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Sildenafil citrate

Known as: 1-((3-(6,7-Dihydro-1-methyl-7-oxo-3-propyl-1H-pyrazolo(4,3-d)pyrimidin-5-yl)-4-ethoxyphenyl)sulfonyl)-4-methylpiperazine citrate, Citrate, Sildenafil, Sildenafil Citrate [Chemical/Ingredient] 
The citrate salt of a pyrazolopyrimidinone derivative structurally related to zaprinast. Sildenafil selectively inhibits cyclic guanosine… Expand
National Institutes of Health

Related topics

Related topics

34 relations
12.5 ML sildenafil 0.8 MG/ML InjectionAcetildenafilDesmethyl SildenafilDrug Allergy
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Narrower (5)

HomosildenafilNCX-911RevatioUK 92480-10
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Broader (4)

Phosphodiesterase 5 inhibitorUrological AgentsVasodilator Agentssildenafil

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2007
Highly Cited
2007
Sildenafil citrate improves erectile function and urinary symptoms in men with erectile dysfunction and lower urinary tract symptoms associated with benign prostatic hyperplasia: a randomized, double…
PURPOSE We evaluated sildenafil for erectile dysfunction and lower urinary tract symptoms in men with the 2 conditions… Expand
Highly Cited
2006
Highly Cited
2006
Sildenafil Citrate Therapy for Pulmonary Arterial Hypertension
 
Highly Cited
2005
Highly Cited
2005
Sildenafil citrate therapy for pulmonary arterial hypertension.
BACKGROUND Sildenafil inhibits phosphodiesterase type 5, an enzyme that metabolizes cyclic guanosine monophosphate, thereby… Expand
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Highly Cited
2002
Highly Cited
2002
Efficacy and safety of sildenafil citrate in women with sexual dysfunction associated with female sexual arousal disorder.
OBJECTIVE Sildenafil citrate (Viagra Pfizer, New York, NY) is indicated for the treatment of erectile dysfunction in men. The… Expand
Highly Cited
1999
Highly Cited
1999
Sildenafil for treatment of erectile dysfunction in men with diabetes: a randomized controlled trial. Sildenafil Diabetes Study Group.
CONTEXT Erectile dysfunction is common in men with diabetes. OBJECTIVE To assess the efficacy and safety of oral sildenafil… Expand
Review
1999
Review
1999
Use of sildenafil (Viagra) in patients with cardiovascular disease. Technology and Practice Executive Committee.
The pharmaceutical preparation sildenafil citrate (Viagra) is being widely prescribed as a treatment for male erectile… Expand
Highly Cited
1999
Highly Cited
1999
Sildenafil citrate and blood-pressure-lowering drugs: results of drug interaction studies with an organic nitrate and a calcium antagonist.
Sildenafil, a selective inhibitor of cyclic guanosine monophosphate (cGMP)-specific phosphodiesterase type 5 (PDE5), is a well… Expand
Highly Cited
1999
Highly Cited
1999
Effects of sildenafil citrate on human hemodynamics.
Nitric oxide (NO) induces the formation of intracellular cyclic guanosine monophosphate (cGMP) by guanylate cyclase. Sildenafil… Expand
Review
1999
Review
1999
Overall cardiovascular profile of sildenafil citrate.
Sildenafil, a selective inhibitor of phosphodiesterase type 5 (PDE5), is the first in a new class of orally effective treatments… Expand
Highly Cited
1998
Highly Cited
1998
Clinical safety of oral sildenafil citrate (VIAGRATM) in the treatment of erectile dysfunction
Sildenafil citrate has been shown to be effective in a wide range of patients with erectile dysfunction and has been approved in… Expand
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