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Pyrimidines

Known as: PYRIMIDINE, Pyrimidines [Chemical/Ingredient] 
One of two chemical compounds that cells use to make the building blocks of DNA and RNA. Examples of pyrimidines are cytosine, thymine, and uracil… 
National Institutes of Health

Related topics

Related topics

50 relations

Narrower (49)

1,4-dihydropyrimidine2-methyl-5,6-cyclopentapyrimidine4-(pyridin-2-yl)pyrimidine4-amino-5-hydroxymethyl-2-methylpyrimidine

Broader (1)

diazine

Papers overview

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1987
1987
Imbalance in the nucleotide pools of myeloid leukemia cells and HL-60 cells: correlation with cell-cycle phase, proliferation, differentiation, and transformation.
Myeloblasts from the blood of patients with chronic myeloid leukemia (CML) in a blastoid crisis were shown to have an imbalance… 
1984
1984
Conformational analysis of r(CGCGCG) in aqueous solution: an A-type double helical conformation studied by two-dimensional nuclear Overhauser effect spectroscopy.
The conformation of the hexanucleoside pentaphosphate r( CGCGCG ) in aqueous solution was studied by circular dichroism, 1H- and… 
Highly Cited
1983
Highly Cited
1983
Cyclobutane-type pyrimidine photodimer formation and excision in human skin fibroblasts after irradiation with 313-nm ultraviolet light.
The formation and excision of 313-nm light-induced cyclobutane-type pyrimidine photodimers were determined in confluent cultures… 
Highly Cited
1981
Highly Cited
1981
Tissue-dependent enzyme-mediated repair or removal of O-ethyl pyrimidines and ethyl purines in carcinogen-treated rats.
Treatment of perinatal rats with N-ethyl-N-nitrosourea (EtNU) leads predominantly to brain tumors. The DNA in tissues of 10-day… 
Highly Cited
1979
Highly Cited
1979
Purine and pyrimidine transport and phosphoribosylation and their interaction in overall uptake by cultured mammalian cells. A re-evaluation.
The zero-trans uptake of purines and pyrimidines was measured in suspensions of Novikoff rat hepatoma, mouse L, P388 mouse… 
Highly Cited
1966
Highly Cited
1966
Enzymatic synthesis of deoxyribonucleotides. IX. Allosteric effects in the reduction of pyrimidine ribonucleotides by the ribonucleoside diphosphate reductase system of Escherichia coli.
Abstract In Escherichia coli B the enzymatic reductions of cytidine diphosphate and uridine diphosphate require four different… 
Highly Cited
1965
Highly Cited
1965
PYRIMIDINE METABOLISM IN TISSUE CULTURE CELLS DERIVED FROM RAT HEPATOMAS. 3. RELATIONSHIP OF THYMIDINE TO THE METABOLISM OF OTHER PYRIMIDINE NUCLEOSIDES IN SUSPENSION CULTURES DERIVED FROM THE…
Summary The addition of excess thymidine (5 × 10-3m) to Novikoff tissue culture cells growing in suspension produced the… 
Highly Cited
1960
Highly Cited
1960
Studies on fluorinated pyrimidines. X. In vivo studies on tumor resistance.
Summary The biochemical mechanism of resistance has been studied at chemotherapeutic doses in mice bearing 5-fluorouracil… 
1958
1958
Pyrimidine Studies I. Effect of DON (6-Diazo-5-oxo-l-norleucine) on Incorporation of Precursors into Nucleic Acid Pyrimidines
Summary The incorporation of ureidosuccinic and orotic acid into the cytosine moiety of the nucleic acids of some mammalian… 
Highly Cited
1955
Highly Cited
1955
A Reagent for the Detection of Chloride and of Certain Purines and Pyrimidines on Paper Chromatograms
INORGANIC chloride is commonly present in mixtures of biological origin and, if not removed, may interfere with the…