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Pyrimidines

Known as: PYRIMIDINE, Pyrimidines [Chemical/Ingredient] 
One of two chemical compounds that cells use to make the building blocks of DNA and RNA. Examples of pyrimidines are cytosine, thymine, and uracil… 
National Institutes of Health

Related topics

Related topics

50 relations

Narrower (49)

1,4-dihydropyrimidine2-methyl-5,6-cyclopentapyrimidine4-(pyridin-2-yl)pyrimidine4-amino-5-hydroxymethyl-2-methylpyrimidine

Broader (1)

diazine

Papers overview

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Highly Cited
2000
Highly Cited
2000
Angiogenesis, thymidine phosphorylase, and resistance of squamous cell head and neck cancer to cytotoxic and radiation therapy.
Thymidine phosphorylase (TP), an enzyme involved in the thymidine synthesis and degradation, has been shown to promote tumor… 
Highly Cited
1986
Highly Cited
1986
Hydrogen bonded and non‐hydrogen bonded van der Waals clusters: Comparison between clusters of pyrazine, pyrimidine, and benzene with various solvents
Solute–solvent clusters of pyrazine, pyrimidine, and benzene (solutes) and CnH2n+2 (n=1,2), NH3, and H2O (solvents) are studied… 
Highly Cited
1983
Highly Cited
1983
Cyclobutane-type pyrimidine photodimer formation and excision in human skin fibroblasts after irradiation with 313-nm ultraviolet light.
The formation and excision of 313-nm light-induced cyclobutane-type pyrimidine photodimers were determined in confluent cultures… 
Highly Cited
1981
Highly Cited
1981
Tissue-dependent enzyme-mediated repair or removal of O-ethyl pyrimidines and ethyl purines in carcinogen-treated rats.
Treatment of perinatal rats with N-ethyl-N-nitrosourea (EtNU) leads predominantly to brain tumors. The DNA in tissues of 10-day… 
Highly Cited
1979
Highly Cited
1979
Purine and pyrimidine transport and phosphoribosylation and their interaction in overall uptake by cultured mammalian cells. A re-evaluation.
The zero-trans uptake of purines and pyrimidines was measured in suspensions of Novikoff rat hepatoma, mouse L, P388 mouse… 
1969
1969
Cytosine arabinoside therapy for disseminated herpes zoster in a patient with IgG pyroglobulinemia.
Cytosine arabinoside is a new chemotherapeutic agent which inhibits DNA synthesis and has shown activity against experimental DNA… 
Highly Cited
1966
Highly Cited
1966
Enzymatic synthesis of deoxyribonucleotides. IX. Allosteric effects in the reduction of pyrimidine ribonucleotides by the ribonucleoside diphosphate reductase system of Escherichia coli.
Abstract In Escherichia coli B the enzymatic reductions of cytidine diphosphate and uridine diphosphate require four different… 
Highly Cited
1963
Highly Cited
1963
Polarized absorption spectra of purines and pyrimidines.
The polarized absorption spectra for single crystals of 1-methylthymine and 9-methyladenine and hydrogen-bonded complex of the… 
Highly Cited
1960
Highly Cited
1960
Studies on fluorinated pyrimidines. X. In vivo studies on tumor resistance.
Summary The biochemical mechanism of resistance has been studied at chemotherapeutic doses in mice bearing 5-fluorouracil… 
1958
1958
Pyrimidine Studies I. Effect of DON (6-Diazo-5-oxo-l-norleucine) on Incorporation of Precursors into Nucleic Acid Pyrimidines
Summary The incorporation of ureidosuccinic and orotic acid into the cytosine moiety of the nucleic acids of some mammalian…