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Phosphatidylinositol Phosphates

Known as: Phosphates, Phosphatidyl Inositol, Polyphosphoinositides, phosphatidylinositol phosphate 
Phosphatidylinositols in which one or more alcohol group of the inositol has been substituted with a phosphate group.
National Institutes of Health

Related topics

Related topics

23 relations
In BloodPhospholipase CProcess of secretionagonists
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Broader (2)

Inositol PhosphatesPhosphatidylinositols

Narrower (12)

Phosphatidylinositol 4,5-Diphosphatedimyristoylphosphatidylinositol-4-phosphatediphosphoinositidesphosphatidylinositol 3,4,5-triphosphate
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Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2014
Highly Cited
2014
MLKL compromises plasma membrane integrity by binding to phosphatidylinositol phosphates.
Although mixed lineage kinase domain-like (MLKL) protein has emerged as a specific and crucial protein for necroptosis induction… Expand
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Highly Cited
2002
Highly Cited
2002
Recruitment and regulation of phosphatidylinositol phosphate kinase type 1γ by the FERM domain of talin
Membrane phosphoinositides control a variety of cellular processes through the recruitment and/or regulation of cytosolic… Expand
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Highly Cited
2002
Highly Cited
2002
Type Iγ phosphatidylinositol phosphate kinase targets and regulates focal adhesions
The ability of cells to form cell contacts, adhere to the extracellular matrix, change morphology, and migrate is essential for… Expand
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Highly Cited
2000
Highly Cited
2000
Localized Biphasic Changes in Phosphatidylinositol-4,5-Bisphosphate at Sites of Phagocytosis
Phagocytosis requires localized and transient remodeling of actin filaments. Phosphoinositide signaling is believed to play an… Expand
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Review
2000
Review
2000
Endothelial Dysfunction, Hemodynamic Forces, and Atherogenesis a
Abstract: Phenotypic modulation of endothelium to a dysfunctional state contributes to the pathogenesis of cardiovascular… Expand
Highly Cited
1999
Highly Cited
1999
Essential Role of Phosphoinositide Metabolism in Synaptic Vesicle Recycling
Growing evidence suggests that phosphoinositides play an important role in membrane traffic. A polyphosphoinositide phosphatase… Expand
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Highly Cited
1985
Highly Cited
1985
Role of guanine nucleotide binding protein in the activation of polyphosphoinositide phosphodiesterase
Interaction of ligands with ‘Ca2+-mobilizing’ receptors is thought to result in the generation of two second messengers, inositol… Expand
Highly Cited
1983
Highly Cited
1983
Changes in the levels of inositol phosphates after agonist-dependent hydrolysis of membrane phosphoinositides.
The formation of inositol phosphates in response to agonists was studied in brain slices, parotid gland fragments and in the… Expand
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Highly Cited
1983
Highly Cited
1983
Rapid accumulation of inositol trisphosphate reveals that agonists hydrolyse polyphosphoinositides instead of phosphatidylinositol.
  • M. Berridge
  • The Biochemical journal
  • 1983
    • Corpus ID: 36936318
The agonist-dependent hydrolysis of inositol phospholipids was investigated by studying the breakdown of prelabelled lipid or by… Expand
Highly Cited
1983
Highly Cited
1983
Release of Ca2+ from a nonmitochondrial intracellular store in pancreatic acinar cells by inositol-1,4,5-trisphosphate
Activation of receptors for a wide variety of hormones and neurotransmitters leads to an increase in the intracellular level of… Expand
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