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4-amino-5-hydroxymethyl-2-methylpyrimidine

Known as: HMP cpd 
National Institutes of Health

Related topics

Related topics

1 relation

Broader (1)

Pyrimidines

Papers overview

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Highly Cited
2017
Highly Cited
2017
The Exometabolome of Two Model Strains of the Roseobacter Group: A Marketplace of Microbial Metabolites
Recent studies applying Fourier transform ion cyclotron resonance mass spectrometry (FT-ICR-MS) showed that the exometabolome of… 
Highly Cited
2015
Highly Cited
2015
Vitamin B1 ecophysiology of marine picoeukaryotic algae: Strain‐specific differences and a new role for bacteria in vitamin cycling
We confirmed multiple picoeukaryotic algae, Ostreococcus, Micromonas, and Pelagomonas spp., as thiamine (vitamin B1) auxotrophs… 
Highly Cited
2014
Highly Cited
2014
Discovery of a SAR11 growth requirement for thiamin’s pyrimidine precursor and its distribution in the Sargasso Sea
Vitamin traffic, the production of organic growth factors by some microbial community members and their use by other taxa, is… 
2009
2009
The Vitamin B1 Metabolism of Staphylococcus aureus Is Controlled at Enzymatic and Transcriptional Levels
Vitamin B1 is in its active form thiamine pyrophosphate (TPP), an essential cofactor for several key enzymes in the carbohydrate… 
2007
2007
Molecular characterization of the thi3 gene involved in thiamine biosynthesis in Zea mays: cDNA sequence and enzymatic and structural properties of the recombinant bifunctional protein with 4-amino-5…
A thiamine biosynthesis gene, thi3, from maize Zea mays has been identified through cloning and sequencing of cDNA and… 
Highly Cited
2007
Highly Cited
2007
A new thiamin salvage pathway.
The physiological function for thiaminase II, a thiamin-degrading enzyme, has eluded investigators for more than 50 years. Here… 
2006
2006
Vitamin B1 de novo synthesis in the human malaria parasite Plasmodium falciparum depends on external provision of 4-amino-5-hydroxymethyl-2-methylpyrimidine
Abstract Vitamin B1 (thiamine) is an essential cofactor for several key enzymes of carbohydrate metabolism. Mammals have to… 
1996
1996
Amiloride toxicity in the fission yeast Schizosaccharomyces pombe is released by thiamine and mutations in the thiamine-repressible gene car1.
1994
1994
Cloning, nucleotide sequence, and regulation of Schizosaccharomyces pombe thi4, a thiamine biosynthetic gene
thi4 mutants of Schizosaccharomyces pombe exhibit defective thiamine biosynthesis, and thi4 mutations define a gene which is… 
1977
1977
Biosynthesis of thiamin in Bacillus subtilis. Isolation of mutants accumulating 4-amino-5-hydroxymethyl-2-methylpyrimidine phosphate.
Thiamin-deficient mutants of Bacillus subtilis were characterized by their growth responses to the pyrimidine and thiazole… 
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