Phosphodiesterase 5 inhibitor

Known as: Phosphodiesterase V Inhibitor, Inhibitors, PDE5, PDE 5 Inhibitors 
Compounds that specifically inhibit PHOSPHODIESTERASE 5.
National Institutes of Health

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2009
Highly Cited
2009
Memory loss, synaptic dysfunction, and accumulation of amyloid beta-peptides (A beta) are major hallmarks of Alzheimer's disease… (More)
Is this relevant?
2009
2009
OBJECTIVE Following a report of sudden hearing loss in a patient taking phosphodiesterase type 5 inhibitor, and a Food and Drug… (More)
  • figure 1
  • figure 2
  • table I
  • table II
Is this relevant?
Highly Cited
2008
Highly Cited
2008
The pulmonary vascular bed is both a source of and target for a number of vasoactive factors. Among the most important for… (More)
  • figure 1
  • table 1
  • table 3
  • table 4
Is this relevant?
2007
2007
cGMP-degrading pathways have received little attention in the context of angiogenesis. In the present study we set out to… (More)
Is this relevant?
2007
2007
BACKGROUND Chronic prostatitis is a common urological complaint without clearly defined causation or definitive treatment… (More)
Is this relevant?
2006
2006
  • David Kleynberg
  • 2006
Volume 21, Issue 11, August 2006 1 the initial manifestation of underlying vascular disease. Regardless of the etiology… (More)
  • table 1
  • table 2
  • table 3
  • table 2
Is this relevant?
Highly Cited
2006
Highly Cited
2006
There are no published controlled clinical trials of regular phosphodiesterase type 5 inhibitor therapy as a long-term treatment… (More)
  • table 1
  • table 2
  • table 3
  • table 3
Is this relevant?
Highly Cited
2004
Highly Cited
2004
Sildenafil, a phosphodiesterase 5 inhibitor, is currently under investigation for therapy of pulmonary hypertension. This study… (More)
  • table 1
  • figure 1
  • figure 2
  • figure 3
  • figure 4
Is this relevant?
Highly Cited
2003
Highly Cited
2003
BACKGROUND Phosphodiesterase type 5 (PDE5) is a novel therapeutic target for the treatment of pulmonary hypertension. This study… (More)
  • figure 1
  • figure 2
  • figure 3
  • figure 4
  • figure 5
Is this relevant?
Review
1999
Review
1999
Investigations of recent years revealed that isozymes of cyclic-3', 5'-nucleotide phosphodiesterase (PDE) are a critically… (More)
Is this relevant?