensus Conference to Define Sepsis and Infection in Burns
Because of their extensive wounds, burn patients are chronically exposed to inflammatory mediators. Thus, burn patients, by definition, already have “systemic inflammatory response syndrome.” CurrentExpand
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The role of apoptosis in wound healing.
  • D. Greenhalgh
  • Biology, Medicine
  • The international journal of biochemistry & cell…
  • 1 September 1998
Wound healing involves a series of rapid increases in specific cell populations that prepare the wound for repair, deposit new matrices and finally, mature the wound. Upon completing their tasks,Expand
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A multicenter review of toxic epidermal necrolysis treated in U.S. burn centers at the end of the twentieth century.
: Toxic epidermal necrolysis (TEN) is a potentially fatal disorder that involves large areas of skin desquamation. Patients with TEN are often referred to burn centers for expert wound management andExpand
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Release of abdominal compartment syndrome improves survival in patients with burn injury.
BACKGROUND Abdominal compartment syndrome (ACS) has rarely been described as a complication of burn injury. This study describes cases of ACS in patients with burn injury and the physiologic resultsExpand
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Predisposing factors for self-inflicted burns.
Self-inflicted burn injuries, although uncommon, are a significant source of morbidity and mortality. The purpose of this study was to delineate the characteristics of these burns and to examineExpand
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A multicenter review of toxic epidermal necrolysis treated in U.S. burn centers at the end of the twentieth century.
Toxic epidermal necrolysis (TEN) is a potentially fatal disorder that involves large areas of skin desquamation. Patients with TEN are often referred to burn centers for expert wound management andExpand
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Targeted epidermal expression of mutant Connexin 26(D66H) mimics true Vohwinkel syndrome and provides a model for the pathogenesis of dominant connexin disorders.
To investigate the role of connexins in dominantly inherited skin disease, transgenic mice were produced which expressed mutant connexin 26 [gjb2/connexin 26(D66H)], from a keratin 10 promoter,Expand
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