Cutaneous Wound Healing
The state of knowledge regarding wound healing is described, both what is known and what is not known, and to recap the priorities set by the breakout sessions of the Burn State of the Science: Research meeting.
American Burn Association Consensus Conference to Define Sepsis and Infection in Burns
- D. Greenhalgh, J. Saffle, B. Latenser
- MedicineJournal of burn care & research : official…
- 1 November 2007
The goal of the consensus conference was to develop and publish standardized definitions for sepsis and infection-related diagnoses in the burn population, which will improve the capability of performing more meaningful multicenter trials among burn centers.
PDGF and FGF stimulate wound healing in the genetically diabetic mouse.
- D. Greenhalgh, K. Sprugel, M. Murray, R. Ross
- Biology, MedicineAmerican Journal of Pathology
- 1 June 1990
The effectiveness of rPDGF-BB and rbFGF suggest that recombinant growth factors may be useful in the treatment of patients with deficient wound repair, and all parameters of healing but not to a greater extent than either growth factor alone.
Regulation of Vascular Endothelial Growth Factor Expression in Cultured Keratinocytes.
- S. Frank, Griseldis Hübner, G. Breier, M. Longaker, D. Greenhalgh, S. Werner
- Biology, MedicineJournal of Biological Chemistry
- 26 May 1995
In normal mice, elevated VEGF mRNA levels during the period when granulation tissue formation occurs are found, suggesting that a defect in V EGF regulation might be associated with wound healing disorders.
The role of apoptosis in wound healing.
- D. Greenhalgh
- Biology, MedicineInternational Journal of Biochemistry and Cell…
- 1 September 1998
A multicenter review of toxic epidermal necrolysis treated in U.S. burn centers at the end of the twentieth century.
Age, body surface area involvement, APACHE II score, complications, and parenteral nutrition before transfer correlated with increased mortality and early transport to a burn unit is warranted to improve patient outcome.
Release of abdominal compartment syndrome improves survival in patients with burn injury.
- Kristina G. Hobson, Kassie M. Young, A. Ciraulo, T. Palmieri, D. Greenhalgh
- MedicineThe Journal of trauma
- 1 December 2002
It is recommended to recommend bladder pressure monitoring for all patients with severe burn injuries and abdominal decompression in any patient who develops pressures greater than 30 mm Hg if they have signs of physiologic compromise.
Predisposing factors for self-inflicted burns.
- T. Pham, J. R. King, T. Palmieri, D. Greenhalgh
- Medicine, PsychologyJournal of Burn Care and Rehabilitation
- 1 July 2003
In addition to well-described psychiatric factors, common characteristics predisposing to self-inflicted burns include chronic medical illnesses, long-term disability, and a lack of access to adequate mental health care.
An assessment of acute kidney injury with modified RIFLE criteria in pediatric patients with severe burns
A high incidence of AKI is observed in the burn PICU population and Sepsis seems to contribute to the development of the Failure class ofAKI.
The importance of intra-abdominal pressure measurements in burned children.
Elevation of intra-abdominal pressure should be considered in severely burned patients with oliguria, hypoventilation, or hypotension in addition to standard care in patients with extensive burns.