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Sildenafil citrate

Known as: 1-((3-(6,7-Dihydro-1-methyl-7-oxo-3-propyl-1H-pyrazolo(4,3-d)pyrimidin-5-yl)-4-ethoxyphenyl)sulfonyl)-4-methylpiperazine citrate, Citrate, Sildenafil, Sildenafil Citrate [Chemical/Ingredient] 
The citrate salt of a pyrazolopyrimidinone derivative structurally related to zaprinast. Sildenafil selectively inhibits cyclic guanosine… Expand
National Institutes of Health

Papers overview

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Highly Cited
2007
Highly Cited
2007
PURPOSE We evaluated sildenafil for erectile dysfunction and lower urinary tract symptoms in men with the 2 conditions… Expand
Highly Cited
2006
Highly Cited
2005
Highly Cited
2005
BACKGROUND Sildenafil inhibits phosphodiesterase type 5, an enzyme that metabolizes cyclic guanosine monophosphate, thereby… Expand
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Highly Cited
2002
Highly Cited
2002
OBJECTIVE Sildenafil citrate (Viagra Pfizer, New York, NY) is indicated for the treatment of erectile dysfunction in men. The… Expand
Highly Cited
1999
Highly Cited
1999
CONTEXT Erectile dysfunction is common in men with diabetes. OBJECTIVE To assess the efficacy and safety of oral sildenafil… Expand
Review
1999
Review
1999
The pharmaceutical preparation sildenafil citrate (Viagra) is being widely prescribed as a treatment for male erectile… Expand
Highly Cited
1999
Highly Cited
1999
Sildenafil, a selective inhibitor of cyclic guanosine monophosphate (cGMP)-specific phosphodiesterase type 5 (PDE5), is a well… Expand
Highly Cited
1999
Highly Cited
1999
Nitric oxide (NO) induces the formation of intracellular cyclic guanosine monophosphate (cGMP) by guanylate cyclase. Sildenafil… Expand
Review
1999
Review
1999
Sildenafil, a selective inhibitor of phosphodiesterase type 5 (PDE5), is the first in a new class of orally effective treatments… Expand
Highly Cited
1998
Highly Cited
1998
Sildenafil citrate has been shown to be effective in a wide range of patients with erectile dysfunction and has been approved in… Expand
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