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udenafil

Known as: 3-(1-methyl-7-oxo-3-propyl-4,7-dihydro-1H-pyrazolo[4,3-d]pyrimidin-5-yl)-N-{2-[(2RS)-1-methylpyrrolidin-2-yl]ethyl}-4-propoxybenzenesulfonamide, 5-(2-propyloxy-5-(1-methyl-2-pyrollidinylethylamidosulfonyl)phenyl)-1-methyl-3-propyl-1,6-dihydro-7H-pyrazolo (4,3-d) pyrimidine-7-one, Benzenesulfonamide, 3-(6,7-dihydro-1-methyl-7-oxo-3-propyl-1H-pyrazolo[4,3-d]pyrimidin-5-yl)-N-[2-(1-methyl-2-pyrrolidinyl)ethyl]-4-propoxy- 
A benzenesulfonamide derivative with vasodilatory activity. Udenafil selectively inhibits phosphodiesterase type 5 (PDE5), thus inhibiting the… 
National Institutes of Health

Related topics

Related topics

5 relations

Narrower (2)

DA-8159Zydena

Broader (3)

Phosphodiesterase 5 inhibitorPyrimidinesSulfonamides

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Review
2015
Review
2015
Phosphodiesterase 5 inhibitors for the treatment of erectile dysfunction: a trade-off network meta-analysis.
Highly Cited
2015
Highly Cited
2015
Synthesis and biological evaluation of pyrazolo-triazole hybrids as cytotoxic and apoptosis inducing agents.
A series of pyrazolo-triazole hybrids were designed and synthesized by combining the 1,3-diphenyl pyrazole and triazole scaffolds… 
Highly Cited
2004
Highly Cited
2004
Synthesis of 4,5-diaryl-1H-pyrazole-3-ol derivatives as potential COX-2 inhibitors.
4,5-Diaryl-1H-pyrazole-3-ol was utilized as a versatile template to synthesize several classes of compounds such as pyrazolo… 
Highly Cited
2004
Highly Cited
2004
Synthesis of some new annulated pyrazolo-pyrido (or pyrano) pyrimidine, pyrazolopyridine and pyranopyrazole derivatives.
The bifunctional pyrazolopyridine (2) and pyrano-pyrazole (3) derivatives were prepared by the reaction of 2-(2,4-dinitrophenyl… 
Highly Cited
2002
Highly Cited
2002
1H and 13C NMR Study of 1-Hydrazino-2,3-dihydro-1H-pyrazolo[1,2-a]pyridazine-5,8-diones and -1H-pyrazolo[1,2-b]phthalazine-5,10-diones and Their Ring-Chain Tautomerism
Treatment of 1-hydroxy-2,3-dihydro-1H-pyrazolo[1,2-a]pyridazine-5,8-diones and -1H-pyrazolo[1,2-b]phthalazine-5,10-diones with… 
Highly Cited
2000
Highly Cited
2000
[(3)H]MRE 3008F20: a novel antagonist radioligand for the pharmacological and biochemical characterization of human A(3) adenosine receptors.
The lack of a radiolabeled selective A(3) adenosine receptor antagonist is a major drawback for an adequate characterization of… 
Highly Cited
2000
Highly Cited
2000
Pyrazolo-triazoles as light activable DNA cleaving agents.
Review
1998
Review
1998
Safety and efficacy of sildenafil citrate in the treatment of male erectile dysfunction.
Highly Cited
1996
Highly Cited
1996
Effects of cyclic GMP elevation on isoprenaline‐induced increase in cyclic AMP and relaxation in rat aortic smooth muscle: role of phosphodiesterase 3
1 In rat aortic rings precontracted with phenylephrine, the β‐adrenoceptor agonist isoprenaline (10 nM to 30 μm) produces greater… 
1994
1994
Synthesis and analgesic properties of 5-acyl-arylhydrazone 1-H pyrazolo [3,4-b] pyridine derivatives.
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