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Plasminogen Activator

Known as: Plasminogen Activators, Plasminogen Activators [Chemical/Ingredient], activator plasminogen 
A heterogeneous group of proteolytic enzymes that convert PLASMINOGEN to FIBRINOLYSIN. They are concentrated in the lysosomes of most cells and in… 
National Institutes of Health

Related topics

Related topics

31 relations

Narrower (11)

ActilyseEminaseK1K2PuPla protease, Yersinia pestis

Broader (4)

EndopeptidasesFibrinolytic AgentsSerine EndopeptidasesSerine Proteases
Endothelial CellsEnzyme GeneHydrolysisIn Blood

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2010
Highly Cited
2010
Secretion of extracellular hsp90α via exosomes increases cancer cell motility: a role for plasminogen activation
BackgroundMetastasis is a multi-step process that is responsible for the majority of deaths in cancer patients. Current… 
Review
2001
Review
2001
Bacterial plasminogen activators and receptors.
Invasive bacterial pathogens intervene at various stages and by various mechanisms with the mammalian plasminogen/plasmin system… 
Highly Cited
1995
Highly Cited
1995
Plasminogen deficiency causes severe thrombosis but is compatible with development and reproduction.
Plasminogen (Plg)-deficient mice were generated to define the physiological roles of this key fibrinolytic protein and its… 
Highly Cited
1994
Highly Cited
1994
Physiological consequences of loss of plasminogen activator gene function in mice
Indirect evidence suggests a crucial role for the fibrinolytic system and its physiological triggers, tissue-type (t-PA) and… 
Highly Cited
1987
Highly Cited
1987
High and low affinity binding sites for basic fibroblast growth factor on cultured cells: Absence of a role for low affinity binding in the stimulation of plasminogen activator production by bovine…
Scatchard analysis of binding of 125l‐basic fibroblast growth factor (FGF) to baby hamster kidney (BHK) cells revealed the… 
Highly Cited
1986
Highly Cited
1986
Tumor invasion through the human amniotic membrane: Requirement for a proteinase cascade
Highly Cited
1985
Highly Cited
1985
Differentiation-enhanced binding of the amino-terminal fragment of human urokinase plasminogen activator to a specific receptor on U937 monocytes.
The purified amino-terminal fragment (ATF) of human urokinase plasminogen activator (residues 1-135), which is not required for… 
Highly Cited
1980
Highly Cited
1980
Hormonal induction of differentiation in teratocarcinoma stem cells: Generation of parietal endoderm by retinoic acid and dibutyryl cAMP
Highly Cited
1977
Highly Cited
1977
Endogenous activation of latent collagenase by rheumatoid synovial cells. Evidence for a role of plasminogen activator.
To elucidate the mechanism of synovial damage in rheumatoid arthritis, we studied the activation of latent collagenases released… 
Highly Cited
1974
Highly Cited
1974
SECRETION OF PLASMINOGEN ACTIVATOR BY STIMULATED MACROPHAGES
Cultured thioglycollate-stimulated peritoneal macrophages synthesize, accumulate, and continuously release high levels of… 
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