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Aortic pulse wave velocity improves cardiovascular event prediction: an individual participant meta-analysis of prospective observational data from 17,635 subjects.
OBJECTIVES The goal of this study was to determine whether aortic pulse wave velocity (aPWV) improves prediction of cardiovascular disease (CVD) events beyond conventional risk factors. BACKGROUNDExpand
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The influence of heart rate on augmentation index and central arterial pressure in humans
1 Arterial stiffness is an important determinant of cardiovascular risk. Augmentation index (AIx) is a measure of systemic arterial stiffness derived from the ascending aortic pressure waveform. TheExpand
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The Deacon Cell and the other meridional cells of the Southern ocean
Abstract The meridional circulation cells of the Southern Ocean are investigated using the results from a fine-resolution primitive equation model. Zonal integration along depth levels shows theExpand
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Noninvasive assessment of arterial stiffness and risk of atherosclerotic events.
  • J. Oliver, D. Webb
  • Medicine
  • Arteriosclerosis, thrombosis, and vascular…
  • 1 April 2003
Investigation of arterial stiffness, especially of the large arteries, has gathered pace in recent years with the development of readily available noninvasive assessment techniques. These include theExpand
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Reproducibility of pulse wave velocity and augmentation index measured by pulse wave analysis
Objective The aim of this study was to determine the reproducibility of pulse wave velocity (PWV) and augmentation index (AIx) measured using pulse wave analysis (PWA), prior to its use inExpand
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Pulse transit time measured from the ECG: an unreliable marker of beat-to-beat blood pressure.
The arterial pulse-wave transit time can be measured between the ECG R-wave and the finger pulse (rPTT), and has been shown previously to have a linear correlation with blood pressure (BP). WeExpand
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Endothelin as a regulator of cardiovascular function in health and disease
The endothelins are a family of endothelium-derived peptides that possess characteristically sustained vasoconstrictor properties. Endothelin-1 appears to be the predominant member of the familyExpand
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Oxidized Phospholipid Inhibition of Toll-like Receptor (TLR) Signaling Is Restricted to TLR2 and TLR4
The generation of reactive oxygen species is a central feature of inflammation that results in the oxidation of host phospholipids. Oxidized phospholipids, such asExpand
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Circulating microRNAs as potential markers of human drug‐induced liver injury
New biomarkers of liver injury are required in the clinic and in preclinical pharmaceutical evaluation. Previous studies demonstrate that two liver‐enriched microRNAs (miR‐122 and miR‐192) areExpand
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Endothelial function and dysfunction. Part I: Methodological issues for assessment in the different vascular beds: a statement by the Working Group on Endothelin and Endothelial Factors of the
An enormous number of studies in the last two decades have been devoted to investigating the role of the endothelium in cardiovascular diseases. Nonetheless, the optimal methodology for investigatingExpand
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