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Sildenafil citrate
Known as:
1-((3-(6,7-Dihydro-1-methyl-7-oxo-3-propyl-1H-pyrazolo(4,3-d)pyrimidin-5-yl)-4-ethoxyphenyl)sulfonyl)-4-methylpiperazine citrate
, Citrate, Sildenafil
, Sildenafil Citrate [Chemical/Ingredient]
The citrate salt of a pyrazolopyrimidinone derivative structurally related to zaprinast. Sildenafil selectively inhibits cyclic guanosine…
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National Institutes of Health
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Related topics
Related topics
34 relations
12.5 ML sildenafil 0.8 MG/ML Injection
Acetildenafil
Desmethyl Sildenafil
Drug Allergy
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Narrower (5)
Homosildenafil
NCX-911
Revatio
UK 92480-10
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Broader (4)
Phosphodiesterase 5 inhibitor
Urological Agents
Vasodilator Agents
sildenafil
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2012
Highly Cited
2012
A Randomized, Double-Blind, Placebo-Controlled, Dose-Ranging Study of Oral Sildenafil Citrate in Treatment-Naive Children With Pulmonary Arterial Hypertension
R. Barst
,
D. Ivy
,
+8 authors
D. Wessel
Circulation
2012
Corpus ID: 231248
Background— Safe, effective therapy is needed for pediatric pulmonary arterial hypertension. Methods and Results— Children (n=235…
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Review
2008
Review
2008
Randomized, double-blind, placebo-controlled study of postoperative nightly sildenafil citrate for the prevention of erectile dysfunction after bilateral nerve-sparing radical prostatectomy
H. Padma-nathan
,
A. McCullough
,
+5 authors
G. Brock
International Journal of Impotence Research
2008
Corpus ID: 2514174
Four weeks after bilateral nerve-sparing radical retropubic prostatectomy, men with normal erectile function before surgery were…
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Highly Cited
2005
Highly Cited
2005
Sildenafil citrate therapy for pulmonary arterial hypertension.
N. Galiè
,
H. Ghofrani
,
+10 authors
G. Simonneau
The New England journal of medicine
2005
Corpus ID: 8614347
BACKGROUND Sildenafil inhibits phosphodiesterase type 5, an enzyme that metabolizes cyclic guanosine monophosphate, thereby…
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Highly Cited
2002
Highly Cited
2002
Sildenafil (Viagra) induces powerful cardioprotective effect via opening of mitochondrial K(ATP) channels in rabbits.
R. Ockaili
,
F. Salloum
,
J. Hawkins
,
R. Kukreja
American journal of physiology. Heart and…
2002
Corpus ID: 14787150
Sildenafil citrate (Viagra) is the pharmacological agent used to treat erectile dysfunction in men. Because this drug has a…
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Highly Cited
2002
Highly Cited
2002
Pharmacokinetics of sildenafil after single oral doses in healthy male subjects: absolute bioavailability, food effects and dose proportionality.
D. Nichols
,
G. Muirhead
,
J. Harness
British journal of clinical pharmacology
2002
Corpus ID: 26277023
AIMS To determine the absolute bioavailability, dose proportionality and the effects of food on the pharmacokinetics of single…
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Highly Cited
2002
Highly Cited
2002
Efficacy and safety of sildenafil citrate in women with sexual dysfunction associated with female sexual arousal disorder.
R. Basson
,
Rosemary McInnes
,
Mike D. Smith
,
Gemma Hodgson
,
N. Koppiker
Journal of women's health & gender-based medicine
2002
Corpus ID: 9809359
OBJECTIVE Sildenafil citrate (Viagra Pfizer, New York, NY) is indicated for the treatment of erectile dysfunction in men. The…
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Highly Cited
1999
Highly Cited
1999
Sildenafil for treatment of erectile dysfunction in men with diabetes: a randomized controlled trial. Sildenafil Diabetes Study Group.
M. Rendell
,
J. Rajfer
,
P. Wicker
,
M. Smith
JAMA
1999
Corpus ID: 43662200
CONTEXT Erectile dysfunction is common in men with diabetes. OBJECTIVE To assess the efficacy and safety of oral sildenafil…
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Highly Cited
1999
Highly Cited
1999
Diagnostic evaluation of the erectile function domain of the International Index of Erectile Function.
J. Cappelleri
,
R. Rosen
,
M. Smith
,
A. Mishra
,
I. Osterloh
Urology
1999
Corpus ID: 6739965
Highly Cited
1999
Highly Cited
1999
Effects of sildenafil citrate on human hemodynamics.
G. Jackson
,
N. Benjamin
,
N. Jackson
,
M. J. Allen
The American journal of cardiology
1999
Corpus ID: 35258718
Highly Cited
1998
Highly Cited
1998
Clinical safety of oral sildenafil citrate (VIAGRATM) in the treatment of erectile dysfunction
A. Morales
,
C. Gingell
,
M. Collins
,
P. Wicker
,
I. Osterloh
International Journal of Impotence Research
1998
Corpus ID: 23628347
Sildenafil citrate has been shown to be effective in a wide range of patients with erectile dysfunction and has been approved in…
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