Pyrimidines

Known as: PYRIMIDINE, Pyrimidines [Chemical/Ingredient] 
One of two chemical compounds that cells use to make the building blocks of DNA and RNA. Examples of pyrimidines are cytosine, thymine, and uracil… (More)
National Institutes of Health

Related topics

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50 relations

Narrower (49)

1,4-dihydropyrimidine2-methyl-5,6-cyclopentapyrimidine4-(pyridin-2-yl)pyrimidine4-amino-5-hydroxymethyl-2-methylpyrimidine
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Broader (1)

diazine

Papers overview

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Review
2017
Review
2017
Glutaminolysis: A Hallmark of Cancer Metabolism.
Glutamine is the most abundant circulating amino acid in blood and muscle and is critical for many fundamental cell functions in… (More)
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Highly Cited
2013
Highly Cited
2013
Signatures of mutational processes in human cancer
All cancers are caused by somatic mutations; however, understanding of the biological processes generating these mutations is… (More)
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Highly Cited
2013
Highly Cited
2013
Stimulation of de novo pyrimidine synthesis by growth signaling through mTOR and S6K1.
Cellular growth signals stimulate anabolic processes. The mechanistic target of rapamycin complex 1 (mTORC1) is a protein kinase… (More)
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Highly Cited
2010
Highly Cited
2010
Exome sequencing identifies the cause of a Mendelian disorder
We demonstrate the first successful application of exome sequencing to discover the gene for a rare mendelian disorder of unknown… (More)
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Highly Cited
2009
Highly Cited
2009
Synthesis of activated pyrimidine ribonucleotides in prebiotically plausible conditions
At some stage in the origin of life, an informational polymer must have arisen by purely chemical means. According to one version… (More)
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Review
2007
Review
2007
Purine and pyrimidine receptors
Adenosine 5′-triphosphate (ATP), in addition to its intracellular roles, acts as an extracellular signalling molecule via a rich… (More)
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Review
1998
Review
1998
Receptors for purines and pyrimidines.
 
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Highly Cited
1995
Highly Cited
1995
CpG motifs in bacterial DNA trigger direct B-cell activation
UNMETHYLATED CpG dinucleotides are more frequent in the gen-omes of bacteria and viruses than of vertebrates. We report here that… (More)
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Review
1994
Review
1994
Physiological concentrations of purines and pyrimidines
The concentrations of bases, nucleosides, and nucleosides mono-, di- and tri-phosphate are compared for about 600 published… (More)
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Highly Cited
1976
Highly Cited
1976
Degradation of purines and pyrimidines by microorganisms.
  • Bacteriological reviews
  • 1976
[This corrects the article on p. 403 in vol. 40.]. 
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